LOCUS AH003120 9344 bp DNA linear HUM 10-JUN-2016
DEFINITION Homo sapiens chromosome 12 high-mobility group phosphoprotein
isoform I-C (HMGIC) gene, complete cds.
ACCESSION AH003120 U28750 U28751 U28752 U28753 U28754
VERSION AH003120.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (sites)
AUTHORS Manfioletti,G., Giancotti,V., Bandiera,A., Buratti,E., Sautiere,P.,
Cary,P., Crane-Robinson,C., Coles,B. and Goodwin,G.H.
TITLE cDNA cloning of the HMGI-C phosphoprotein, a nuclear protein
associated with neoplastic and undifferentiated phenotypes
JOURNAL Nucleic Acids Res. 19 (24), 6793-6797 (1991)
PUBMED 1762909
REFERENCE 2 (bases 1 to 9344)
AUTHORS Schoenmakers,E.F., Mols,R., Wanschura,S., Kools,P.F., Geurts,J.M.,
Bartnitzke,S., Bullerdiek,J., van den Berghe,H. and Van de Ven,W.J.
TITLE Identification, molecular cloning, and characterization of the
chromosome 12 breakpoint cluster region of uterine leiomyomas
JOURNAL Genes Chromosomes Cancer 11 (2), 106-118 (1994)
PUBMED 7529547
REFERENCE 3 (bases 1 to 9344)
AUTHORS Schoenmakers,E.F.P.M., Wanschura,S., Mols,R., Bullerdiek,J., Van
den Berghe,H. and Van de Ven,W.J.M.
TITLE Recurrent rearrangements in the high mobility group protein gene
HMGI-C in a variety of benign mesenchymal tumors
JOURNAL Unpublished
REFERENCE 4 (bases 1 to 9344)
AUTHORS Schoenmakers,E.F.P.M.
TITLE Direct Submission
JOURNAL Submitted (08-JUN-1995) Eric F.P.M. Schoenmakers, Laboratory for
Molecular Oncology, Center for Human Genetics, Herestraat 49, B3000
Leuven, Belgium
COMMENT On or before Jun 10, 2016 this sequence version replaced U28750.1,
U28751.1, U28752.1, U28753.1, U28754.1, AH003120.1.
FEATURES Location/Qualifiers
source 1..9344
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/chromosome="12"
/map="12q15"
gene 1447..8269
/gene="HMGIC"
exon 1447..2368
/gene="HMGIC"
/note="Recurrently rearranged in a variety of benign
mesenchymal tumors; Method: conceptual translation
supplied by author."
/number=1
CDS join(2258..2368,3148..3234,3785..3835,4641..4673,
5296..5343)
/gene="HMGIC"
/codon_start=1
/product="high-mobility group phosphoprotein isoform I-C"
/protein_id="AAA68614.1"
/translation="MSARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPS
PKRPRGRPKGSKNKSPSKAAQKKAEATGEKRPRGRPRKWPQQVVQKKPAQEETEETSS
QESAEED"
gap 2702..2801
/estimated_length=unknown
exon 3148..3234
/gene="HMGIC"
/number=2
gap 3442..3541
/estimated_length=unknown
exon 3785..3835
/gene="HMGIC"
/number=3
gap 4162..4261
/estimated_length=unknown
exon 4641..4673
/gene="HMGIC"
/number=4
gap 4794..4893
/estimated_length=unknown
exon 5296..8269
/gene="HMGIC"
/number=5
regulatory 8143..8147
/regulatory_class="polyA_signal_sequence"
/gene="HMGIC"
/note="polyA_signal"
BASE COUNT 2378 a 2141 c 1884 g 2496 t
ORIGIN
