LOCUS HSU35234 6363 bp mRNA linear HUM 08-DEC-1995
DEFINITION Human protein tyrosine phosphatase sigma mRNA, complete cds.
ACCESSION U35234
VERSION U35234.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6363)
AUTHORS Pulido,R., Serra-Pages,C., Tang,M. and Streuli,M.
TITLE The LAR/PTP delta/PTP sigma subfamily of transmembrane
protein-tyrosine-phosphatases: multiple human LAR, PTP delta, and
PTP sigma isoforms are expressed in a tissue-specific manner and
associate with the LAR-interacting protein LIP.1
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 92 (25), 11686-11690 (1995)
PUBMED 8524829
REFERENCE 2 (bases 1 to 6363)
AUTHORS Pulido,R., Serra-Pages,C., Tang,M. and Streuli,M.
TITLE Direct Submission
JOURNAL Submitted (31-AUG-1995) Michel Streuli, Tumor Immunology,
Dana-Farber Cancer Institute, 44 Binney Street, Boston, MA 02115,
USA
FEATURES Location/Qualifiers
source 1..6363
/db_xref="H-InvDB:HIT000219418"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 109..5955
/note="HPTPs"
/codon_start=1
/product="protein tyrosine phosphatase sigma"
/protein_id="AAC50299.1"
/translation="MAPTWGPGMVSVVGPMGLLVVLLVGGCAAEEPPRFIKEPKDQIG
VSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLRIQPLRTPRDE
NVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASG
NPDPEITWFKDFLPVDPSASNGRIKQLRSETFESTPIRGALQIESSEETDQGKYECVA
TNSAGVRYSSPANLYVRELREVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYV
KWMQGAEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEAVAQITVKSLPKA
PGTPMVTENTATSITITWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGL
SPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEP
VEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVG
DGPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQESIIKYELLFREGDHG
REVGRTFDPTTSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQD
VKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQIL
LEALEKWTQYRITTVAHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVL
WLGPVPGRQHGQIRGYQVHYVRMEGAEGRGPPRIKDVMLADAQWETDDTAEYEMVITN
LQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRPTLSVQQTPEGSLLARWEPPA
GTAEDQVLGYRLQFGREDSTPLATLEFPPSEDRYTASGVHKGATYVFRLAARSRGGLG
EEAAEVLSIPEDTPRGHPQILEAAGNASAGTVLLRWLPPVPAERNGAIVKYTVAVREA
GALGPARETELPAAAEPGAENAVTLQGLKPDTAYDLQVRAHTRRGPGPFSPPVRYRTF
LRDQVSPKNFKVKMIMKTSVLLSWEFPDNYNSPTPYKIQYNGLTLDVDGRTTKKLITH
LKPHTFYNFVLTNRGSSLGGLQQTVTAWTAFNLLNGKPSVAPKPDADGFIMVYLPDGQ
SPVPVQSYFIVMVPLRKSRGGQFLTPLGSPEDMDLEELIQDISRLQRRTVRHSRQLEV
PRPYIAARFSVLPPTFHPGDQKQYGGFDNRGLEPGHRYVLFVLAVLQKSEPTFAASPF
SDPFQLDNPDPQPIVDGEEGLIWVIGPVLAVVFIICIVIAILLYKNKPDSKRKDSEPR
TKCLLNNADLAPHHPKDPVEMRRINFQTPDSGLRSPLREPGFHFESMLSHPPIPIADM
AEHTERLKANDSLKLSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHFRVILQ
PIEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLE
EKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQF
TAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIK
PEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKL
AQVEPGEHVTGMELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQP
IRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLRE
MGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFT
DWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERM
RYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFDHYAT"
BASE COUNT 1301 a 2073 c 1921 g 1068 t
ORIGIN
1 cggccagcct ccagacgttg ccccatctga cgctcggctc gaggcctctc tgtgagggac
61 cggggggcca tccccctcca gggcggagat cggaggtcgc tgccaagcat ggcgcccacc
121 tggggccctg gcatggtgtc tgtggttggt cccatgggcc tccttgtggt cctgctcgtt
181 ggaggctgtg cagcagaaga gccccccagg tttatcaaag aacccaagga ccagatcggc
241 gtgtcggggg gtgtggcctc tttcgtgtgt caggccacgg gtgaccccaa gccacgagtg
301 acctggaaca agaagggcaa gaaggtcaac tctcagcgct ttgagacgat tgagtttgat
361 gagagtgccg gggcagtgct gaggatccag ccgctgagga caccgcggga tgaaaacgtg
421 tacgagtgtg tggcccagaa ctcggttggg gagatcacag tccatgccaa gcttactgtc
481 ctccgagagg accagctgcc ctctggcttc cccaacatcg acatgggccc acagttgaag
541 gtggtggagc ggacacggac agccaccatg ctctgtgcag ccagcggcaa ccctgaccct
601 gagatcacct ggttcaagga cttcctgcct gtggatccta gtgccagcaa tggacgcatc
661 aaacagctgc gatcagaaac ctttgaaagc actccgattc gaggagccct gcagattgaa
721 agcagtgagg aaaccgacca gggcaaatat gagtgtgtgg ccaccaacag cgccggcgtg
781 cgctactcct cacctgccaa cctctacgtg cgagagcttc gagaagtccg ccgcgtggcc
841 ccgcgcttct ccatcctgcc catgagccac gagatcatgc cagggggcaa cgtgaacatc
901 acctgcgtgg ccgtgggctc gcccatgcca tacgtgaagt ggatgcaggg ggccgaggac
961 ctgacccccg aggatgacat gcccgtgggt cggaacgtgc tggaactcac agatgtcaag
1021 gactcggcca actacacctg cgtggccatg tccagcctgg gcgtcattga ggcggttgct
1081 cagatcacgg tgaaatctct ccccaaagct cccgggactc ccatggtgac tgagaacaca
1141 gccaccagca tcaccatcac gtgggactcg ggcaacccag atcctgtgtc ctattacgtc
1201 atcgaatata aatccaagag ccaagacggg ccgtatcaga ttaaagagga catcaccacc
1261 acacgttaca gcatcggcgg cctgagcccc aactcggagt acgagatctg ggtgtcggcc
1321 gtcaactcca tcggccaggg gccccccagc gagtccgtgg tcacccgcac aggcgagcag
1381 gccccggcca gcgcgccgcg gaacgtgcaa gcccggatgc tcagcgcgac caccatgatt
1441 gtgcagtggg aggagccggt ggagcccaac ggcctgatcc gcggctaccg cgtctactac
1501 accatggaac cggagcaccc cgtgggcaac tggcagaagc acaacgtgga cgacagcctg
1561 ctgaccaccg tgggcagcct gctggaggac gagacctaca ccgtgcgggt gctcgccttc
1621 acctccgtcg gcgacgggcc cctctcggac cccatccagg tcaagacgca gcagggagtg
1681 ccgggccagc ccatgaacct gcgggccgag gccaggtcgg agaccagcat cacgctgtcc
1741 tggagccccc cgcggcagga gagtatcatc aagtacgagc tcctcttccg ggaaggcgac
