LOCUS HSU40571 2110 bp mRNA linear HUM 25-APR-1996
DEFINITION Human alpha1-syntrophin (SNT A1) mRNA, complete cds.
ACCESSION U40571
VERSION U40571.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2110)
AUTHORS Ahn,A.H., Freener,C.A., Gussoni,E., Yoshida,M., Ozawa,E. and
Kunkel,L.M.
TITLE The three human syntrophin genes are expressed in diverse tissues,
have distinct chromosomal locations, and each bind to dystrophin
and its relatives
JOURNAL J. Biol. Chem. 271 (5), 2724-2730 (1996)
PUBMED 8576247
REFERENCE 2 (bases 1 to 2110)
AUTHORS Ahn,A.H.
TITLE Direct Submission
JOURNAL Submitted (11-NOV-1995) Andrew H. Ahn, Division of Genetics, HHMI
Childrens Hosp, 300 Longwood Avenue, Boston, MA 02115, USA
FEATURES Location/Qualifiers
source 1..2110
/db_xref="H-InvDB:HIT000219726"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="20"
/map="20q11.2"
gene 1..2110
/gene="SNT A1"
CDS 38..1555
/gene="SNT A1"
/note="contains two pleckstrin homology domains and a
domain related to both the tumor discs-large protein and
the zonula occuldens protein; dystrophin-binding
intracellular membrane-associated muscle protein"
/codon_start=1
/product="alpha1-syntrophin"
/protein_id="AAC50448.1"
/translation="MASGRRAPRTGLLELRAGAGSGAGGERWQRVLLSLAEDVLTVSP
ADGDPGPEPGAPREQEPAQLNGAAEPGAGPPQLPEALLLQRRRVTVRKADAGGLGISI
KGGRENKMPILISKIFKGLAADQTEALFVGDAILSVNGEDLSSATHDEAVQVLKKTGK
EVVLEVKYMKDVSPYFKNSTGGTSVGWDSPPASPLQRQPSSPGPTPRNFSEAKHMSLK
MAYVSKRCTPNDPEPRYLEICSADGQDTLFLRAKDEASARSWATAIQAQVNTLTPRVK
DELQALLAATSTAGSQDIKQIGWLTEQLPSGGTAPTLALLTEKELLLYLSLPETREAL
SRPARTAPLIATRLVHSGPSKGSVPYDAELSFALRTGTRHGVDTHLFSVESPQELAAW
TRQLVDGCHRAAEGVQEVSTACTWNGRPCSLSVHIDKGFTLWAAEPGAARAVLLRQPF
EKLQMSSDDGASLLFLDFGGAEGEIQLDLHSCPKTIVFIIHSFLSAKVTRLGLLA"
BASE COUNT 395 a 669 c 664 g 382 t
ORIGIN
1 agggcgagcg cggcggcccg ggggctcgga ggcgaagatg gcgtccggca ggcgcgcccc
61 gcgcaccggg ctgctggagc tgcgcgccgg ggcgggctcg ggggccggcg gcgagcgatg
121 gcagcgggtg ctgctgagtc tggcggagga cgtgctgacc gtgagccccg ccgacggcga
181 ccctggtccc gagcccggcg ctccgcggga gcaggagccc gcgcagctca acggcgccgc
241 ggagccgggc gccgggcccc cgcagctgcc agaggcgcta ctgctccagc ggcgccgcgt
301 gacggtgcgc aaggccgacg ccggtgggct gggcatcagc atcaaaggcg gccgggagaa
361 caagatgcct attctcattt ccaagatctt caagggattg gcagctgacc agacagaggc
421 cctttttgtg ggggatgcca tcctgtctgt gaatggggaa gacttgtcct ctgctaccca
481 tgatgaggcg gtgcaggtcc tcaagaagac aggcaaggag gtggtgctgg aggtcaagta
541 tatgaaggac gtctcaccgt atttcaagaa ctctactggt gggacctcgg tcggctggga
601 ctcacctcct gcctcacccc ttcagcggca gccttcctcc cctggcccca caccccggaa
661 cttcagcgag gccaaacaca tgtccttgaa gatggcatat gtctcgaaga ggtgcacccc
721 caatgacccg gagcccaggt atctggagat ctgctcggca gatggtcaag acaccctctt
781 cctgagggcc aaggatgagg ctagtgcgag gtcgtgggcg actgccatcc aagcccaggt
841 caatactctg acgccgcggg tcaaggatga gctgcaggca ctgttggcag ccaccagcac
901 agctgggagc caggacatca agcagattgg ctggctaact gagcagctgc ccagtggggg
961 cacagccccc accctggccc tgctaactga aaaggaactg ctcctctact tgtctctccc
1021 cgagacccgc gaggccctga gccggccagc ccgtactgcc ccactcatcg ccaccagact
1081 ggtgcactca ggcccctcca agggctcagt gccctacgat gcagagctct cttttgccct
1141 gcgcacgggc acgcgtcacg gtgtggacac tcacctgttc agcgtggagt caccgcagga
1201 gctggctgcc tggacccgcc agcttgtgga tggctgtcac cgggccgccg agggtgtgca
1261 ggaggtgtct acagcctgca cgtggaatgg gcgtccctgc agcctgtctg tgcacatcga
1321 caagggcttc acactgtggg cggctgagcc aggtgcagcc cgagctgtgc tcctgcgaca
1381 gcccttcgag aagctgcaga tgtcttcaga tgacggtgcc agtctccttt tcctggattt
1441 tggaggtgct gaaggcgaga tccagctgga cctgcactcg tgtcccaaaa ccatagtctt
1501 catcatccac tccttcctgt cggccaaagt cacccgcctc gggctgttgg cctagaagtc
1561 gccggatgca ctagccctga agaggggtgt ccatgacatg gcctgagctg ggcctccacc
1621 gactgcctgc tcacccctgg gctgagggaa gggagaggag aggaacaagg gcctccgaaa
1681 ccccaaccct gagggagact ggattggtct tggggcccag gacccagacg caggacagag
1741 tggactctgc ctgtgatggg gtggccttcc tgctgccccc ctccaccagt gccttttgca
1801 gagagatatt ttgtgtacac agaagccatt ccgagtctgg gacctgcccc tgtgcggatc
1861 ctgaccccag ccaacagctg agctgccggg cctcctcgag gcccctaagc cacccccaga
1921 ggtcccatct gaagctggag taccctgggg tcagcagcaa gagaaagaag aggagatttt
1981 ctgtttgttt ttcccctcag ccctgccacc gtggggagtc tggtttttct cttcatcctg
2041 tctctctcct ccttactctt ggataaataa acagcctgtg agcacacagg cagcccggcc
2101 cagtaaaaaa
//