1 ctgcagagca ctcaacgtgc agcaaagtgt cccagctctg caaagggcag ctggaaatgg
61 atttaaaatg gcaacgcgga ccaatcagcg ctgccgcnca aaagcagaca tttacacgcg
121 cctcctccac atgcacagcg gaacctngcg gtgcctaact cctgcttagg gctgcaaagt
181 aggcgttttt attccacggt ggtctgtatc tttgaaaaaa ataaattctt ccccaggtga
241 aagtttttat tttggaatta gtccaaaata attttgggtg tgatgtgtga aaatctgaac
301 ctaatttttt cagagttttg tgttattcaa ggatgaaaag aggtacattt aaaaatgtac
361 tccacctttt aaaaacggac tgtggncatt atggtgttca cataactcag aacagcccag
421 gccataaaat taggacttgg cagaaagaga gttctcaggc agaaggttaa atcgaggtaa
481 actgaaggga gagttgggca gtgagtgcaa ttgtggtgtt aggaatctac aaggtgccct
541 ttaccctggg aacatcggat tcccggggag ggggatgggg agggaacttc ggttgcctct
601 agtctttcct ggagaaaaaa gttcaatgaa gaagctgggg cgctctgtgt gtgcacattg
661 tttgcatgtg tctgcgaatg tgcatgtcta tctgcgtgcc tgtgtgtatg tgtgtgtgtg
721 taaatgcggg tgtttaccag cgcatgaatg ccccccgtgt ccacgtgtat ctgcgtgcat
781 gtgcttacac gcgtgttcgt gtgtatctgc atgcatgtct ccgtgtatgt gcgcgctcgc
841 ccgcgcgcag gctctgtggt gagggcattc cgaggcggag tacggctgtc aggggacctc
901 tcccactcca ctgcagtccc ttcccactca cagtgaaccg gtgcgctgcc tgaggtgcag
961 cctagacgct tcctgcaaag tgttggctcg gcacggtaga ggcgcaggta aaggccaagc
1021 cccgaaacgt ggctccggga cagtcacgtt cccgcgcctt cccaggacaa ctgcccaggg
1081 gtgacctcga gaggcgggtg gagctaggcc cacggcgagc cagcccggga tcccggcctg
1141 tcctttaacc cgccgccggg cgggagcacg tgagcggggc tccgggtggc acccgggcgc
1201 cgccgccgcc gaggcagttg tatttcgaac gctgcctctg gctagcagcc aggcgccttg
1261 gctcggcggt ccgcctggcc tccctcctcc tcatactttt cttcctgcgc aaccccctcc
1321 cctttatccg cccacgatta gaggtgggca ctccccccac caccaccccc tccccaagcg
1381 caagcgcgtg cacgcacaca caccacacac actcacactc acacacactc acacacactc
1441 atcccacttg aatcttgggg caggaactca gaaaacttcc agcccgggca gcgcgcgctt
1501 ggtgcaagac tcaggagcta gcagcccgtc cccctccgac tctccggtgc cgccgctgcc
1561 tgctcccgcc accctaggag gcgcggtgcc acccactact ctgtcctctg cctgtgctcc
1621 gtgcccgacc ctatcccggc ggagtctccc catcctcctt tgctttccga ctgcccaagg
1681 cactttcaat ctcaatctct tctctctctc tctctctctc tctgtctctc tctctctctc
1741 tctctctctc tctctcgcag ggtgggggga agaggaggag gaattctttc cccgcctaac
1801 atttcaaggg acacaattca ctccaagtct cttccctttc caagccgctt ccgaagtgct
1861 cccggtgccc gcaactcctg atcccaaccc gcgagaggag cctctgcgac ctcaaagcct
1921 ctcttccttc tccctcgctt ccctcctcct cttgctacct ccacctccac cgccacctcc
1981 acctccggca cccacccacc gccgccgccg ccaccggcag cgcctcctcc tctcctcctc
2041 ctcctcccct cttctctttt tggcagccgc tggacgtccg gtgttgatgg tggcagcggc
2101 ggcagcctaa gcaacagcag ccctcgcagc ccgccagctc gcgctcgccc cgccggcgtc
2161 cccagcccta tcacctcatc tcccgaaagg tgctgggcag ctccggggcg gtcgaggcga
2221 agcggctgca gcggcggtag cggcggcggg aggcaggatg agcgcacgcg gtgagggcgc
2281 ggggcagccg tccacttcag cccagggaca acctgccgcc ccagcgcctc agaagagagg
