LOCUS HSU33749 2336 bp mRNA linear HUM 17-APR-1997
DEFINITION Human thyroid transcription factor-1 (TTF-1) mRNA, complete cds.
ACCESSION U33749
VERSION U33749.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2336)
AUTHORS Hamdan,H., Liu,H., Jones,C., deLemos,R. and Minoo,P.
TITLE Characterization of TTF-1 transcripts in human lung identifies an
additional exon
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 2336)
AUTHORS Hamdan,H.
TITLE Direct Submission
JOURNAL Submitted (11-AUG-1995) Hasnah Hamdan, University of Southern
California, Pediatrics, Division of Basic Research, 1801 E.
Marengo, Rm 1G-1, Los Angeles, CA 90033, USA
COMMENT On Apr 17, 1997 this sequence version replaced gi:1072047.
FEATURES Location/Qualifiers
source 1..2336
/db_xref="H-InvDB:HIT000219326"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="lung"
/clone_lib="Lambda DR2 5' stretch library of Clontech,
Palo Alto, CA."
/dev_stage="fetus"
gene 1..2336
/gene="TTF-1"
CDS 342..1457
/gene="TTF-1"
/codon_start=1
/product="thyroid transcription factor-1"
/protein_id="AAB52381.1"
/translation="MSMSPKHTTPFSVSDILSPLEESYKKVGMEGGGLGAPLAAYRQG
QAAPPTAAMQQHAVGHHGAVTAAYHMTAAGVPQLSHSAVGGYCNGNLGNMSELPPYQD
TMRNSASGPGWYGANPDPRFPAISRFMGPASGMNMSGMGGLGSLGDVSKNMAPLPSAP
RRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKR
QAKDKAAQQQLQQDSGGGGGGGGTGCPQQQQAQQQSPRRVAVPVLVKDGKPCQAGAPA
PGAASLQGHAQQQAQHQAQAAQAAAAAISVGSGGAGLGAHPGHQPGSAGQSPDLAHHA
ASPAALQGQVSSLSHLNSSGSDYGTMSCSTLLYGRTW"
polyA_site 2336
/gene="TTF-1"
/note="35 A nucleotides"
BASE COUNT 523 a 712 c 644 g 457 t
ORIGIN
1 gaaacttaaa ggtgtttacc ttgtcatcag catgtaagct aattatctcg ggcaagatgt
61 aggcttctat tgtcttgttg ctttagcgct tacgccccgc ctctggtggc tgcctaaaac
121 ctggcgccgg gctaaaacaa acgcgaggca gcccccgagc ctccactcaa gccaattaag
181 gaggactcgg tccactccgt tacgtgtaca tccaacaaga tcggcgttaa ggtaacacca
241 gaatatttgg caaagggaga aaaaaaaagc agcgaggctt cgccttcccc ctctcccttt
301 tttttcctcc tcttccttcc tcctccagcc gccgccgaat catgtcgatg agtccaaagc
361 acacgactcc gttctcagtg tctgacatct tgagtcccct ggaggaaagc tacaagaaag
421 tgggcatgga gggcggcggc ctcggggctc cgctggcggc gtacaggcag ggccaggcgg
481 caccgccaac agcggccatg cagcagcacg ccgtggggca ccacggcgcc gtcaccgccg
541 cctaccacat gacggcggcg ggggtgcccc agctctcgca ctccgccgtg gggggctact
601 gcaacggcaa cctgggcaac atgagcgagc tgccgccgta ccaggacacc atgaggaaca
661 gcgcctctgg ccccggatgg tacggcgcca acccagaccc gcgcttcccc gccatctccc
721 gcttcatggg cccggcgagc ggcatgaaca tgagcggcat gggcggcctg ggctcgctgg
781 gggacgtgag caagaacatg gccccgctgc caagcgcccc acgccggaag cgccgggtgc
841 tcttctcgca ggcgcaggtg tacgagctgg agcgacgctt caagcaacag aagtacctgt
901 cggcgccgga gcgcgagcac ctggccagca tgatccacct gacgcccacg caggtcaaga
961 tctggttcca gaaccaccgc tacaaaatga agcgccaggc caaggacaag gcggcgcagc
1021 agcaactgca gcaggacagc ggcggcggcg ggggcggcgg gggcaccggg tgcccgcagc
1081 agcaacaggc tcagcagcag tcgccgcgac gcgtggcggt gccggtcctg gtgaaagacg
1141 gcaaaccgtg ccaggcgggt gcccccgcgc cgggcgccgc cagcctacaa ggccacgcgc
1201 agcagcaggc gcagcaccag gcgcaggccg cgcaggcggc ggcagcggcc atctccgtgg
1261 gcagcggtgg cgccggcctt ggcgcacacc cgggccacca gccaggcagc gcaggccagt
1321 ctccggacct ggcgcaccac gccgccagcc ccgcggcgct gcagggccag gtatccagcc
1381 tgtcccacct gaactcctcg ggctcggact acggcaccat gtcctgctcc accttgctat
1441 acggtcggac ctggtgagag gacgccgggc cggccctagc ccagcgctct gcctcaccgc
1501 ttccctcctg cccgccacac agaccaccat ccaccgctgc tccacgcgct tcgacttttc
1561 ttaacaacct ggccgcgttt agaccaagga acaaaaaaac cacaaaggcc aaactgctgg
1621 acgtctttct ttttttcccc ccctaaaatt tgtgggtttt ttttttaaaa aaaagaaaat
1681 gaaaaacaac caagcgcatc caatctcaag gaatctttaa gcagagaagg gcataaaaca
1741 gctttggggt gtcttttttt ggtgattcaa atgggttttc cacgctaggg cggggcacag
1801 attggagagg gctctgtgct gacatggctc tggactctaa agaccaaact tcactctggg
1861 gacactctgc cagcaaagag gactcgcttg taaataccag gatttttttt ttttttttga
1921 agggaggacg ggagctgggg agaggaaaga gtcttcaaca taacccactt gtcactgaca
1981 caaaggaagt gccccctccc cggcaccctc tggccgccta ggctcagcgg cgaccgccct
2041 ccgcgaaaat agtttgttta atgtgaactt gtagctgtaa aacgctgtca aaagttggac
2101 taaatgccta gtttttagta atctgtacat tttgttgtaa aaagaaaaac cactcccagt
2161 ccccagccct tcacattttt tatgggcatt gacaaatctg tgtatattat ttggcagttt
2221 ggtatttgcg gcgtcagtct ttttctgttg taacttatgt agatatttgg cttaaatata
2281 gttcctaaga agcttctaat aaattataca aattaaaaag attctttttc tgatta
//