LOCUS AH005363 5624 bp DNA linear HUM 28-JUL-2016
DEFINITION Homo sapiens clone alpha W.1 beta-2 integrin alphaD subunit (ITGAD)
gene, partial cds.
ACCESSION AH005363 U40274 U40275 U40276 U40277 U40278 U40279
VERSION AH005363.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5624)
AUTHORS Wong,D.A., Davis,E.M., LeBeau,M. and Springer,T.A.
TITLE Cloning and chromosomal localization of a novel gene-encoding a
human beta 2-integrin alpha subunit
JOURNAL Gene 171 (2), 291-294 (1996)
PUBMED 8666289
REFERENCE 2 (bases 1 to 5624)
AUTHORS Wong,D.A.
TITLE Direct Submission
JOURNAL Submitted (07-NOV-1995) Dennis A. Wong, McMaster University,
Medicine, 1200 Main St. West, Hamilton, On L8N 3Z5, Canada
COMMENT On or before Apr 6, 2016 this sequence version replaced U40274.1,
U40275.1, U40276.1, U40277.1, U40278.1, U40279.1, AH005363.1.
FEATURES Location/Qualifiers
source 1..5624
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/clone="alpha W.1"
/clone_lib="pWE15 Genomic"
gene 1..4752
/gene="ITGAD"
CDS join(<1..99,190..>297)
/gene="ITGAD"
/codon_start=1
/product="beta-2 integrin alphaD subunit"
/protein_id="AAB60634.1"
/translation="DSDGSTDLILIGAPHYYEQTRGGQVSVCPLPRGRVQWQCDAVLR
GEQATPGRFGAALTVLGDVNEDKLI"
exon <1..99
/gene="ITGAD"
/note="encodes metal-binding domain"
/number=14
intron 100..189
/gene="ITGAD"
/experiment="experimental evidence, no additional details
recorded"
exon 190..>297
/gene="ITGAD"
/note="encodes metal-binding domain"
/number=15
gap 298..397
/estimated_length=unknown
intron <398..401
/gene="ITGAD"
CDS <402..>498
/gene="ITGAD"
/codon_start=1
/product="beta-2 integrin alphaD subunit"
/protein_id="AAB60635.1"
/translation="RIASSQLSPRLQYFGQALSGGQDLTQDGLMDL"
exon 402..>498
/gene="ITGAD"
/number=16
gap 499..598
/estimated_length=unknown
CDS <599..>702
/gene="ITGAD"
/codon_start=2
/product="beta-2 integrin alphaD subunit"
/protein_id="AAB60636.1"
/translation="AKAVYRCWEEKPSALEAGDATVCLTIQKSSLDQL"
exon <599..702
/gene="ITGAD"
/number=17
intron 703..>727
/gene="ITGAD"
gap 728..827
/estimated_length=unknown
intron <828..924
/gene="ITGAD"
CDS <925..>1066
/gene="ITGAD"
/codon_start=2
/product="beta-2 integrin alphaD subunit"
/protein_id="AAB60637.1"
/translation="LQTLTVGSSLELNVIVTVWNAGEDSYGTVVSLYYPAGVSHRRVS
GAQ"
exon 925..1066
/gene="ITGAD"
/number=21
intron 1067..>1182
/gene="ITGAD"
gap 1183..1282
/estimated_length=unknown
CDS join(<1283..1339,3289..3367,3528..3635,3747..3824,
4020..4133,4277..4378,4642..>4752)
/gene="ITGAD"
/codon_start=2
/product="beta-2 integrin alphaD subunit"
/protein_id="AAB60638.1"
/translation="ATFQLELPVKYAVYTMISRQEESTKYFNFATSDEKKMKEAEHRY
RVNNLSQRDLAISINFWVPVLLNGVAVWDVAMEAPSQSLPCVSERKPPQHSDFLTQIS
RSPMLDCSIADCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQKKVLVVSVAEIT
FDTSVYSQLPGQEAFMRAQMEMVLEEDEVYNAIPIIMGSSVGALLLLALITATLYK"
exon <1283..1339
/gene="ITGAD"
/number=24
intron 1340..>1381
/gene="ITGAD"
gap 1382..1481
/estimated_length=unknown
intron <1482..3288
/gene="ITGAD"
exon 3289..3367
/gene="ITGAD"
/number=25
intron 3368..3527
/gene="ITGAD"
exon 3528..3635
/gene="ITGAD"
/number=26
intron 3636..3746
/gene="ITGAD"
exon 3747..3824
/gene="ITGAD"
/number=27
intron 3825..4019
/gene="ITGAD"
exon 4020..4133
/gene="ITGAD"
/number=28
intron 4134..4276
/gene="ITGAD"
exon 4277..4378
/gene="ITGAD"
/number=29
intron 4379..4641
/gene="ITGAD"
exon 4642..4752
/gene="ITGAD"
/number=30
misc_feature 4678..4752
