LOCUS HSU42031 2291 bp mRNA linear HUM 30-JAN-1996
DEFINITION Human 54 kDa progesterone receptor-associated immunophilin FKBP54
mRNA, partial cds.
ACCESSION U42031
VERSION U42031.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (sites)
AUTHORS Smith,D.F., Baggenstoss,B.A., Marion,T.N. and Rimerman,R.A.
TITLE Two FKBP-related proteins are associated with progesterone receptor
complexes
JOURNAL J. Biol. Chem. 268 (24), 18365-18371 (1993)
PUBMED 7688746
REFERENCE 2 (sites)
AUTHORS Smith,D.F., Albers,M.W., Schreiber,S.L., Leach,K.L. and Deibel,M.R.
Jr.
TITLE FKBP54, a novel FK506-binding protein in avian progesterone
receptor complexes and HeLa extracts
JOURNAL J. Biol. Chem. 268 (32), 24270-24273 (1993)
PUBMED 7693698
REFERENCE 3 (bases 1 to 2291)
AUTHORS Rimerman,R.A., Nair,S.C., Prapapanich,V. and Smith,D.F.
TITLE Direct Submission
JOURNAL Submitted (04-DEC-1995) Ron A. Rimerman, Pharmacology, UNMC, 600 S.
42nd St., Omaha, NE 68198, USA
FEATURES Location/Qualifiers
source 1..2291
/db_xref="H-InvDB:HIT000219800"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone_lib="HeLa S3 (semi-confluent) UniZAP XR cDNA
library (Stratagene)"
CDS <1..1351
/note="54 kDa progesterone receptor-associated
immunophilin; FK506 binding protein"
/codon_start=2
/product="FKBP54"
/protein_id="AAA86245.1"
/translation="NNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDK
VYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPE
YAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATV
EIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFG
EAGKPKFGIEPNAELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKY
MQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDK
ALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKE
HNERDRRIYANMFKKFAEQDAKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV"
BASE COUNT 751 a 452 c 565 g 523 t
ORIGIN
1 gaacaatgaa gaaagcccca cagccactgt tgctgagcag ggagaggata ttacctccaa
61 aaaagacagg ggagtattaa agattgtcaa aagagtgggg aatggtgagg aaacgccgat
121 gattggagac aaagtttatg tccattacaa aggaaaattg tcaaatggaa agaagtttga
181 ttccagtcat gatagaaatg aaccatttgt ctttagtctt ggcaaaggcc aagtcatcaa
241 ggcatgggac attggggtgg ctaccatgaa gaaaggagag atatgccatt tactgtgcaa
301 accagaatat gcatatggct cggctggcag tctccctaaa attccctcga atgcaactct
361 cttttttgag attgagctcc ttgatttcaa aggagaggat ttatttgaag atggaggcat
421 tatccggaga accaaacgga aaggagaggg atattcaaat ccaaacgaag gagcaacagt
481 agaaatccac ctggaaggcc gctgtggtgg aaggatgttt gactgcagag atgtggcatt
541 cactgtgggc gaaggagaag accacgacat tccaattgga attgacaaag ctctggagaa
601 aatgcagcgg gaagaacaat gtattttata tcttggacca agatatggtt ttggagaggc
661 agggaagcct aaatttggca ttgaacctaa tgctgagctt atatatgaag ttacacttaa
721 gagcttcgaa aaggccaaag aatcctggga gatggatacc aaagaaaaat tggagcaggc
781 tgccattgtc aaagagaagg gaaccgtata cttcaaggga ggcaaataca tgcaggcggt
841 gattcagtat gggaagatag tgtcctggtt agagatggaa tatggtttat cagaaaagga
901 atcgaaagct tctgaatcat ttctccttgc tgcctttctg aacctggcca tgtgctacct
961 gaagcttaga gaatacacca aagctgttga atgctgtgac aaggcccttg gactggacag
1021 tgccaatgag aaaggcttgt ataggagggg tgaagcccag ctgctcatga acgagtttga
1081 gtcagccaag ggtgactttg agaaagtgct ggaagtaaac ccccagaata aggctgcaag
1141 actgcagatc tccatgtgcc agaaaaaggc caaggagcac aacgagcggg accgcaggat
1201 atacgccaac atgttcaaga agtttgcaga gcaggatgcc aaggaagagg ccaataaagc
1261 aatgggcaag aagacttcag aaggggtcac taatgaaaaa ggaacagaca gtcaagcaat
1321 ggaagaagag aaacctgagg gccacgtatg acgccacgcc aaggagggaa gagtcccagt
1381 gaactcggcc cctcctcaat gggctttccc ccaactcagg acagaacagt gtttaatgta
1441 aagtttgtta tagtctatgt gattctggaa gcaaatggca aaaccagtag cttcccaaaa
1501 acagcccccc tgctgctgcc cggagggttc actgaggggt ggcacgggac cactccaggt
1561 ggaacaaaca gaaatgactg tggtgtggag ggagtgagcc agcagcttaa gtccagctca
1621 tttcagtttc tatcaacctt caagtatcca attcagggtc cctggagatc atcctaacaa
1681 tgtggggctg ttaggtttta cctttgaact ttcatagcac tgcagaaacc ttttaaaaaa
1741 aaatgcttca tgaatttctc ctttcctaca gttgggtagg gtaggggaag gaggataagc
1801 ttttgttttt taaatgactg aagtgctata aatgtagtct gttgcatttt taaccaacag
1861 aacccacagt agaggggtct catgtctccc cagttccaca gcagtgtcac agacgtgaaa
1921 gccagaacct cagaggccac ttgcttgctg acttagcctc ctcccaaagt ccccctcctc
1981 agccagcctc cttgtgagag tggctttcta ccacacacag cctgtccctg ggggagtaat
2041 tctgtcattc ctaaaacacc cttcagcaat gataatgagc agatgagagt ttctggatta
2101 gcttttccta ttttcgatga agttctgaga tactgaaatg tgaaaagagc aatcagaatt
2161 gtgctttttc tcccctcctc tattcctttt agggaataat attcaataca cagtacttcc
2221 tcccagaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2281 aaaaaaaaaa a
//