LOCUS HSU38260 1427 bp mRNA linear HUM 17-JAN-1997
DEFINITION Human islet cell autoantigen ICAp69 mRNA, complete cds.
ACCESSION U38260
VERSION U38260.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1427)
AUTHORS Gaedigk,R., Karges,W., Hui,M.F., Scherer,S.W. and Dosch,H.M.
TITLE Genomic organization and transcript analysis of ICAp69, a target
antigen in diabetic autoimmunity
JOURNAL Genomics 38 (3), 382-391 (1996)
PUBMED 8975715
REFERENCE 2 (bases 1 to 1427)
AUTHORS Gaedigk,R.
TITLE Direct Submission
JOURNAL Submitted (11-OCT-1995) Roger Gaedigk, Immunology, The Hospital for
Sick Children, 555 University Ave., Toronto, Ontario M5G 1X8,
Canada
FEATURES Location/Qualifiers
source 1..1427
/db_xref="H-InvDB:HIT000219544"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IS13"
/cell_type="islet"
CDS 170..943
/note="autoantigen in type 1 diabetes"
/codon_start=1
/product="islet cell autoantigen ICAp69"
/protein_id="AAC50936.1"
/translation="MSGHKCSYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKK
EDEHVVASDADLDAKLELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQG
FQDKTRAGKMMQATGKALCFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRME
QCRTEYRGALLWMKDVSQELDPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDL
LGASRCNLLSHMLATYQLAWDQWQGPRNLKVLTKMTCCC"
BASE COUNT 429 a 328 c 347 g 323 t
ORIGIN
1 attaacccag gagatggggg tcgaggagag accccgggga gtagagagag agaaactcac
61 tccccgagtc cccgaccctc cccaagcaag gttataatat aacttatcct ctcatgcttt
121 tttcctgccc cttctcccca aatcatcaac aatagaagaa gaagaaaaca tgtcaggaca
181 caaatgcagt tatccctggg acttacagga tcgatatgct caagataagt cagttgtaaa
241 taagatgcaa cagaaatatt gggagacgaa gcaggccttt attaaagcca cagggaagaa
301 ggaagatgaa catgttgttg cctctgacgc ggacctggat gccaagctag agctgtttca
361 ttcaattcag agaacctgtc tggacttatc gaaagcaatt gtactctatc aaaagaggat
421 atgtttcttg tctcaagaag aaaacgaact gggaaaattt cttcgatccc aaggtttcca
481 agataaaacc agagcaggaa agatgatgca agcgacagga aaggccctct gcttttcttc
541 ccagcaaagg ttggccttac gaaatccttt gtgtcgattt caccaagaag tggagacttt
601 tcggcatcgg gccatctcag atacttggct gacggtgaac cgcatggaac agtgcaggac
661 ggaatataga ggagcactat tatggatgaa ggacgtgtct caggagcttg atccagacct
721 ctacaagcaa atggagaagt tcaggaaggt acaaacacaa gtgcgccttg caaaaaaaaa
781 ctttgacaaa ttgaagatgg atgtttgtca aaaagtggat cttcttggag cgagcagatg
841 caatctcttg tctcacatgc tagcaacata ccagcttgcc tgggaccagt ggcagggacc
901 ccggaacctg aaggtgctga caaagatgac ctgctgctgt tgagtgagat cttcaatgct
961 tcctccttgg aagagggcga gttcagcaaa gagtgggccg ctgtgtttgg agacggccaa
1021 gtgaaggagc cagtgcccac tatggccctg ggagagccag accccaaggc ccagacaggc
1081 tcaggtttcc ttccttcgca gcttttagac caaaatatga aagacttaca ggcctcgcta
1141 caagaacctg ctaaggctgc ctcagacctg actgcctggt tcagcctctt cgctgacctc
1201 gacccactct caaatcctga tgctgttggg aaaaccgata aagaacacga attgctcaat
1261 gcatgaatct gtacccttcg ggagggcact cacatgccgc ccccagcagc tcccctgggg
1321 gctagcagaa gtataaagtg atcagtatgc tgttttaata attatgtgcc attttaataa
1381 aatgaaaggg tcaacggccc tgtttatatt ggtataaaaa aaaaaaa
//