LOCUS HSU39657 2871 bp mRNA linear HUM 14-NOV-2016
DEFINITION Homo sapiens MAP kinase kinase 6 (MKK6) mRNA, complete cds.
ACCESSION U39657
VERSION U39657.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2871)
AUTHORS Raingeaud,J., Whitmarsh,A.J., Barrett,T., Derijard,B. and
Davis,R.J.
TITLE MKK3- and MKK6-regulated gene expression is mediated by the p38
mitogen-activated protein kinase signal transduction pathway
JOURNAL Mol. Cell. Biol. 16 (3), 1247-1255 (1996)
PUBMED 8622669
REFERENCE 2 (bases 1 to 2871)
AUTHORS Raingeaud,J., Barrett,T. and Davis,R.J.
TITLE Direct Submission
JOURNAL Submitted (27-OCT-1995) Roger J. Davis, Molecular Medicine, HHMI
and UMASS Medical School, 373 Plantation Street, Worcester, MA
01605, USA
COMMENT On Nov 14, 2016 this sequence version replaced U39657.1.
FEATURES Location/Qualifiers
source 1..2871
/db_xref="H-InvDB:HIT000219695"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="skeletal muscle"
gene 1..2871
/gene="MKK6"
CDS 288..1292
/gene="MKK6"
/function="MAP kinase kinase 6 phosphorylates and
activates p38 MAP kinase"
/note="protein kinase"
/codon_start=1
/product="MAP kinase kinase 6"
/protein_id="AAC50389.1"
/translation="MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQ
NFEVKADDLEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDI
SMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAV
SIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKP
YMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSP
QLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKGTDVASFVKLILGD
"
BASE COUNT 831 a 545 c 641 g 854 t
ORIGIN
1 gttccaagtt tggagctttt agctgccagc cctggcccat catgtagctg cagcacagcc
61 ttccctaacg ttgcaactgg gggaaaaatc actttccagt ctgttttgca aggtgtgcat
121 ttccatcttg attccctgaa agtccatctg ctgcatcggt caagagaaac tccacttgca
181 tgaagattgc acgcctgcag cttgcatctt tgttgcaaaa ctagctacag aagagaagca
241 aggcaaagtc ttttgtgctc ccctccccca tcaaaggaaa ggggaaaatg tctcagtcga
301 aaggcaagaa gcgaaaccct ggccttaaaa ttccaaaaga agcatttgaa caacctcaga
361 ccagttccac accacctaga gatttagact ccaaggcttg catttctatt ggaaatcaga
421 actttgaggt gaaggcagat gacctggagc ctataatgga actgggacga ggtgcgtacg
481 gggtggtgga gaagatgcgg cacgtgccca gcgggcagat catggcagtg aagcggatcc
541 gagccacagt aaatagccag gaacagaaac ggctactgat ggatttggat atttccatga
601 ggacggtgga ctgtccattc actgtcacct tttatggcgc actgtttcgg gagggtgatg
661 tgtggatctg catggagctc atggatacat cactagataa attctacaaa caagttattg
721 ataaaggcca gacaattcca gaggacatct tagggaaaat agcagtttct attgtaaaag
781 cattagaaca tttacatagt aagctgtctg tcattcacag agacgtcaag ccttctaatg
841 tactcatcaa tgctctcggt caagtgaaga tgtgcgattt tggaatcagt ggctacttgg
901 tggactctgt tgctaaaaca attgatgcag gttgcaaacc atacatggcc cctgaaagaa
961 taaacccaga gctcaaccag aagggataca gtgtgaagtc tgacatttgg agtctgggca
1021 tcacgatgat tgagttggcc atccttcgat ttccctatga ttcatgggga actccatttc
1081 agcagctcaa acaggtggta gaggagccat cgccacaact cccagcagac aagttctctg
1141 cagagtttgt tgactttacc tcacagtgct taaagaagaa ttccaaagaa cggcctacat
1201 acccagagct aatgcaacat ccatttttca ccctacatga atccaaagga acagatgtgg
1261 catcttttgt aaaactgatt cttggagact aaaaagcagt ggacttaatc ggttgaccct
1321 actgtggatt ggtgggtttc ggggtgaagc aagttcacta cagcatcaat agaaagtcat
1381 ctttgagata atttaaccct gcctctcaga gggttttctc tcccaatttt ctttttactc
1441 cccctcttaa gggggccttg gaatctatag tatagaatga actgtctaga tggatgaatt
1501 atgataaagg cttaggactt caaaaggtga ttaaatattt aatgatgtgt catatgagtc
1561 ctcaagcttc tcagacttct cttattcttt acaaaatgaa tgcattggcc ctgacaaaaa
1621 ggtgctacgg tagtgatgaa attataagta gatttgtagt ttgtcccatt tattatttta
1681 atatttatgt ttaagtgctt ggttgaaaag attccatttt atacaagaag ggagattcaa
1741 aaaaaaaata taaggttggg ttagcaatat ttatagggct tttatttttt aagttcaatt
1801 gtgtctgtgg tccagaagaa attatttaat atgcatcttt gagaatatta taaaaatatc
1861 aaaaaggagc tcttcttgtg aaatgtctgt tccagctgtt gtgactgctg ccatttttgg
1921 aaacatctgc ccaatcctgg gtgatcacca catcttttag gggaagtgac aagatgctct
1981 ggtcatactc tttttcccaa ctttggaaaa cataaaaatc actcatataa cagctcaaag
2041 agtaaaacat ttggttcttc tgacacttgt ggtatagtat tagtggaaag tgatttgtaa
2101 tatgatttta tatccaccta cctattcatc tacctgtgtg tatgtgtgtg tttgtgtgtc
2161 tatttggcaa ttcacaagtc ctgccaagtg gtttctatga gcatctctgt ttggtaagga
2221 ggacaattgt cagttttgag ggggacatgt gttaaatcac agaaaaaaat ggtgccttct
2281 tctgcgtttg tccctcctgc catgtgtaag ttgtaaggat tgcctttgta gttaatgtac
2341 tctttggctt tgtttgtttg ttttcttctt cagtgaagca gccttactat tcatagaagg
2401 gctagaatag gagaaaatga aaggtagtga gtaattcttt gataagatga ggaaataatg
2461 ggaaaggttg aattaattcc tgggcatgga ctaccagatg accacaagtt gcgttgaggc
2521 cgcatctttc ttcagcagcg tgcaatagct ggctcctcta taggagatga gcttcattgg
2581 gagttcctag caagttgact aaacagcaaa agttctttct cgtgggtaaa tatacccaca
2641 ggttctatga tttgtagctc taggtttctt gatgatcaag gagtgaagta attgacaggg
2701 aaaatataga cctatgataa ataaccagga agcattgctt ttggacaagg aagaacagag
2761 ggttttgatt ttaaaaagaa gaaaaaaaaa ccttattttt tctttcttgg cctcaagttc
2821 aatatggaga ggattgcttc cctgaatcct ctcttccttc cccttttaga g
//