1801 catggccggg aggtgggaag gaccttcgac ccgacgactt cctacgtggt ggaggacctg
1861 aagcccaaca cggagtacgc cttccgcctg gccgcccgct cgccgcaggg cctgggcgcc
1921 ttcacccccg tggtgcggca gcgcacgctg cagtccaaac cgtcagcccc ccctcaagac
1981 gttaaatgtg tcagcgtgcg ctccacggcc attttggtaa gttggcgccc gccgccgccg
2041 gaaacgcaca acggggccct ggtgggctac agcgtccgct accgaccgct gggctcagag
2101 gacccggaac ccaaggaggt gaacggcatc cccccgacca ccactcagat cctgctggag
2161 gccttggaga agtggaccca gtaccgcatc acgactgtcg ctcacacaga ggtgggacca
2221 gggcccgaga gctcacccgt ggtcgtccgc accgacgagg atgtgcccag cgcgccgccg
2281 cggaaggtgg aggcggaggc gctcaacgcc acggccatcc gcgtgctgtg gctcggccct
2341 gtgcccggcc ggcagcacgg ccagatccgc ggctaccagg tccactacgt gcgcatggag
2401 ggcgccgagg gccgcgggcc gccgcgcatc aaggacgtca tgctggccga tgcccagtgg
2461 gagacggatg acacggccga atatgagatg gtcatcacaa acttgcagcc tgagaccgcg
2521 tactccatca cggtagccgc ctacaccatg aagggcgatg gcgctcgcag caaacccaag
2581 gtggttgtga ccaagggagc agtgttgggc cgcccaaccc tgtcggtgca gcagaccccc
2641 gagggcagcc tgctggcacg ctgggagccc ccggctggca ccgcggagga ccaggtgctg
2701 ggctaccgcc tgcagtttgg ccgtgaggac tcgacgcccc tggccaccct ggagttcccg
2761 ccctccgagg accgctacac ggcatcaggc gtgcacaagg gggccacgta tgtgttccgg
2821 cttgcggccc ggagccgggg cggcctgggc gaggaggcag ccgaggtcct gagcatcccg
2881 gaggacacgc cccgtggcca cccgcagatt ttggaagccg ccggcaacgc ctcggccggg
2941 accgtccttc tccgctggct gccacccgtg cccgccgagc gcaacggggc catcgtcaaa
3001 tacacggtgg ccgtgcgtga ggccggtgcc ctgggccctg cccgagagac tgagctgccg
3061 gcagcggctg agccgggcgc ggagaacgcc gtcacgctgc agggcctgaa gcccgacacg
3121 gcctatgacc tccaagtgcg agcccacacg cgccggggcc ctggcccctt cagccccccc
3181 gtccgctacc ggacgttcct gcgggaccaa gtctcgccca agaacttcaa ggtgaaaatg
3241 atcatgaaga catcagttct gctcagctgg gagttccctg acaactacaa ctcacccaca
3301 ccctacaaga tccagtacaa tgggctcaca ctggatgtgg atggccgtac caccaagaag
3361 ctcatcacgc acctcaagcc ccacaccttc tacaactttg tgctgaccaa tcgcggcagc
3421 agcctgggcg gcctccagca gacggtcacc gcctggactg ccttcaacct gctcaacggc
3481 aagcccagcg tcgcccccaa gcctgatgct gacggcttca tcatggtgta tcttcctgac
3541 ggccagagcc ccgtgcctgt ccagagctat ttcattgtga tggtgccact gcgcaagtct
3601 cgtggaggcc aattcctgac cccgctgggt agcccagagg acatggatct ggaagagctc
3661 atccaggaca tctcacggct acagaggcgc accgtgcggc actcgcgtca gctggaggtg
3721 ccccggccct atattgcagc tcgcttctct gtgctgccac ccacgttcca tcccggcgac
3781 cagaagcagt atggcggctt cgataaccgg ggcctggagc ccggccaccg ctatgtcctc
3841 ttcgtgcttg ccgtgcttca gaagagcgag cctacctttg cagccagtcc cttctcagac
3901 cccttccagc tggataaccc ggacccccag cccatcgtgg atggcgagga ggggcttatc
3961 tgggtgatcg ggcctgtgct ggccgtggtc ttcataatct gcattgtcat tgctatcctg
4021 ctctacaaga acaaacccga cagtaaacgc aaggactcag aaccccgcac caaatgcctc
