LOCUS HSU29589 3906 bp DNA linear HUM 23-JUL-1995
DEFINITION Human m3 muscarinic acetylcholine receptor (CHRM3) gene, complete
cds.
ACCESSION U29589
VERSION U29589.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3906)
AUTHORS Bonner,T.I., Young,A.C., Brann,M.R. and Buckley,N.J.
TITLE Cloning and expression of the human and rat m5 muscarinic
acetylcholine receptor genes
JOURNAL Neuron 1 (5), 403-410 (1988)
PUBMED 3272174
REFERENCE 2 (bases 1 to 3906)
AUTHORS Bonner,T.I.
TITLE Direct Submission
JOURNAL Submitted (20-JUN-1995) Tom I. Bonner, Lab of Cell Biology, NIMH,
National Institutes of Health, Bldg. 36, Room 3A-17, Bethesda, MD
20892-4090, USA
FEATURES Location/Qualifiers
source 1..3906
/db_xref="H-InvDB:HIT000398690"
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1q43-44"
/clone_lib="partial HaeIII-AluI genomic library of R.M.
Lawn, E.F. Fritsch, R.C. Parker, G. Blake, and T.
Maniatis, Cell 15, 1157-1174, 1978."
intron <1..182
exon 183..3713
/note="based on comparison to the rat cDNA rather than a
human cDNA"
gene 202..1974
/gene="CHRM3"
CDS 202..1974
/gene="CHRM3"
/codon_start=1
/product="m3 muscarinic acetylcholine receptor"
/protein_id="AAA70337.1"
/translation="MTLHNNSTTSPLFPNISSSWIHSPSDAGLPPGTVTHFGSYNVSR
AAGNFSSPDGTTDDPLGGHTVWQVVFIAFLTGILALVTIIGNILVIVSFKVNKQLKTV
NNYFLLSLACADLIIGVISMNLFTTYIIMNRWALGNLACDLWLAIDYVASNASVMNLL
VISFDRYFSITRPLTYRAKRTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPP
GECFIQFLSEPTITFGTAIAAFYMPVTIMTILYWRIYKETEKRTKELAGLQASGTEAE
TENFVHPTGSSRSCSSYELQQQSMKRSNRRKYGRCHFWFTTKSWKPSSEQMDQDHSSS
DSWNNNDAAASLENSASSDEEDIGSETRAIYSIVLKLPGHSTILNSTKLPSSDNLQVP
EEELGMVDLERKADKLQAQKSVDDGGSFPKSFSKLPIQLESAVDTAKTSDVNSSVGKS
TATLPLSFKEATLAKRFALKTRSQITKRKRMSLVKEKKAAQTLSAILLAFIITWTPYN
IMVLVNTFCDSCIPKTFWNLGYWLCYINSTVNPVCYALCNKTFRTTFKMLLLCQCDKK
KRRKQQYQQRQSVIFHKRAPEQAL"
polyA_site 3714
/note="based on comparison to the rat cDNA rather than a
human cDNA"
BASE COUNT 1073 a 897 c 875 g 1061 t
ORIGIN
1 atcgatgtct gtctgcccta gactccactt atttaaaata agagaatgaa cttgatgttt
61 ggcttcatag agattcagca ccctgtaata ggccttccat gtcttttaac gtatgtaatg
121 caaagaacaa acaaataaag gcagaaattt ttctaactct gtctcttctc tctttccccc
181 agactatgtc agagagtcac aatgaccttg cacaataaca gtacaacctc gcctttgttt
241 ccaaacatca gctcctcctg gatacacagc ccctccgatg cagggctgcc cccgggaacc
301 gtcactcatt tcggcagcta caatgtttct cgagcagctg gcaatttctc ctctccagac
361 ggtaccaccg atgaccctct gggaggtcat accgtctggc aagtggtctt catcgctttc
421 ttaacgggca tcctggcctt ggtgaccatc atcggcaaca tcctggtaat tgtgtcattt
481 aaggtcaaca agcagctgaa gacggtcaac aactacttcc tcttaagcct ggcctgtgcc
541 gatctgatta tcggggtcat ttcaatgaat ctgtttacga cctacatcat catgaatcga
601 tgggccttag ggaacttggc ctgtgacctc tggcttgcca ttgactacgt agccagcaat
661 gcctctgtta tgaatcttct ggtcatcagc tttgacagat acttttccat cacgaggccg
721 ctcacgtacc gagccaaacg aacaacaaag agagccggtg tgatgatcgg tctggcttgg
781 gtcatctcct ttgtcctttg ggctcctgcc atcttgttct ggcaatactt tgttggaaag
841 agaactgtgc ctccgggaga gtgcttcatt cagttcctca gtgagcccac cattactttt
901 ggcacagcca tcgctgcttt ttatatgcct gtcaccatta tgactatttt atactggagg
961 atctataagg aaactgaaaa gcgtaccaaa gagcttgctg gcctgcaagc ctctgggaca
1021 gaggcagaga cagaaaactt tgtccacccc acgggcagtt ctcgaagctg cagcagttac
1081 gaacttcaac agcaaagcat gaaacgctcc aacaggagga agtatggccg ctgccacttc
