LOCUS HSU38480 1594 bp mRNA linear HUM 08-NOV-1995
DEFINITION Human retinoid X receptor-gamma mRNA, complete cds.
ACCESSION U38480
VERSION U38480.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1594)
AUTHORS Cooke,T.A., Allegretto,E.A., Heyman,R.A. and Lamph,W.W.
TITLE Cloning and characterization of the human retinoid X receptor
(RXR)-gamma isoform of retinoid receptors
JOURNAL Unpublished
REFERENCE 2 (sites)
AUTHORS Mangelsdorf,D.J., Borgmeyer,U., Heyman,R.A., Zhou,J.Y., Ong,E.S.,
Oro,A.E., Kakizuka,A. and Evans,R.M.
TITLE Characterization of three RXR genes that mediate the action of
9-cis retinoic acid
JOURNAL Genes Dev. 6 (3), 329-344 (1992)
PUBMED 1312497
REFERENCE 3 (bases 1 to 1594)
AUTHORS Lamph,W.W.
TITLE Direct Submission
JOURNAL Submitted (12-OCT-1995) William W. Lamph, Ligand Pharmaceuticals
Inc., Retinoid Research, 9393 Towne Centre Dr., San Diego, CA
92121, USA
FEATURES Location/Qualifiers
source 1..1594
/db_xref="H-InvDB:HIT000219592"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="p27103"
/sex="male"
/tissue_type="heart"
CDS 28..1419
/function="ligand dependent transcription factor"
/note="RXR-gamma; hRXR-g"
/citation=[1]
/codon_start=1
/product="retinoid X receptor-gamma"
/protein_id="AAA80681.1"
/translation="MYGNYSHFMKFPAGYGGSPGHTGSTSMSPSAALSTGKPMDSHPS
YTDTPVSAPRTLSAVGTPLNALGSPYRVITSAMGPPSGALAAPPGINLVAPPSSQLNV
VNSVSSSEDIKPLPGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCK
GFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRE
RAESEAECATSGHEDMPVERILEAELAVEPKTESYGDMNMENSTNDPVTNICHAADKQ
LFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVH
RSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVET
LREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDT
FLMEMLETPLQIT"
regulatory 1544..1549
/regulatory_class="polyA_signal_sequence"
BASE COUNT 408 a 459 c 388 g 339 t
ORIGIN
1 gagaggaaca tgaactgacg agtaaacatg tatggaaatt attctcactt catgaagttt
61 cccgcaggct atggaggctc ccctggccac actggctcta catccatgag cccatcagca
121 gccttgtcca cagggaagcc aatggacagc caccccagct acacagatac cccagtgagt
181 gccccacgga ctctgagtgc agtggggacc cccctcaatg ccctgggctc tccatatcga
241 gtcatcacct ctgccatggg cccaccctca ggagcacttg cagcgcctcc aggaatcaac
301 ttggttgccc cacccagctc tcagctaaat gtggtcaaca gtgtcagcag ttcagaggac
361 atcaagccct taccagggct tcccgggatt ggaaacatga actacccatc caccagcccc
421 ggatctctgg ttaaacacat ctgtgctatc tgtggagaca gatcctcagg aaagcactac
481 ggggtataca gttgtgaagg ctgcaaaggg ttcttcaaga ggacgataag gaaggacctc
541 atctacacgt gtcgggataa taaagactgc ctcattgaca agcgtcagcg caaccgctgc
601 cagtactgtc gctatcagaa gtgccttgtc atgggcatga agagggaagc tgtgcaagaa
661 gaaagacaga ggagccgaga gcgagctgag agtgaggcag aatgtgctac cagtggtcat
721 gaagacatgc ctgtggagag gattctagaa gctgaacttg ctgttgaacc aaagacagaa
781 tcctatggtg acatgaatat ggagaactcg acaaatgacc ctgttaccaa catatgtcat
841 gctgctgaca agcagctttt caccctcgtt gaatgggcca agcgtattcc ccacttctct
901 gacctcacct tggaggacca ggtcattttg cttcgggcag ggtggaatga attgctgatt
961 gcctctttct cccaccgctc agtttccgtg caggatggca tccttctggc cacgggttta
1021 catgtccacc ggagcagtgc ccacagtgct ggggtcggct ccatctttga cagagttcta
1081 actgagctgg tttccaaaat gaaagacatg cagatggaca agtcggaact gggatgcctg
1141 cgagccattg tactctttaa cccagatgcc aagggcctgt ccaacccctc tgaggtggag
1201 actctgcgag agaaggttta tgccaccctt gaggcctaca ccaagcagaa gtatccggaa
1261 cagccaggca ggtttgccaa gctgctgctg cgcctcccag ctctgcgttc cattggcttg
1321 aaatgcctgg agcacctctt cttcttcaag ctcatcgggg acacccccat tgacaccttc
1381 ctcatggaga tgttggagac cccgctgcag atcacctgag ccccaccagc cacagcctcc
1441 ccacccagga tgacccctgg gcaggtgtgt gtggaccccc accctgcact ttcctccacc
1501 tcccaccctg acccccttcc tgtccccaaa atgtgatgct tataataaag aaaacctttc
1561 tacaaaaaaa aaaaaaaaaa aaaaaccgga attc
//