4081 ctgaacaatg ccgacctcgc ccctcaccac cccaaggacc ctgtggaaat gagacgcatt
4141 aacttccaga ctccagattc aggcctcagg agccccctca gggagccggg gtttcacttt
4201 gaaagcatgc ttagccaccc gccaattccc atcgcagaca tggcggagca cacggagcgg
4261 ctcaaggcca acgacagcct caagctctcc caggagtatg agtccatcga ccctggacag
4321 cagttcacat gggaacattc caacctggaa gtgaacaagc cgaagaaccg ctatgccaac
4381 gtcatcgcct atgaccactt ccgtgtcatc ctccagccca ttgaaggcat catgggcagt
4441 gattacatca atgccaacta tgtggacggc taccggcgtc agaacgcgta cattgccacg
4501 caggggccgc tgcctgagac ctttggggac ttctggcgta tggtgtggga gcagcggtcg
4561 gcgaccatcg tcatgatgac gcggctggag gagaagtcac ggatcaagtg tgatcagtat
4621 tggcccaaca gaggcacgga gacctacggc ttcatccagg tcacgttgct agataccatc
4681 gagctggcca cattctgcgt caggacattc tctctgcaca agaatggctc cagtgagaaa
4741 cgcgaggtcc gccagttcca gtttacggcg tggccggacc atggcgtgcc cgaataccca
4801 acgcccttcc tggctttcct gcggagagtc aagacctgca acccgccaga tgccggcccc
4861 atcgtggttc actgcagtgc cggtgtgggc cgcacaggct gctttatcgt catcgacgcc
4921 atgcttgagc ggatcaagcc agagaagaca gtcgatgtct atggccacgt gacgctcatg
4981 aggtcccagc gcaactacat ggtgcagacg gaggaccagt acagcttcat ccacgaggcc
5041 ctgctggagg ccgtgggctg tggcaacaca gaagtgcccg cacgcagcct ctatgcctac
5101 atccagaagc tggcccaggt ggagcctggc gaacacgtca ctggcatgga actcgagttc
5161 aagcggctgg ctaactccaa ggcccacacg tcacgcttca tcagtgccaa tctgccttgt
5221 aacaagttca agaaccgcct ggtgaacatc atgccctatg agagcacacg ggtctgtctg
5281 caacccatcc ggggtgtgga gggctctgac tacatcaacg ccagcttcat tgatggctat
5341 aggcagcaga aggcctacat cgcgacacag gggccgctgg cggagaccac ggaagacttc
5401 tggcgcatgc tgtgggagaa caattcgacg atcgtggtga tgctgaccaa gctgcgggag
5461 atgggccggg agaagtgtca ccagtactgg ccggccgagc gctctgcccg ctaccagtac
5521 tttgtggtag atccgatggc agaatacaac atgcctcagt atatcctgcg agagttcaag
5581 gtcacagatg cccgggatgg ccagtcccgg actgtccggc agttccagtt cacagactgg
5641 ccggaacagg gtgtgccaaa gtcgggggag ggcttcatcg acttcattgg ccaagtgcat
5701 aagactaagg agcagtttgg ccaggacggc cccatctctg tccactgcag tgccggcgtg
5761 ggcaggacgg gcgtcttcat cacgcttagc atcgtgctgg agcggatgcg gtatgaaggc
5821 gtggtggaca tctttcagac ggtgaagatg ctacgaaccc agcggccggc catggtgcag
5881 acagaggatg agtaccagtt ctgttaccag gcggcactgg agtacctcgg aagctttgac
5941 cactatgcaa cctaaagcca tggtcccccc caggcccgac accactggcc ccggatgcct
6001 ctgcccctcc cgggcggacc tcctgaggcc tggaccccca gtgggcaggg caggaggtgg
6061 cagcggcagc agctgtgttt ttctgcacca tttccgagga cgacgcatcc cctcgagccc
6121 ccccaccggc cccggccgcc ccagcgacct ccctggcacc ggccgccgcc ttcaaatact
6181 tggcacattc ctcctttcct tccaattcca aaaccagatt ccggggtggg gggtgggggg
6241 atggtgagca aataggagtg ctccccagaa ccagaggagg gtggggcaca gaccatagac
6301 ggacccctcg tcctccccca gcggtggtag ggggacccgg ggggctcctc cccgctctgc
6361 acc
//