/gene="ITGAD"
/note="encodes likely transmembrane region"
intron 4753..>5624
/note="GC at 5' of this intron"
BASE COUNT 1122 a 1345 c 1398 g 1230 t
ORIGIN
1 gacagcgatg gcagcaccga cctgatcctc attggggccc ctcattacta tgagcagacc
61 cgagggggcc aggtgtccgt gtgtcccttg cctagggggg tgagtggctg atggacctag
121 gctgggtggg gtccggtgtg agtggaggcg tcacctggat tggggtctga cactgcttgt
181 gttcagcaga gggtgcagtg gcagtgtgac gctgttctcc gtggtgagca ggccacccct
241 ggccgctttg gggcagccct gacagtgttg ggggatgtga atgaggacaa gctgatannn
301 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
361 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnncca gcggattgcc agctcccagc
421 tctcccccag gctgcagtat tttggacagg cgctgagtgg gggtcaggac ctcacccagg
481 atggactgat ggacctggnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
541 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnngg
601 ccaaggctgt gtaccggtgc tgggaagaga agcccagtgc cctggaagct ggggacgcca
661 ccgtctgtct caccatccag aaaagctcac tggaccagct aggtgtgttt cccccataaa
721 gggggccnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnccc agagctccag
841 agttcctggg attctgccct gcccttccca gttcccacct atttccagtg gagcgccact
901 cccagcctcg tccttcccct tcagcctgca gaccctgacc gtggggagct ccctggagct
961 caacgtgatt gtgactgtgt ggaacgcagg tgaggattcc tacggaaccg tggtcagcct
1021 ctactatcca gcaggggtgt cgcaccgacg ggtgtcagga gcccaggtaa caactgctgt
1081 aggctctagt gggagggggc ctaaggagtt ggttttatca tttctgcgtt ttatagaaag
1141 aaactaaggc tgaccaaggc tgtcagtcac ctgcctaagg ccnnnnnnnn nnnnnnnnnn
1201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
1261 nnnnnnnnnn nnnnnnnnnn nnggccacct tccagctgga gctcccggtg aagtatgcag
1321 tctacaccat gatcagcagg tgcccagtcc ctggccatga gattcagccc tgtggaggtg
1381 gnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
1441 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ntgaaaacag gcttaggctg
1501 cgcacggtgg ctcgtgcctg taatcccagc actttgggag gccaagtgct gggattacag
1561 gcatgagtgg gaggatggct tgaccccagg agtttacgac cccccggggc aacatagtga
1621 gaacccatct ctaccaaaaa aaaaaaatta aaaatgaaaa taaaataaaa ctttaaaaat
1681 gaaaagaggt ttagaactag attttaagat gagaaaacag aagcatagag agaagggttt
1741 ggggtggggg gcacagagga aaacccgcat acttagggaa aaataaacct taagatttat
1801 ggaggagtcc ctgtgtgctg ggcactacca agccctggtc acaactctac tacagggagg
1861 ttgctacggt ttgcatcccc antttaaaga gtgaaaagct acagtttcca gagacgtgaa
1921 gtggcttgcc tcagtgactc aggtaggaag tggtcgacct gagatgtgaa cctaggcggt
1981 ttgacactgg agcccatgtt tttagtcatc aggctgatgg ggggtggact gctggggctg
2041 tttctgnntg gctggtctgg ctgctgcatg cgaggtgcag gcccctctgc tggtctgctt
2101 actttngctt ttngtttgtt tngagacagg gtctcactct gtcacccagg ctggagggga
2161 gtgggtgtna acatagctta ctgcagcctc gacctcccag gntcaagcaa tcctcctgcc
2221 tcagcctcct gagtagctgg gaccacaggc gtntnccacc acttgcagct aatgtttgta
2281 tttttttttt tttnggnaga gacgaggtct ctctgtgttg cccaggccag tcttgaactc
2341 ctgggctcaa gcgattcttc tgccttagtc tctctaagtg ttgggattac aggcgtgagc
2401 cacctcgcct ggccagcttg ctcattttta ctaaaacttt agatgttaag tggtgagagg
2461 gcagggagtt atggcttaac ttgaatcccc agtgccaacc acacagcctg tgtttcctga
2521 aggaagtttg ggtggaaaga ccccacctgc tgcctggaac actgatgtcc cttccacagg
2581 cttgtgcaca ggcactatct tccttcacat ttactcacct gccccaggac agccgaatct
2641 attttcttca ttcccaccat gaaggggccc tcactccatg tcttcctgag tgatccagct
2701 ctcattccta gagtcccctt aggctaactt gttctgctac aatctctgta agcattacca
2761 gaggccaaac actacctatt agagaaagca atgcaaacgc ctttgcccca tgtaggngac