2341 acgcggccgc cccaggaagc agcagcaagt cagtacgagg gcgcggtggg ggcaccagcc
2401 caccccgtcc ccactgccgg ggcccagaca cnnnnnnggc ggccggagtg cgggagccca
2461 gtcgccgcgg ccgtcgcaca cngcccgccg gcngnccggg ngggagcggc gcagacccca
2521 cgagtgcgcc gcgcggcccc ggggcgccan caaccctccg ggcngggagg tggggagccg
2581 cggcgggcgg cccggggaag gcnggaggtg gggtcgggcg aagcgcgtcc tcggactttc
2641 gctattgtgc acggccccga gtggcgcggn gtcgcccagt gactggaagc gaccgggatc
2701 cnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
2761 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nattcctatg agttgcnaaa
2821 atgatagccc ctgtaaactt taccccttaa aagtatatga ctttctttct agaacatgcc
2881 tcttcagtct ttgttaccat tttaggtttg aagtagaatc tagttttcat atacaaaata
2941 gagtttcctc tttgaaccct tgcattaaaa gtatagttat ttcccctttc tgtaaactct
3001 gtaccatcat catccattta tgcttgaact gaacgtgttc caacagctct tttgagcagc
3061 acatgcagaa aatatagcta aagagtcagg gtcaatttct ttcagacatt cttgccacaa
3121 cagcattttt ttttccctca caattaggaa ccaaccggtg agccctctcc taagagaccc
3181 aggggaagac ccaaaggcag caaaaacaag agtccctcta aagcagctca aaaggtgaga
3241 tttctcaagt caagctctcc taacttcatc aatgactgac tacaggagcc tgcctgtaac
3301 tttcccattc taactccgca gccaggaatt tgtcccaact gggtaacaca agactcattt
3361 cttacatttn acattagtta gatgcgagtt aacctttttt gtaagcagat gctcagcata
3421 aaaaagttta ttgaaggtac tnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
3481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
3541 ncttttaggg cgaaggggtt gcatagatac ccnctttaca tcatgnaatg aagaagaaat
3601 ctacncagaa atgtggaaaa anattaacct tagaggagac gaagtttgtt aaaaaaaaca
3661 aaaannnnaa aaccgatacg tcaatngcaa agcagaacat tcttacntca aatgtgtccc
3721 ttggtgcagt acttataaac aatgtcaggt agaaaactat aatgacttcc tttttcattt
3781 gcagaaagca gaagccactg gagaaaaacg gccaagaggc agacctagga aatgggtgag
3841 taataagata taatttttct tctttttttt aaaganaaat ttctgttgta ttaaatgaga
3901 aaagttttat ttcgtcgatt acatgaattt ccaacttctg gtttgatgaa tctttgaaag
3961 ggttaagtca agagacaaat tatcatcact tcctaccact aggctccagg tgtttacgta
4021 gaacactttt ctttcctgaa ggtggactca tttttctatc tcttatctaa catcaaaaga
4081 ggctccactc ttccttcaaa tagggtaanc aatgagatga tttgttcagt agntttgagt
4141 aactaaagtt aanagggtnt tnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
4201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
4261 nctgcagcct tgacctttct tggcccaggt gatccttcca tttaggcctc tgagtagctg
4321 ggactacagt tgcaacgcca ccacaccctg ttaatttttg tatgtttgta gagagagggt
4381 ttcaccatgt tgcccagcct ggtctacaac tcctgggctc aagccatccg tccgcctctg
4441 cctcccaaag cgctgggatt ataagcgtga gccaccatgc ctggccaagt ataaacactt
4501 ttaacattgg atataccagt tgaactttat actttcctct ttcctttgca gacaagtatc
4561 tgtatttaaa atatgtacac ctaatttttt ctataatgta tattttcttt taaaatatat
4621 ctttttcttt tcctccttag ccacaacaag ttgttcagaa gaagcctgct caggtaagac
