LOCUS HSU25128 2641 bp mRNA linear HUM 06-JUL-1995
DEFINITION Human PTH2 parathyroid hormone receptor mRNA, complete cds.
ACCESSION U25128
VERSION U25128.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2641)
AUTHORS Usdin,T.B., Gruber,C. and Bonner,T.I.
TITLE Identification and functional expression of a receptor selectively
recognizing parathyroid hormone, the PTH2 receptor
JOURNAL J. Biol. Chem. 270 (26), 15455-15458 (1995)
PUBMED 7797535
REFERENCE 2 (bases 1 to 2641)
AUTHORS Bonner,T.I.
TITLE Direct Submission
JOURNAL Submitted (17-APR-1995) Tom I. Bonner, Lab of Cell Biology, NIMH,
Bldg. 36, Room 3A-17, Bethesda, MD 20892-4090, USA
FEATURES Location/Qualifiers
source 1..2641
/db_xref="H-InvDB:HIT000218757"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="cerebral cortex and hippocampus"
CDS 143..1795
/function="stimulates cAMP production in response to
parathyroid hormone but not parathyroid hormone-related
peptide"
/note="G protein-coupled receptor"
/codon_start=1
/product="PTH2 parathyroid hormone receptor"
/protein_id="AAC50157.1"
/translation="MAGLGASLHVWGWLMLGSCLLARAQLDSDGTITIEEQIVLVLKA
KVQCELNITAQLQEGEGNCFPEWDGLICWPRGTVGKISAVPCPPYIYDFNHKGVAFRH
CNPNGTWDFMHSLNKTWANYSDCLRFLQPDISIGKQEFFERLYVMYTVGYSISFGSLA
VAILIIGYFRRLHCTRNYIHMHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDD
PQNSIEATSVDKSQYIGCKIAVVMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYL
WGFILIGWGFPAAFVAAWAVARATLADARCWELSAGDIKWIYQAPILAAIGLNFILFL
NTVRVLATKIWETNAVGHDTRKQYRKLAKSTLVLVLVFGVHYIVFVCLPHSFTGLGWE
IRMHCELFFNSFQGFFVSIIYCYCNGEVQAEVKKMWSRWNLSVDWKRTPPCGSRRCGS
VLTTVTHSTSSQSQVAASTRMVLISGKAAKIASRQPDSHITLPGYVWSNSEQDCLPHS
FHEETKEDSGRQGDDILMEKPSRPMESNPDTEGCQGETEDVL"
regulatory 2619..2625
/regulatory_class="polyA_signal_sequence"
polyA_site 2641
BASE COUNT 670 a 564 c 623 g 784 t
ORIGIN
1 ggccggtggc ccgggcccga ccaccccagc tgcgcgtcgt tactggccac aagtttgctc
61 tgggccagcc aagttggcaa cttggaagct tctcccgggc tctggaggag ggtccctgct
121 tcttcctaca gccgttccgg gcatggccgg gctgggggcg tcgctccacg tctggggttg
181 gctaatgctc ggcagctgcc tcctggccag agcccagctg gattctgatg gcaccattac
241 tatagaggag cagattgtcc ttgtgctgaa agcgaaagta caatgtgaac tcaacatcac
301 agctcaactc caggagggag aaggtaattg tttccctgaa tgggatggac tcatttgttg
361 gcccagagga acagtgggga aaatatcggc tgttccatgc cctccttata tttatgactt
421 caaccataaa ggagttgctt tccgacactg taaccccaat ggaacatggg attttatgca
481 cagcttaaat aaaacatggg ccaattattc agactgcctt cgctttctgc agccagatat
541 cagcatagga aagcaagaat tctttgaacg cctctatgta atgtataccg ttggctactc
601 catctctttt ggttccttgg ctgtggctat tctcatcatt ggttacttca gacgattgca
661 ttgcactagg aactatatcc acatgcactt atttgtgtct ttcatgctga gagctacaag
721 catctttgtc aaagacagag tagtccatgc tcacatagga gtaaaggagc tggagtccct
781 aataatgcag gatgacccac aaaattccat tgaggcaact tctgtggaca aatcacaata
841 tatcgggtgc aagattgctg ttgtgatgtt tatttacttc ctggctacaa attattattg
901 gatcctggtg gaaggtctct acctgcataa tctcatcttt gtggctttct tttcggacac
961 caaatacctg tggggcttca tcttgatagg ctgggggttt ccagcagcat ttgttgcagc
1021 atgggctgtg gcacgagcaa ctctggctga tgcgaggtgc tgggaactta gtgctggaga
1081 catcaagtgg atttatcaag caccgatctt agcagctatt gggctgaatt ttattctgtt
1141 tctgaatacg gttagagttc tagctaccaa aatctgggag accaatgcag ttgggcatga
1201 cacaaggaag caatacagga aactggccaa atcgacactg gtcctggtcc tagtctttgg
1261 agtgcattac atcgtgttcg tatgcctgcc tcactccttc actgggctcg ggtgggagat
1321 ccgcatgcac tgtgagctct tcttcaactc ctttcagggt ttctttgtgt ctatcatcta
1381 ctgctactgc aatggagagg ttcaggcaga ggtgaagaag atgtggagtc ggtggaatct
1441 ctccgtggac tggaaaagga caccgccatg tggcagccgc agatgcggct cagtgctcac
1501 caccgtgacg cacagcacca gcagccagtc acaggtggcg gccagcacac gcatggtgct
1561 tatctctggc aaagctgcca agatcgccag cagacagcct gacagccaca tcactttacc
1621 tggctatgtc tggagtaact cagagcagga ctgcctgcca cactctttcc acgaggagac
1681 caaggaagat agtgggaggc agggagatga tattctaatg gagaagcctt ccaggcctat
1741 ggaatctaac ccagacactg aaggatgcca aggagaaact gaggatgttc tctgaatgga
1801 catttgtggc tgactttcat gggctggtcc aatggctggt tgtgtgagag ggcttggctg
1861 atactcctat gcttgagttc aaaggctgaa aattcagtta aggtgttact taataatagt
1921 ttttaggctc catgaattgg ctcctgtaaa tactaacgac atgaaaatgc aagtgtcaat
1981 ggagtagttt attaccttct attggcatca agttttcctc taaattaatg tatggtattt
2041 gctctgtgat tgttcatttt tttctgctac ttttgggtag aaaaaagatt caattgcttg
2101 gctgtagctt tctctcatat atatcaccct aaatataatg aagatctttt agtgtgtatc
2161 attttccttt tagaaactag tattctctta tttcttactt taatgtactt ctatcactgc
2221 atttattttg cctgtgcata ggagcaatta ggatctaaaa aaatatatgg gaagataaaa
2281 gatctaagaa caagtacttg ctggaaaatt agttggctgg acattgataa aataatgcat
2341 ttataacaat tacatgtgtt tttgggaaca aggaaaattt ctcaaaaaag aatatttcac
2401 acatcccttc ttttgaatgg cctctttgtg accagccaga cctcaggtct tcactctttc
2461 ttctttgtaa accatgtcat gtggaaagat ttcctcagtt agtgagcttg tgtctgcaaa
2521 ttgattttgt ttgtaatgta ttttgatagc aaatcatgct gcatctatat ctttttcttg
2581 tttgagctgt tactacattg tacatggcat gtgggatcaa ttaaaaattt gttttaaaaa
2641 t
//