2821 atgaggttta agttgggtct ttaagtgtaa atttccaaaa ctggagacag taagaacgtt
2881 ccaaggagaa gagcttgagc aaagtcatga ggctatgaaa gagccagcgg tgtgcatggc
2941 agagctagtg gatctgggtg atgggggcaa gggacatcgg agggagggga gctgaagccg
3001 aggcagcaaa ggttatgtgg gaccatcttt tacttattta ctttggatag ggacagggtc
3061 tcacgatgtt gccccagctg gtctggaact cctgggttca agaaaccctc ctgccccagc
3121 ctcccaagtt ctgggattac aggcatgagc ccactgtgcc cggccaaata atgtccatcg
3181 ttatttccct gagacatctg cccagcccaa cagagctctc tgcagtagga cccggcacaa
3241 ctggggacag tttcagggct gtttttcacc cacaggctct ctctccaggc aggaagaatc
3301 caccaagtac ttcaactttg caacctccga tgagaagaaa atgaaagagg ctgagcatcg
3361 ataccgtgtg agagtctagg gagtatccat gtctcccttc cccgttgtgg ataaaggtgg
3421 aagttggtgg agaagatgga gaggagcctt ggggtagggc cagggggggg ggtaggattt
3481 ggaaggctcc agagaccaca ataacactct gccttgattt cctgcaggtg aataacctca
3541 gccagcgaga tctggccatc agcattaact tctgggttcc tgtcctgctg aacggggtgg
3601 ctgtgtggga tgtggccatg gaggccccat ctcaggtagc cgcctatctc tcctctttct
3661 tcagactgac atcccacagc acagcactcc ctcttaccag ggagatgttg ctcattctgt
3721 ggctaagtgc ttctttctct tcccagagtc tcccctgtgt ttcagagaga aaacctcccc
3781 agcattctga cttcctgacc cagatttcaa gaagtcccat gctggtgaga aagtccctga
3841 accccccccg ccaagannag cccccnccgg gganactggg agatgtnctg ctaggccaca
3901 gagttccgtg catgtcctgt aactgctcat ctgttcccca ccccaaacct gacaaatttt
3961 tccctatggc tcccctcctc agggaagaac cctcagtttc acccctcttc tgcccccagg
4021 actgctccat tgctgactgc ctgcagttcc gctgtgacgt cccctccttc agcgtccagg
4081 aggagctgga tttcaccctg aagggcaatc tcagtttcgg ctgggtccgc gaggtgtgtg
4141 ggggcagcgg cagagcccct gccccagact caggcaggac ctggcatgtc tgtgcccatc
4201 tgcaagccag ggcaccccca gagctctgag cctcccccag agccagttcc acaggtnncc
4261 cccaacccct ttgcagacat tgcagaagaa ggtgttggtc gtgagtgtgg ctgaaattac
4321 gttcgacaca tccgtgtact cccagcttcc aggacaggag gcatttatga gagctcaggt
4381 agagaccatg tggagggcag cnaccagctg gaaagaggac ccctagggnt acatctgtgg
4441 tgctgggtgg ggggtttgca agccttgcgg gaggagggtg annntctctg ggcagnacag
4501 ctctccctaa gggcacgggt gctactgtnt ctcactcctg ggagcaganc ctcagaaagg
4561 aggggagaga gttaaaggtt gcggaacctg ggaggcatct gggatggcat gaggccggat
4621 gctctctgat ctctaaatca gatggagatg gtgctagaag aagacgaggt ctacaatgcc
4681 attcccatca tcatgggcag ctctgtgggg gctctgctac tgctggcgct catcacagcc
4741 acactgtaca aggcaagtgt tttatccaac tctttttttt ttttttttga gatggagttt
4801 ccactcttac tgcccaggct ggagtgcaat ggcatgatct tggctcactg caacctccac
4861 ctcccgggta caagtgattc tcctgtctca gcctcccgag tagctgggat tacaggtgga
4921 ctgcaccatg cccggctagt tttttgtatt tttagtagag atggagtttc atcatgttgg
4981 ccaggctggt ctcgaactcc tgacttcagg tgatccgccc accttggcct cccaaagttc
5041 tgggattaca ggtgtgagcc acctcatccg gccttatccc attcttgaca ccaccagcat
5101 ccaacccaag ccctcctaca gactggctga tatagtgaga actcagactg tggaggcaga
5161 caggcctgga cacacaattt ggctctatca tgtactcact gtttaatgtt aggcaagttg
5221 ctccacctct ctaagcctgt ttctctcttt cttttttttc ttttgagatg gagtctcact
5281 cagttgccta ggctggggtg cagtggcaca atctcagctc actgcaacct ccacctccta
5341 gggtcaaaag attctcatgc ctcagcttcc caagtagcta ggactacagg cacacaccac
5401 cacacctggc tattttttgt atttttagta gagagaggtt tcaccatgtt ggtcagattg
5461 gtctcaaact cctgacctca tgtgatccgc ccacctcggc ctcccaaact gctgggntta
5521 caggcatgag ccactgtgcc cggccgtttc tcatttttga aatgataata atgcttatat
5581 cacagagtgg ctgaagtgag agagaaatga ggccagggca tgtg
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