LOCUS HSU31110 3312 bp mRNA linear HUM 02-APR-1996
DEFINITION Human alternatively spliced trp-1 protein and unspliced trp-1
protein (trp-1) mRNA, complete cds.
ACCESSION U31110
VERSION U31110.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3312)
AUTHORS Zhu,X., Chu,P.B., Peyton,M. and Birnbaumer,L.
TITLE Molecular cloning of a widely expressed human homologue for the
Drosophila trp gene
JOURNAL FEBS Lett. 373 (3), 193-198 (1995)
PUBMED 7589464
REFERENCE 2 (bases 1 to 3312)
AUTHORS Zhu,X., Chu,P.B. and Birnbaumer,L.
TITLE Direct Submission
JOURNAL Submitted (06-JUL-1995) Xi Zhu, Anesthesiology, UCLA School of
Medicine, 10833 Le Conte Ave., Los Angeles, CA 90095-1778, USA
FEATURES Location/Qualifiers
source 1..3312
/db_xref="H-InvDB:HIT000219124"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..3312
/gene="trp-1"
mRNA 1..3312
/gene="trp-1"
/product="unspliced trp-1 protein"
mRNA join(1..1062,1165..3312)
/gene="trp-1"
/product="alternatively spliced trp-1 protein"
/note="This alternatively spliced mRNA is often found in
clones from several libraries"
CDS 736..3117
/gene="trp-1"
/note="This is the predicted product from the complete
human trp-1 mRNA; similar to Drosophila transient
receptor, Swiss-Prot Accession Number P19334; Method:
conceptual translation supplied by author"
/codon_start=1
/product="unspliced trp-1 protein"
/protein_id="AAA93251.1"
/translation="MMAALYPSTDLSGASSSSLPSSPSSSSPNEVMALKDVREVKEEN
TLNEKLFLLACDKGDYYMVKKILEENSSGDLNINCVDVLGRNAVTITIENENLDILQL
LLDYGCQSADALLVAIDSEVVGAVDILLNHRPKRSSRPTIVKLMERIQNPEYSTTMDV
APVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFRLDIYR
CLASPALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLLAQA
RNSRELEVILNHTSSDEPLDKRGLLEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNTV
WFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGA
SYFTFLLLLNLYSLVYNEDKKNTMGPALERIDYLLILWIIGMIWSDIKRLWYEGLEDF
LEESRNQLSFVMNSLYLATFALKVVAHNKFHDFADRKDWDAFHPTLVAEGLFAFANVL
SYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTSK
EQKDCVGIFCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGEELQSFVGAV
IVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPF
NIIPSPKTICYMISSLSKWICSHTSKGKVKRQNSLKEWRNLKQKRDENYQKVMCCLVH
RYLTSMRQKMQSTDQATVENLNELRQDLSKFRNEIRDLLGFRTSKYAMFYPRN"
CDS join(736..1062,1165..3117)
/gene="trp-1"
/note="This is a shorter human trp-1 product; similar to
Drosophila transient receptor, Swiss-Prot Accession Number
P19334; Method: conceptual translation supplied by author"
/codon_start=1
/product="alternatively spliced trp-1 protein"
/protein_id="AAA93252.1"
/translation="MMAALYPSTDLSGASSSSLPSSPSSSSPNEVMALKDVREVKEEN
TLNEKLFLLACDKGDYYMVKKILEENSSGDLNINCVDVLGRNAVTITIENENLDILQL
LLDYGCQKLMERIQNPEYSTTMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCE
CTLCSAKNKKDSLRHSRFRLDIYRCLASPALIMLTEEDPILRAFELSADLKELSLVEV
EFRNDYEELARQCKMFAKDLLAQARNSRELEVILNHTSSDEPLDKRGLLEERMNLSRL
KLAIKYNQKEFVSQSNCQQFLNTVWFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCY
LIAPKSQFGRIIHTPFMKFIIHGASYFTFLLLLNLYSLVYNEDKKNTMGPALERIDYL
LILWIIGMIWSDIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKFHDFA
DRKDWDAFHPTLVAEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLG
MFLLVLFSFTIGLTQLYDKGYTSKEQKDCVGIFCEQQSNDTFHSFIGTCFALFWYIFS
LAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDK
EWKFARAKLWLSYFDDKCTLPPPFNIIPSPKTICYMISSLSKWICSHTSKGKVKRQNS
LKEWRNLKQKRDENYQKVMCCLVHRYLTSMRQKMQSTDQATVENLNELRQDLSKFRNE
IRDLLGFRTSKYAMFYPRN"
BASE COUNT 884 a 700 c 791 g 937 t
ORIGIN
1 gggacgatta ttaggaacta gtcagttgca aagctcatta tgatggtatt actatgaaga
61 agattattac aaatgcatgg gctgtgacga taacgttgta gatgtggtcg ttacccagaa
121 ggttgcctgg ctggcccagc tcggctcgaa taaggaggct tagggctgtg cctaggactc
