LOCUS HSU26914 3576 bp mRNA linear HUM 20-NOV-1996
DEFINITION Human ras-responsive element binding protein (RREB-1) mRNA,
complete cds.
ACCESSION U26914
VERSION U26914.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3576)
AUTHORS Thiagalingam,A., De Bustros,A., Borges,M., Jasti,R., Compton,D.,
Diamond,L., Mabry,M., Ball,D.W., Baylin,S.B. and Nelkin,B.D.
TITLE RREB-1, a novel zinc finger protein, is involved in the
differentiation response to Ras in human medullary thyroid
carcinomas
JOURNAL Mol. Cell. Biol. 16 (10), 5335-5345 (1996)
PUBMED 8816445
REFERENCE 2 (bases 1 to 3576)
AUTHORS Thiagalingam,A.
TITLE Direct Submission
JOURNAL Submitted (11-MAY-1995) Arunthathi Thiagalingam, Oncology, The
Johns Hopkins Medical Institutions, 424 North Bond Street,
Baltimore, MD 21231, USA
FEATURES Location/Qualifiers
source 1..3576
/db_xref="H-InvDB:HIT000218827"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="6"
/map="6p"
/cell_line="TT"
/tissue_type="medullary thyroid carcinoma"
gene 1..3576
/gene="RREB-1"
CDS 260..2527
/gene="RREB-1"
/note="zinc finger protein"
/codon_start=1
/product="ras-responsive element binding protein"
/protein_id="AAB19094.1"
/translation="MEPIDLSIPKNFRKGDKDLATPSEXKKPEEEAGSSEQPSPCPAP
GPSLPVTLGPSGILESPMAPAPAATPEPPAQPLQGPVQLAVPIYSSALVSSPPLVGSS
ALLSGTALLRPLRPKPPLLLPKPPVTEELPPLASIAQIISSVSSAPTLLKTKVADPGP
ASTGSNTTASDSLGGSVPKAATTATPAATTSPKESSEPPAPASSPEAASPTEQGPART
SKKRGRKRGMRSRPRANSGGVDLDSSGEFASIEKMLATTDTNKFSPFLQTAEDNTQDE
VAGAPADHHGPSDEEQGSPPEDKLLRAKRNSYTNCLQKITCPHCPRVFPWASSLQRHX
LTHTDSQSDAETAAAXGEVLDLTSRDREQPSEGATELRQVAGDAPVEQATAETASPVH
REEHGRGESHEPEEEHGTEESTGDADGGRGRVEQPEPGPGLRHQAHGLQAGGGRRRGR
PGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGATTAEEGPSPAPE
QEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTD
SPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLV
RHQRIHQKARHAKHHGKDSDKEERGEEDSENESTHSGNNAVSENEAELAPNASNHMAV
TRSRKEGLASATKDCSHREEKVTAGWPSEPGQGDLNPESPAALGQDLLEPRSKRPAHP
ILATADGASQHVGME"
BASE COUNT 835 a 1057 c 1039 g 634 t
ORIGIN
1 gaattccggg tggctgcgct gcccttggtg actgcaagcc cctcactgcc ttcctggaac
61 ccaagaacrr ctttcttcac aggggcccca cccagcctcc acctccccat gtctcgatca
121 agttggagcc cgccagtagc tttgcggtgg acttcaatga gcccctggac ttctcgcaga
181 agggcctggc ctggtccaag tgaagcagga aaacatctcc tttctgagcc cttcttccct
241 ggtcccctat gactgctcca tggagcccat cgacctgtcc atccccaaga acttcaggaa
301 aggggacaag gatttggcca ctcccagcga asscaagaag cctgaggagg aggcggggag
361 cagcgagcag ccctctccct gcccagcacc cggcccttct cttcctgtaa ctttggggcc
421 cagcggaatc ctggaaagcc ccatggcccc tgctccggcg gccaccccgg aacccccagc
481 acagcccctg cagggccctg ttcagctggc ggtcccaatc tactcctcag ccctggtcag
541 cagccctcca ctcgtgggca gctcagccct cctgagtggc acagccttgc tgcgtccact
601 gcggcccaag cccccgctgc ttttgccaaa gccccccgtg acagaagagc tgcccccgct
661 ggcctccatt gcccagatca tctcatctgt atcctcggcc cccaccctgc tgaaaaccaa
721 ggtggcggac ccagggcccg caagcactgg cagtaacacc acggcttcag acagcttagg
781 aggttctgtc cccaaagccg ccaccaccgc cacccccgct gccaccacca gcccaaaaga
841 gtctagtgag cctcccgctc cagccagcag cccagaggct gcctctccca ccgagcaggg
901 cccagcgcgg acgtcgaaga agaggggccg gaaaaggggg atgaggagcc gaccccgcgc