4681 atagtcatta atttttttct cccaattaat ataaaaagtg aaatatgtac tgaaaaatgt
4741 ccccaaacta aaccttattt cgcattttct tacttttggt tatcgtcctg cagnnnnnnn
4801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
4861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnggatccc cctaactcta tttttcttgt
4921 gtgccggttt ttaaaactga tgaatggcat gctgtcggga aaaatttatc cattcctact
4981 ttttttctaa ttggtgagta agcgtgcatt gccctgacat tctctggaca gcaaacaatt
5041 gaatttgctg accagccgcc atgatgtcaa gccttaagtc aacagtggct aatgaccgct
5101 ctgggaaaaa acaacacctt gattcctcaa ttacggttta agaagccctg ggaatgaggg
5161 ctcgccagtc atcgtcatcc tcttttgagg caagcataat gtgctgtgga aacaggttac
5221 ctctgcactg ttggcangag cagcccacac agtataacga ttgagcgtca tggctgtgcc
5281 ntttgtgtgt tccaggagga aactgaagag acatcctcac aagagtctgc cgaagaggac
5341 tagggggcgc aacgttcgat ttctacctca gcagcagttg gatcttttga agggagaaga
5401 cactgcagtg accacttatt ctgtattgcc atggtctttc cactttcatc tggggtgggg
5461 tggggtgggg tgggggaggg gggggtgggg tggggagaaa tcacataacc ttaaaaagga
5521 ctatattaat caccttcttt gtaatccctt cacagtccca ggtttagtga aaaactgctg
5581 taaacacagg ggacacagct taacaatgca acttttaatt actgttttct tttttcttaa
5641 cctactaata gtttgttgat ctgataagca agagtgggcg ggtgagaaaa accgaattgg
5701 gtttagtcaa tcactgcact gcatgcaaac aagaaacgtg tcacacttgt gacgtcgggc
5761 attcatatag gaagaacgcg gtgtgtaaca ctgtgtacac ctcaaatacc accccaaccc
5821 actccctgta gtgaatcctc tgtttagaac accaaagata aggactagat actactttct
5881 ctttttcgta taatcttgta gacacttact tgatgatttt taacttttta tttctaaatg
5941 agacgaaatg ctgatgtatc ctttcattca gctaacaaac tagaaaaggt tatgttcatt
6001 tttcaaaaag ggaagtaagc aaacaaatat tgccaactct tctatttatg gatatcacac
6061 atatcagcag gagtaataaa tttactcaca gcacttgttt tcaggacaac acttcatttt
6121 caggaaatct acttcctaca gagccaaaat gccatttagc aataaataac acttgtcagc
6181 ctcagagcat ttaaggaaac tagacaagta aaattatcct ctttgtaatt taatgaaaag
6241 gtacaacaga ataatgcatg atgaactcac ctaattatga ggtgggagga gcgaaatcta
6301 aatttctttt gctatagtta tacatcaatt taaaaagcaa aaaaaaaaag gggggggcaa
6361 tctctctctg tgtctttctc tctctctctc cctctccctc tctcttttca tgtgtatcag
6421 tttccatgaa agacctgaat accacttacc tcaaattaag catatgtgtt acttcaagta
6481 atacgttttg acataagatg gttgaccaag gtgcttttct tcggcttgag ttcaccatct
6541 cttcattcaa actgcacttt tagccagaga tgcaatatat ccccactact caatactacc
6601 tctgaatgtt acaacgaatt tacagtctag tacttattac atgctgctat acacaagcaa
6661 tgcaagaaaa aaacttactg ggtaggtgat tctaatcatc tgcagttctt tttgtacact
6721 taattacagt taaagaagca atctccttac tgtgtttcag catgactatg tatttttcta
6781 tgttttttta attaaaaatt tttaaaatac ttgtttcagc ttctctgcta gatttctaca
6841 ttaacttgaa aattttttaa ccaagtcgct cctaggttct taaggataat tttcctcaat
6901 cacactacac atcacacaag atttgactgt aatatttaaa tattaccctc caagtctgta
6961 cctcaaatga attctttaag gagatggact aattgacttg caaagaccta cctccagact