181 cagctcatgc gccgaataat aggtatagtg ttccaatgtc tttgtggttt gtagagaata
241 gtcaacggtc ggcgaacatc tcctcggagc gcagctgggc cagcggttcc cacagccctg
301 gagcccaacg tgcgcagaag cgcctcttgg agctcctctc ccacagatct ctcgtcctct
361 tcctgggcta ggccgcccca ggcgcgggcc ctgcgactcc tggcacggcc ccgtgctcgg
421 ctgccgccct ggcgcgcgcc acactgtcgt ccccggacgg gcgcggaccg gctcggccgg
481 ggcgccggcg gctggggagg ggtcgctggc cccggggccg cgcatgcgcc gccaccaact
541 tggggctgtc agtggagggc gagtgctggt tctcagggga ggcgacgcct tcgggccaac
601 gggcctcgag ccgaggcagc agtgggaacg actcatcctt tttccagccc tggggcgtgg
661 ctggggtcgg ggtcggggtc ggggccggtg ggggccccgc ccccgtctcc tggcctgccc
721 ccttcatggg ccgcgatgat ggcggccctg tacccgagca cggacctctc gggcgcctcc
781 tcctcctccc tgccttcctc tccatcctct tcctcgccga acgaggtgat ggcgctgaag
841 gatgtgcggg aggtgaagga ggagaatacg ctgaatgaga agcttttctt gctggcgtgc
901 gacaagggtg actattatat ggttaaaaag attttggagg aaaacagttc aggtgacttg
961 aacataaatt gcgtagatgt gcttgggaga aatgctgtta ccataactat tgaaaacgaa
1021 aacttggata tactgcagct tcttttggac tacggttgtc agtctgcaga tgcacttttg
1081 gtggcaatcg actctgaagt agtgggagct gttgatatac tacttaatca tcgaccaaaa
1141 cgatcatcaa gaccaactat agtaaaacta atggaacgaa ttcagaatcc tgagtattca
1201 acaactatgg atgttgcacc tgtcatttta gctgctcatc gtaacaacta tgaaattctt
1261 acaatgctct taaaacagga tgtatctcta cccaagcccc atgcagttgg ctgtgaatgc
1321 acattgtgtt ctgcaaaaaa caaaaaggat agcctccggc attccaggtt tcgtcttgat
1381 atatatcgat gtttggccag tccagctcta ataatgttaa cagaggagga tccaattctg
1441 agagcatttg aacttagtgc tgatttaaaa gaactaagtc ttgtggaggt ggaattcagg
1501 aatgattatg aggaactagc ccggcaatgt aaaatgtttg ctaaggattt acttgcacaa
1561 gcccggaatt ctcgtgaatt ggaagttatt ctaaaccata cgtctagtga cgagcctctt
1621 gacaaacggg gattattaga agaaagaatg aatttaagtc gtctaaaact tgctatcaaa
1681 tataaccaga aagagtttgt ctcccagtct aactgccagc agttcctgaa cactgtttgg
1741 tttggacaga tgtcgggtta ccgacgcaag cccacctgta agaagataat gactgttttg
1801 acagtaggca tcttttggcc agttttgtca ctttgttatt tgatagctcc caaatctcag
1861 tttggcagaa tcattcacac accttttatg aaatttatca ttcatggagc atcatatttc
1921 acatttctgc tgttgcttaa tctatactct cttgtctaca atgaggataa gaaaaacaca
1981 atggggccag cccttgaaag aatagactat cttcttattc tgtggattat tgggatgatt
2041 tggtcagaca ttaaaagact ctggtatgaa gggttggaag actttttaga agaatctcgt
2101 aatcaactca gttttgtcat gaattctctt tatttggcaa cctttgccct caaagtggtt
2161 gctcacaaca agtttcatga ttttgctgat cggaaggatt gggatgcatt ccatcctaca
2221 ctggtggcag aagggctttt tgcatttgca aatgttctaa gttatcttcg tctctttttt
2281 atgtatacaa ccagctctat cttgggtcca ttacagattt caatgggaca gatgttacaa
2341 gattttggaa aatttcttgg gatgtttctt cttgttttgt tttctttcac aattggactg
2401 acacaactgt atgataaagg atatacttca aaggagcaga aggactgtgt aggcatcttc
2461 tgtgaacagc aaagcaatga taccttccat tcgttcattg gcacctgctt tgctttgttc
2521 tggtatattt tctccttagc gcatgtggca atctttgtca caagatttag ctatggagaa
2581 gaactgcagt cctttgtggg agctgtcatt gttggtacat acaatgtcgt ggttgtgatt
2641 gtgcttacca aactgctggt ggcaatgctt cataaaagct ttcagttgat agcaaatcat
2701 gaagacaaag aatggaagtt tgctcgagca aaattatggc ttagctactt tgatgacaaa
2761 tgtacgttac ctccaccttt caacatcatt ccctcaccaa agactatctg ctatatgatt
2821 agtagcctca gtaagtggat ttgctctcat acatcaaaag gcaaggtcaa acggcaaaac
2881 agtttaaagg aatggaggaa tttgaaacag aagagagatg aaaactatca aaaagtgatg
2941 tgctgcctag tgcatcgtta cttgacttcc atgagacaga agatgcaaag tacagatcag
3001 gcaactgtgg aaaatctaaa cgaactgcgc caagatctgt caaaattccg aaatgaaata
3061 agggatttac ttggctttcg gacttctaaa tatgctatgt tttatccaag aaattaacca
3121 ttttctaaat catggagcga ataattttca ataacagatc caaaagacta tattgcataa
3181 cttgcaatga aattaatgag atatatattg aaataaagaa ttatgtaaaa gccgttcctt
3241 taaaatattt atagcattaa atatatgtta tgtaaagtgt gtatatagaa ttagtttttt
3301 aaaccttctg tt
//