961 caacagcggc ggggtggacc tggactccag cggggagttt gccagcatcg agaagatgct
1021 ggccaccaca gacaccaaca agttcagtcc gtttctgcag acagcggagg acaacactca
1081 ggatgaggtg gccggagccc ctgccgacca ccatgggccc agtgatgaag agcagggcag
1141 tcccccagaa gacaagctgc tgagggccaa gcggaactcg tacaccaact gcctgcagaa
1201 gatcacctgt ccccactgtc cccgggtttt cccttgggcc agctccctac agaggcacat
1261 nctcacacac actgacagtc agtcggatgc ggagactgca gccgccncgg gcgaagtgct
1321 agacctcacc tcacgggaca gagagcagcc gtcggagggc gccactgagc tccgccaggt
1381 cgcaggggat gcgcctgtgg agcaggccac ggcggaaacg gcctcgccgg tgcaccggga
1441 agagcacggg cgtggggaga gccatgagcc ggaggaggag catggcactg aggagagcac
1501 tggggacgcc gacggcggaa gaggacgcgt cgagcaacca gagcctggac ctggacttcg
1561 ccaccaagct catggacttc aagctggcgg agggcgacgg cgaggcaggc ccgggggcgc
1621 ggcctcgcag gagcagaagc tcgcctgcga cacctgtggg aagagcttca agttcctggg
1681 caccctgagc cgccaccgga aggcgcacgg ccgccaggag cccaaggacg agaagggaga
1741 tggcgccacg actgcagagg agggscccag ccctgcccct gaacaggagg agaagccscc
1801 cgagaccccg gcagaggtgg tggagtcggc cccgggtgcc ggggaggccc cggcggaaaa
1861 gctcgcggag gagacggagg gcccctccga cggggagagc gcggccgaga aaaggtcctc
1921 agagaagagc gacgatgaca agaaaccaaa gacagactcc cccaaaagcg tggccagcaa
1981 ggcagacaag aggaagaagg tctgcagcgt gtgcaacaag cggttctggt cgctgcagga
2041 cctgacccgg cacatgcgct cccacacagg ggaaaggcca tacaaatgtc agacctgcga
2101 gcgaaccttc accttgaagc acagcctggt tcgccaccag cggatccacc agaaagccag
2161 gcatgccaaa caccacggga aggacagcga caaggaagag cggggtgagg aggacagcga
2221 gaatgagtcc acccacagcg gcaacaacgc cgtctcagag aacgaggctg agctggctcc
2281 caatgccagc aaccacatgg ctgtcacccg gagccggaag gagggcttgg ccagtgccac
2341 caaggactgc agccacaggg aggagaaggt cacggcaggg tggccgtctg agcctggcca
2401 gggtgacctt aacccagaga gcccggcggc cctggggcag gacctgctgg agccgcgcag
2461 caagaggcct gcccacccaa tcctggccac agctgatggc gcctcccagc acgtggggat
2521 ggagtgacag cctcagtccc cctcagcaca gacaaaagcc agcagagcaa agcgtctata
2581 cttcatgggg tttcctcagt gccctttggc tgttgaggag tgagagagag agagagagag
2641 agagagagag agagagagag acaagcagga gcgtggctgc tcgctcagtg ccatagcctt
2701 accgcagcct gcgcgggagg cccacagncc gtgccgattc cagtgcctta actacttacc
2761 ggatccctcc atattatcat gggtgttgta tttttccaaa atgacttctt aaacaaaaca
2821 aatattataa tgaattgtct ggagaggacc tcttcatttg agcattagcg ttattttgta
2881 ttggtgtgtg tgagcttgtt cttgtgaatc tgtgatagca ccgtttgttc tgtgagctgg
2941 aaacagaagg aaaaaacata cccttgggta cccatagcca ataactggaa gaaaatgatg
3001 tgaatttcat gtaaatgacc agaggaaaga tggataagat gataatttct taaatagaca
3061 ttttcctttt ttctttgtgc ttcatggtgg agctgtcatc tggtccttgg tattacagga
3121 tgtggttgat gaaggtttcc aatatggttt caggccaaaa ccagggaaga ttctagcttc
3181 agcctcatgt cattccagtc tgtcagcatt agacatggtc actgttcaag tttcaagaca
3241 tccattctta actatagaga agagttactc ccctggcgtc ttaacctatg gaaaacatgc
3301 acggatagga tatatttgat tgcctcctct tccctttcag tatatgtatt attaatatta
3361 ttattattat tattattatt agttcatcag tttgctgttc tctgcagtga gcagaatcaa
3421 atgggcaata tttgtcctgg gagacctgtg ccgnacccag gtccccgtgt taacgtgtgc
3481 ctgcggttgt ggttggcacc ctcgggtggt agctcttcta ctgtaatgag acaagccttt
3541 cttctgtcac tgcagaattt agaaggggng gaattc
//