LOCUS HSU37408 2109 bp mRNA linear HUM 06-OCT-1998
DEFINITION Homo sapiens phosphoprotein CtBP mRNA, complete cds.
ACCESSION U37408
VERSION U37408.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (sites)
AUTHORS Boyd,J.M., Subramanian,T., Schaeper,U., La Regina,M., Bayley,S. and
Chinnadurai,G.
TITLE A region in the C-terminus of adenovirus 2/5 E1a protein is
required for association with a cellular phosphoprotein and
important for the negative modulation of T24-ras mediated
transformation, tumorigenesis and metastasis
JOURNAL EMBO J. 12 (2), 469-478 (1993)
PUBMED 8440238
REFERENCE 2 (bases 50 to 1369)
AUTHORS Schaeper,U., Boyd,J.M., Verma,S., Uhlmann,E., Subramanian,T. and
Chinnadurai,G.
TITLE Molecular cloning and characterization of a cellular phosphoprotein
that interacts with a conserved C-terminal domain of adenovirus E1A
involved in negative modulation of oncogenic transformation
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 92 (23), 10467-10471 (1995)
PUBMED 7479821
REMARK Erratum:[Proc Natl Acad Sci U S A 1998 Nov 24;95(24):14584]
REFERENCE 3 (bases 1 to 2109)
AUTHORS Chinnadurai,G.
TITLE Direct Submission
JOURNAL Submitted (29-SEP-1995) G. Chinnadurai, Institute for Molecular
Virology, St. Louis University Health Sciences Center, 3681 Park
Avenue, St. Louis, MO 63110, USA
REFERENCE 4 (bases 1 to 2109)
AUTHORS Elangovan,B. and Chinnadurai,G.
TITLE Direct Submission
JOURNAL Submitted (06-OCT-1998) G. Chinnadurai, Institute for Molecular
Virology, St. Louis University Health Sciences Center, 3681 Park
Avenue, St. Louis, MO 63110, USA
REMARK Sequence update by submitter
COMMENT On Oct 6, 1998 this sequence version replaced gi:1063637.
FEATURES Location/Qualifiers
source 1..2109
/db_xref="H-InvDB:HIT000219514"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone_lib="B-cell library of S. Elledge"
CDS 50..1372
/function="interacts with C-terminus of Adenovirus E1A"
/experiment="experimental evidence, no additional details
recorded"
/codon_start=1
/product="phosphoprotein CtBP"
/protein_id="AAC62822.1"
/translation="MGSSHLLNKGLPLGVRPPIMNGPLHPRPLVALLDGRDCTVEMPI
LKDVATVAFCDAQSTQEIHEKVLNEAVGALMYHTITLTREDLEKFKALRIIVRIGSGF
DNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRATWLHQALREGTRVQSVE
QIREVASGAARIRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGVERALGLQ
RVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALA
QALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAARE
IRRAITGRIPDSLKNCVNKDHLTAATHWASMDPAVVHPELNGAAYRYPPGVVGVAPTG
IPAAVEGIVPSAMSLSHGLPPVAHPPHAPSPGQTVKPEADRDHASDQL"
BASE COUNT 402 a 638 c 638 g 431 t
ORIGIN
1 cgcgcagcgc gccggagtgg tcggggcccg cggccgctcg cgcctctcga tgggcagctc
61 gcacttgctc aacaagggcc tgccgcttgg cgtccgacct ccgatcatga acgggcccct
121 gcacccgcgg cccctggtgg cattgctgga tggccgggac tgcacagtgg agatgcccat
181 cctgaaggac gtggccactg tggccttctg cgacgcgcag tccacgcagg agatccatga
241 gaaggtcctg aacgaggctg tgggggccct gatgtaccac accatcactc tcaccaggga
301 ggacctggag aagttcaaag ccctccgcat catcgtccgg attggcagtg gttttgacaa
361 catcgacatc aagtcggccg gggatttagg cattgccgtc tgcaacgtgc ccgcggcgtc
421 tgtggaggag acggccgact cgacgctgtg ccacatcctg aacctgtacc ggcgggccac
481 ctggctgcac caggcgctgc gggagggcac acgagtccag agcgtcgagc agatccgcga
541 ggtggcgtcc ggcgctgcca ggatccgcgg ggagaccttg ggcatcatcg gacttggtcg
601 cgtggggcag gcagtggcgc tgcgggccaa ggccttcggc ttcaacgtgc tcttctacga
661 cccttacttg tcggatggcg tggagcgggc gctggggctg cagcgtgtca gcaccctgca
721 ggacctgctc ttccacagcg actgcgtgac cctgcactgc ggcctcaacg agcacaacca
781 ccacctcatc aacgacttca ccgtcaagca gatgagacaa ggggccttcc tggtgaacac
841 agcccggggt ggcctggtgg atgagaaggc gctggcccag gccctgaagg agggccggat
901 ccgcggcgcg gccctggatg tgcacgagtc ggaacccttc agctttagcc agggccctct
961 gaaggatgca cccaacctca tctgcacccc ccatgctgca tggtacagcg agcaggcatc
1021 catcgagatg cgagaggagg cggcacggga gatccgcaga gccatcacag gccggatccc
1081 agacagcctg aagaactgtg tcaacaagga ccatctgaca gccgccaccc actgggccag
1141 catggacccc gccgtcgtgc accctgagct caatggggct gcctataggt accctccggg
1201 cgtggtgggc gtggccccca ctggcatccc agctgctgtg gaaggtatcg tccccagcgc
1261 catgtccctg tcccacggcc tgccccctgt ggcccacccg ccccacgccc cttctcctgg
1321 ccaaaccgtc aagcccgagg cggatagaga ccacgccagt gaccagttgt agcccgggag
1381 gagctctcca gcctcggcgc ctggggcagc gggcccggaa accctcgacc agagtgtgtg
1441 agagcatgtg tgtggtggcc cctggcactg cagagactgg tccgggctgt caggagggcg
1501 ggagggcgca gcgctgggcc tcgtgtcgct tgtcgtccgt cctgtgggcg ctctgccctg
1561 tgtccttcgc gttcctcgtt aagcagaaga agtcagtagt tattctccca tgaacgttct
1621 tgtctgtgta cagtttttag aacattacaa aggatctgtt tgcttagctg tcaacaaaaa
1681 gaaaacctga aggagcattt ggaagtcaat ttgaggtttt tttttttggt tttttttttt
1741 ttgtattttg gaacgtgccc cagaatgagg cagttggcaa acttctcagg acaatgaatc
1801 ttcccgtttt tctttttatg ccacacagtg cattgttttt tctacctgct tgtcttattt
1861 ttagcataat ttagaaaaac aaaacaaagg ctgtttttcc taattttggc atgaaccccc
1921 ccttgttcca aaatgaagac ggcatcatca cgaagcagct ccaaaaggaa aagcttggca
1981 ggtgccctcg tcctggggac gtggagggtg gcacggtccc cgcctgcacc agtgccgtcc
2041 tgctgatgtg gtaggctagc aatattttgg ttaaaatcat gtttgtggcc gaacgggccc
2101 ctgcacccg
//