7021 tcaaaaggaa tgaacttgtt acttgcagca ttcatttgtt ttttcaatgt ttgaaatagt
7081 tcaaactgca gctaacccta gtcaaaacta tttttgtaaa agacatttga tagaaaggaa
7141 cacgttttta catacttttg caaaataagt aaataataaa taaaataaag ccaaccttca
7201 aagaacttga agctttgtag gtgagatgca acaagccctg cttttgcata atgcaatcaa
7261 aaatatgtgt ttttaagatt agttgaatat aagaaaatgc ttgacaaata ttttcatgta
7321 ttttacacaa atgtgatttt tgtaatatgt ctcaaccaga tttattttaa acgcttctta
7381 tgtagagttt ttatgccttt ctctcctagt gagtgtgctg actttttaac atggtattat
7441 caactgggcc aggaggtagt ttctcatgac ggcttttgtc agtatggctt ttagtactga
7501 agccaaatga aactcaaaac catctctctt ccagctgctt cagggaggta gtttcaaagg
7561 ccacatacct ctctgagact ggcagatcgc tcactgttgt gaatcaccaa aggagctatg
7621 gagagaatta aaactcaaca ttactgttaa ctgtgcgtta aataagcaaa taaacagtgg
7681 ctcataaaaa taaaagtcgc attccatatc tttggatggg ccttttagaa acctcattgg
7741 ccagctcata aaatggaagc aattgctcat gttggccaaa catggtgcac cgagtgattt
7801 ccatctctgg taaagttaca cttttatttc ctgtatgttg tacaatcaaa acacactact
7861 acctcttaag tcccagtata cctcattttt catactgaaa aaaaaagctt gtggccaatg
7921 gaacagtaag aacatcataa aatttttata tatatagttt atttttgtgg gagataaatt
7981 ttataggact gttctttgct gttgttggtc gcagctacat aagactggac atttaacttt
8041 tctaccattt ctgcaagtta ggtatgtttg caggagaaaa gtatcaagac gtttaactgc
8101 agttgacttt ctccctgttc ctttgagtgt cttctaactt tattctttgt tctttatgta
8161 gaattgctgt ctatgattgt actttgaatc gcttgcttgt tgaaaatatt tctctagtgt
8221 attatcactg tctgttctgc acaataaaca taacagcctc tgtgatcccc atgtgttttg
8281 attcctgctc tttgttacag ttccattaaa tgagtaataa agtttggtca aaacagatca
8341 aggagggaga cactcacaag tcattttgtt gcaccccttg cacacatctt ggcacacatg
8401 tacataaagt gtgttttaca tatcatactc cttcaatcaa ctgccctgag ctcgcctttc
8461 agattttgac atttaattct acagagacaa tcttagaaga aacatgaaga acaagctgta
8521 gctccaaact acagaatttt tacttcaggc tagcacctac aaagtttgta agggaagtaa
8581 ctaatgcact agtcgtcttt gagtaacatn gnaagagatc cggaagattg aataagaaat
8641 gaaagccacg aagagtctcc tagataggag ccttttaact ctaaaaacta ctagcagagt
8701 cagaatgatt ctaccaagtt caaggtcaac ttgacactta agttgctaat tatgaataaa
8761 tctaggattt tnaaaaagct aaaactttcg gtttttacta tcaccgttgt tactcaaatt
8821 tnnttcattt agcttcttag aaggagaaat ttntttctag gaaaagcttc ctgaagtttc
8881 tcctgnacct tactgaacca gcagacagca atctgtcgct aaggaacaat agattatgaa
8941 atacaataac attattttcc tcggtttatg tctggggtta accacctatt ctgctttatc
9001 cgcagatagc gttattaaaa ttagcgggcg cgtcctcgat tatggctgca cagtctcatc
9061 ggattcgctt aattttaccg tagatctcca aaaaaacagt gccagacaat tccaacgacc
9121 ggtagcacaa gtccagccgt cccttttcag attacgttaa gtgaatgcag caaagggaca
9181 acgggggttc gggttgcatt taacggtatt gaggatgcag aaaataatac tttgttgaaa
9241 ctggatgaag gaagcaatac ggctccggtt tgggtataga aatattgacg caaatatgcg
9301 tccggtgaaa ctgantgatc ttcatgccng gatgcagtgg atcc
//