1141 tggttcacaa ccaagagctg gaaacccagc tccgagcaga tggaccaaga ccacagcagc
1201 agtgacagtt ggaacaacaa tgatgctgct gcctccctgg agaactccgc ctcctccgac
1261 gaggaggaca ttggctccga gacgagagcc atctactcca tcgtgctcaa gcttccgggt
1321 cacagcacca tcctcaactc caccaagtta ccctcatcgg acaacctgca ggtgcctgag
1381 gaggagctgg ggatggtgga cttggagagg aaagccgaca agctgcaggc ccagaagagc
1441 gtggacgatg gaggcagttt tccaaaaagc ttctccaagc ttcccatcca gctagagtca
1501 gccgtggaca cagctaagac ttctgacgtc aactcctcag tgggtaagag cacggccact
1561 ctacctctgt ccttcaagga agccactctg gccaagaggt ttgctctgaa gaccagaagt
1621 cagatcacta agcggaaaag gatgtccctg gtcaaggaga agaaagcggc ccagaccctc
1681 agtgcgatct tgcttgcctt catcatcact tggaccccat acaacatcat ggttctggtg
1741 aacacctttt gtgacagctg catacccaaa accttttgga atctgggcta ctggctgtgc
1801 tacatcaaca gcaccgtgaa ccccgtgtgc tatgctctgt gcaacaaaac attcagaacc
1861 actttcaaga tgctgctgct gtgccagtgt gacaaaaaaa agaggcgcaa gcagcagtac
1921 cagcagagac agtcggtcat ttttcacaag cgcgcacccg agcaggcctt gtagaatgag
1981 gttgtatcaa tagcagtgac aaaacgcaca catcaaccca cagaccttag gaggaggaag
2041 gcgagggcgg ggtgacttct ggtgatgata aaaatggttt tatcacccag atgtgaaaga
2101 agctgcctgt ttactgatcc attgaataaa cccattttaa tagaaaaagt caataccaat
2161 tcagcaaaaa gaaaaaaaaa acatactact gaatataaag aaatttattc tgaaatagac
2221 tttacgtgtt tttttcttaa agaggagaaa aatattgctt gacggcaatt atatacccaa
2281 agtgatttgc ctgggtcctt taattcccat tagctttgga atctcagatg agcatagctg
2341 acccagttcc cacattcttc ccaaggatcc aaaagtggga atccagaccc caagtggaac
2401 actgcaggct tacgaatctg tggttccaaa attatttcat acgttgcaaa gctgaatctt
2461 cttgtcccaa tagagcttcc tgtcttttct ttggtgtgtt gttaaactct atttgtggac
2521 ttgattcttg attcttgcaa agtactgttt tgtgcagttc aagtttcgta caaataaaat
2581 acttaagtat atatatatgt gtgagttctg cacgcacaca catagtgtat ataatatcat
2641 gggaaacact gaactggcaa attattcctg caacatacgc tttcagtact ttggtaactg
2701 aagttctcta ggatcctaat gcaacattaa cgtgaaataa gcccagtgta atgtttttgc
2761 aaaccagggc tgttttccac agagagcagc caggccttcc cagcaggtct gtgcagagcg
2821 gacaggctcg tgagtcagct gagcgccgtg gcttcgccag acttggtgtt aagcaacctc
2881 ctttgttgat gtctcaacag agctaaatcg gggcccctct gagctcaaag aatgaaccac
2941 atccacacgt ttgaatttaa tcatctaaat ctgaatgttt cagaacaaaa tttctgctat
3001 ctaaactgct tgaaactcaa taatagtgtc acgtttgaat gtcatacaca gcaatatata
3061 tatatgtgta tatatatata tatggcaaag caaaaaaaaa aacatggtaa gagagaatga
3121 aggagaacat tgtgtttgat tcttgctgaa tggcaccttc tcaaagaaaa tagggcttgc
3181 acctttgtta atcagctgtg gccagtgctt tctggtgttc attgtgtaac cttcacccag
3241 gaataggtga ggttttagga agttacatgt cctctgaaga aagaattaca ctctgaaaag
3301 taatgcttca aattgatttc cttacctttt gggaaaaaaa aaaaattgtt tttttgcatt
3361 ctcccttgaa ttgaccaaaa tgttaactgt ttcatttggg gaggggatgg ggtgctgcca
3421 tcattgtcgt tgttgttgct gctgtagctg ttggggtttc ttttcctgtt gccggggctg
3481 tttggggaga gggaggggag ggaggtggga gggccgcgga gatatcttcc cctttgtaca
3541 gggcattctg tgttgtgaac ccagagctgg gtagaagctg cttttgtatt cagtgtgagg
3601 tggtgtttac agacgacttt gacaacagta gaagtgtact cagtggtgtc tgtgtatctg
3661 aactatttaa tttcgtgtta tgtttatatg cagaaatatt tatggatact acaccaagtg
3721 tttatttatt gttgataaat atgactcttc agtcgtcagc catggtgtcc tttcaaatga
3781 ttctttaagg tccacttgag caatgaatag agtatattgg agctttcctg tggctaagaa
3841 gaagaaacat gtcatcctgt tgccatcacc aagcacctaa ctctttctag gtaataaaaa
3901 gtcaac
//