LOCUS HSPDE1C1A 2694 bp mRNA linear HUM 12-APR-1996
DEFINITION Human 3',5' cyclic nucleotide phosphodiesterase (HSPDE1C1A) mRNA,
complete cds.
ACCESSION U40371
VERSION U40371.1
KEYWORDS calmodulin-stimulated phosphodiesterase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2694)
AUTHORS Loughney,K., Martins,T.J., Harris,E.A., Sadhu,K., Hicks,J.B.,
Sonnenburg,W.K., Beavo,J.A. and Ferguson,K.
TITLE Isolation and characterization of cDNAs corresponding to two human
calcium, calmodulin-regulated, 3',5'-cyclic nucleotide
phosphodiesterases
JOURNAL J. Biol. Chem. 271 (2), 796-806 (1996)
PUBMED 8557689
REFERENCE 2 (bases 1 to 2694)
AUTHORS Loughney,K., Martins,T.J., Harris,E.A.S., Sadhu,K., Hicks,J.B.,
Sonnenburg,W.K., Beavo,J.A. and Ferguson,K.
TITLE Direct Submission
JOURNAL Submitted (07-NOV-1995) Kate Loughney, ICOS, 22021 20th Ave. S.E.,
Bothell, WA 98021, USA
FEATURES Location/Qualifiers
source 1..2694
/db_xref="H-InvDB:HIT000219714"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..2694
/gene="PDE1C"
CDS 177..2081
/gene="PDE1C"
/note="PDE1C1; splice variant"
/codon_start=1
/product="3',5' cyclic nucleotide phosphodiesterase"
/protein_id="AAC50437.1"
/translation="MESPTKEIEEFESNSLKYLQPEQIEKIWLRLRGLRKYKKTSQRL
RSLVKQLERGEASVVDLKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAVPSEV
RDWLASTFTRQMGMMLRRSDEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVI
EALKDVDKWSFDVFSLNEASGDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEV
GYSKHKNPYHNLMHAADVTQTVHYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTT
NNFHIQTRSDPAILYNDRSVLENHHLSAAYRLLQDDEEMNILINLSKDDWREFRTLVI
EMVMATDMSCHFQQIKAMKTALQQPEAIEKPKALSLMLHTADISHPAKAWDLHHRWTM
SLLEEFFRQGDREAELGLPFSPLCDRKSTMVAQSQVGFIDFIVEPTFTVLTDMTEKIV
SPLIDETSQTGGTGQRRSSLNSISSSDAKRSGVKTSGSEGSAPINNSVISVDYKSFKA
TWTEVVHINRERWRAKVPKEEKAKKEAEEKARLAAEEQQKEMEAKSQAEEGASGKAEK
KTSGETKNQVNGTRANKSDNPRGKNSKAEKSSGEQQQNGDFKDGKNKTDKKDHSNIGN
DSKKTDDSQE"
BASE COUNT 777 a 618 c 652 g 647 t
ORIGIN
1 gtcgcttcaa tatttcaaaa tggatccggt tctgtggcgg gtgcgagagt gaggctgtgg
61 gggacctcca ggccgaacct ccgcgaagcc tcgcggcttc tgcgtgccct ggccccggga
121 ggataaggat ttcccttccc tcctacttgc gcgcggagcc gagctcttgt tgagctatgg
181 agtcgccaac caaggagatt gaagaatttg agagcaactc tctgaaatac ctgcaaccgg
241 aacagatcga gaaaatctgg cttcggctcc gcgggctgag gaaatataag aaaacgtccc
301 agagattacg gtctttggtc aaacaattag agagagggga agcttcagtg gtagatctta
361 agaagaattt ggaatatgca gccacagtgc ttgaatctgt gtatattgat gaaacaagga
421 gactcctgga tacagaggat gagctcagtg acattcagtc agatgctgtg ccttctgagg
481 tccgagactg gctggcctcc accttcacgc ggcagatggg gatgatgctc aggaggagcg
