LOCUS HSU40282 1789 bp mRNA linear HUM 21-MAY-1998
DEFINITION Homo sapiens integrin-linked kinase (ILK) mRNA, complete cds.
ACCESSION U40282
VERSION U40282.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1789)
AUTHORS Hannigan,G.E., Leung-Hagesteijn,C., Fitz-Gibbon,L., Coppolino,M.G.,
Radeva,G., Filmus,J., Bell,J.C. and Dedhar,S.
TITLE Regulation of cell adhesion and anchorage-dependent growth by a new
beta 1-integrin-linked protein kinase
JOURNAL Nature 379 (6560), 91-96 (1996)
PUBMED 8538749
REFERENCE 2 (bases 1 to 1789)
AUTHORS Dedhar,S. and Hannigan,G.E.
TITLE Direct Submission
JOURNAL Submitted (07-NOV-1995) Shoukat Dedhar, Cancer Biology Research,
Sunnybrook Health Science Centre and University of Toronto, 2075
Bayview Avenue, North York, Ont. M4N 3M5, Canada
REFERENCE 3 (bases 1 to 1789)
AUTHORS Dedhar,S. and Hannigan,G.E.
TITLE Direct Submission
JOURNAL Submitted (21-MAY-1998) Shoukat Dedhar, Cancer Biology Research,
Sunnybrook Health Science Centre and University of Toronto, 2075
Bayview Avenue, North York, Ont. M4N 3M5, Canada
REMARK Sequence update by submitter
COMMENT On May 21, 1998 this sequence version replaced gi:2648173.
FEATURES Location/Qualifiers
source 1..1789
/db_xref="H-InvDB:HIT000219709"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="11"
/map="11p15"
/cell_line="HeLa"
gene 1..1789
/gene="ILK"
CDS 157..1515
/gene="ILK"
/note="protein serine/threonine kinase"
/codon_start=1
/product="integrin-linked kinase"
/protein_id="AAC16892.1"
/translation="MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACRE
GRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNV
PLHYACFWGQDQVAEDLVANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLN
RIPYKDTFWKGTTRTRPRNGTLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIV
VKVLKVRDWSTRKSRDFNEECPRLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGS
LYNVLHEGTNFVVDQSQAVKFALDMARGMAFLHTLEPLIPRHALNSRSVMIDEDMTAR
ISMADVKFSFQCPGRMYAPAWVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPF
ADLSNMEIGMKVALEGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFDMIVPILEKMQ
DK"
BASE COUNT 443 a 488 c 480 g 378 t
ORIGIN
1 gaattcatct gtcgactgct accacgggag ttccccggag aaggatcctg cagcccgagt
61 cccgaggata aagcttgggg ttcatcctcc ttccctggat cactccacag tcctcaggct
121 tccccaatcc aggggactcg gcgccgggac gctgctatgg acgacatttt cactcagtgc
181 cgggagggca acgcagtcgc cgttcgcctg tggctggaca acacggagaa cgacctcaac
241 cagggggacg atcatggctt ctcccccttg cactgggcct gccgagaggg ccgctctgct
301 gtggttgaga tgttgatcat gcggggggca cggatcaatg taatgaaccg tggggatgac
361 acccccctgc atctggcagc cagtcatgga caccgtgata ttgtacagaa gctattgcag
421 tacaaggcag acatcaatgc agtgaatgaa cacgggaatg tgcccctgca ctatgcctgt
481 ttttggggcc aagatcaagt ggcagaggac ctggtggcaa atggggccct tgtcagcatc
541 tgtaacaagt atggagagat gcctgtggac aaagccaagg cacccctgag agagcttctc
601 cgagagcggg cagagaagat gggccagaat ctcaaccgta ttccatacaa ggacacattc
661 tggaagggga ccacccgcac tcggccccga aatggaaccc tgaacaaaca ctctggcatt
721 gacttcaaac agcttaactt cctgacgaag ctcaacgaga atcactctgg agagctatgg
781 aagggccgct ggcagggcaa tgacattgtc gtgaaggtgc tgaaggttcg agactggagt
841 acaaggaaga gcagggactt caatgaagag tgtccccggc tcaggatttt ctcgcatcca
901 aatgtgctcc cagtgctagg tgcctgccag tctccacctg ctcctcatcc tactctcatc
961 acacactgga tgccgtatgg atccctctac aatgtactac atgaaggcac caatttcgtc
1021 gtggaccaga gccaggctgt gaagtttgct ttggacatgg caaggggcat ggccttccta
1081 cacacactag agcccctcat cccacgacat gcactcaata gccgtagtgt aatgattgat
1141 gaggacatga ctgcccgaat tagcatggct gatgtcaagt tctctttcca atgtcctggt
1201 cgcatgtatg cacctgcctg ggtagccccc gaagctctgc agaagaagcc tgaagacaca
1261 aacagacgct cagcagacat gtggagtttt gcagtgcttc tgtgggaact ggtgacacgg
1321 gaggtaccct ttgctgacct ctccaatatg gagattggaa tgaaggtggc attggaaggc
1381 cttcggccta ccatcccacc aggtatttcc cctcatgtgt gtaagctcat gaagatctgc
1441 atgaatgaag accctgcaaa gcgacccaaa tttgacatga ttgtgcctat ccttgagaag
1501 atgcaggaca agtaggactg gaaggtcctt gcctgaactc cagaggtgtc gggacatggt
1561 tgggggaatg cacctcccca aagcagcagg cctctggttg cctcccccgc ctccagtcat
1621 ggtactaccc cagcctgggg tccatcccct tcccccatcc ctaccactgt gcgcaagagg
1681 ggcgggctca gagctttgtc acttgccaca tggtgtcttc caacatggga gggatcagcc
1741 ccgcctgtca caataaagtt tattatgaaa aaaaaaaaaa aaaaaaaaa
//