541 acgagaagcc ccggttcaag agcatcgttc acgcagtgca ggctgggata tttgtggaga
601 gaatgtatag acggacatca aacatggttg gactgagcta tccaccagct gttattgagg
661 cattaaagga tgtggacaag tggtcctttg acgtcttttc cctcaatgag gccagtgggg
721 atcatgcact gaaatttatt ttctatgaac tactcacacg ttatgatctg atcagccgtt
781 tcaagatccc catttctgca cttgtctcat ttgtggaggc cctggaagtg ggatacagca
841 agcacaaaaa tccttaccat aacttaatgc acgctgccga tgttacacag acagtgcatt
901 acctcctcta taagacagga gtggcgaact ggctgacgga gctggagatc tttgctataa
961 tcttctcagc tgccatccat gactacgagc ataccggaac caccaacaat ttccacattc
1021 agactcggtc tgatccagct attctgtata atgacagatc tgtactggag aatcaccatt
1081 taagtgcagc ttatcgcctt ctgcaagatg acgaggaaat gaatattttg attaacctct
1141 caaaggatga ctggagggag tttcgaacct tggtaattga aatggtgatg gccacagata
1201 tgtcttgtca cttccaacaa atcaaagcaa tgaagactgc tctgcagcag ccagaagcca
1261 ttgaaaagcc aaaagcctta tcccttatgc tgcatacagc agatattagc catccagcaa
1321 aagcatggga cctccatcat cgctggacaa tgtcactcct ggaggagttc ttcagacagg
1381 gtgacagaga agcagagctg gggctgcctt tttctcctct gtgtgaccga aagtccacta
1441 tggttgctca gtcacaagta ggtttcattg atttcatcgt ggaacccacc ttcactgtgc
1501 ttacggacat gaccgagaag attgtgagtc cattaatcga tgaaacctct caaactggtg
1561 ggacaggaca gaggcgttcg agtttgaata gcatcagctc gtcagatgcc aagcgatcag
1621 gtgtcaagac ctctggttca gagggaagtg ccccgatcaa caattctgtc atctccgttg
1681 actataagag ctttaaagct acttggacgg aagtggtgca catcaatcgg gagagatgga
1741 gggccaaggt acccaaagag gagaaggcca agaaggaagc agaggaaaag gctcgcctgg
1801 ccgcagagga gcagcaaaag gaaatggaag ccaaaagcca ggctgaagaa ggcgcatctg
1861 gcaaagctga gaaaaagacg tctggagaaa ctaagaatca agtcaatgga acacgggcaa
1921 acaaaagtga caaccctcgt gggaaaaatt ccaaagccga gaagtcatca ggagaacagc
1981 aacagaatgg tgacttcaaa gatggtaaaa ataagacaga caagaaggat cactctaaca
2041 tcggaaatga ttcaaagaaa acagatgatt cacaagagta aaaaagacct catagacaat
2101 aaaagaggct gccagtgtct tgcatcattc tagctgagct tcttcattct ccttcttctc
2161 cttcttccac aaagacccat atctggagaa ggtgtacaac tttcaaacac aagcccccca
2221 ccccctgacc cttggccttc cctcacacca tctccttcca ggggatgaat ctttgggggt
2281 tggtttgagg tcttagaact ctgggggata ttcccctgag caaaacaaac aacgtgagat
2341 ttttactcaa acagaaacaa aacatgaagg ggcatcctca aaatcctttg ctaatgacct
2401 ggctttcaag gcatctgtct ggcctgatga gaatggacat cctggatatg ctgggagagg
2461 cctgaaaaaa gccacacaca cagtaattgc cattttatga ctgtcaatgc cgttacttta
2521 aatgttgtca tttttgcact ggctactgat gatacagcca tgctgacatt catcaccgca
2581 aagatgatga ttccagtctc tggttccttt cctgagtcag gaacatttgt tttctccaat
2641 ttcctttcag acttaaaatt gttcttatgc tttttttccc acttctgtaa taca
//