LOCUS HSU24660 2074 bp mRNA linear HUM 08-NOV-1995
DEFINITION Human G protein coupled inward rectifier potassium channel 2
(hiGIRK2) mRNA, complete cds.
ACCESSION U24660
VERSION U24660.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2074)
AUTHORS Ferrer,J., Nichols,C.G., Makhina,E.N., Salkoff,L., Bernstein,J.,
Gerhard,D., Wasson,J., Ramanadham,S. and Permutt,A.
TITLE Pancreatic islet cells express a family of inwardly rectifying K+
channel subunits which interact to form G-protein-activated
channels
JOURNAL J. Biol. Chem. 270 (44), 26086-26091 (1995)
PUBMED 7592809
REFERENCE 2 (bases 1 to 2074)
AUTHORS Permutt,M.
TITLE Direct Submission
JOURNAL Submitted (12-APR-1995) M. Alan Permutt, Internal Medicine,
Washington University School of Medicine, 660 S. Euclid, St. Louis,
MO 63110, USA
FEATURES Location/Qualifiers
source 1..2074
/db_xref="H-InvDB:HIT000218748"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="pK1.8"
/cell_type="pancreatic islet"
/tissue_type="insulinoma"
gene 1..2074
/gene="hiGIRK2"
CDS 213..1484
/gene="hiGIRK2"
/note="similar to Mus musculus G protein coupled inward
rectifier K+ channel 2, encoded by Genbank Accession
Number U11859"
/codon_start=1
/protein_id="AAC50258.1"
/translation="MAKLTESMTNVLEGDSMDQDVESPVAIHQPKLPKQARDDLPRHI
SRDRTKRKIQRYVRKDGKCNVHHGNVRETYRYLTDIFTTLVDLKWRFNLLIFVMVYTV
TWLFFGMIWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVI
TDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKL
CLMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSP
LIISHEINQQSPFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGY
RFTPVLTLEDGFYEVDYNSFHETYETSTPSLSAKELAELASRAELPLSWSVSSKLNQH
AELETEEEEKNLEEQTERNGDVANLENESKV"
BASE COUNT 558 a 495 c 475 g 546 t
ORIGIN
1 atggagtctc ctaacagcct ctcggtgctg atgtgaaatt tgaccatctg attccagttt
61 ttttcttttc cttttctttt ttgcatttcc ttccctcgcc atccgtcgtg tagtgaattg
121 ttcagtcttg ctccgtttca agagaggaga tcatgattga gtgaagccac cccgtccgca
181 gccaggaaaa gcacaaagaa gaaactgcaa caatggccaa gctgacagaa tccatgacta
241 acgtcctgga gggcgactcc atggatcagg acgtcgaaag cccagtggcc attcaccagc
301 caaagttgcc taagcaggcc agggatgacc tgccaagaca catcagccga gatcggacca
361 aaaggaaaat ccagaggtac gtgaggaaag acggaaagtg caatgttcat cacggcaacg
421 tgagggagac ctatcgctac ctgaccgata tcttcaccac attagtggac ctgaagtgga
481 gattcaacct attgattttt gtcatggttt acacagtgac ctggctcttt tttggaatga
541 tctggtggtt gatcgcatac atacggggag acatggacca catagaggac ccctcctgga
601 ctccttgtgt taccaacctc aacgggttcg tctctgcttt tttattctca atagagacag
661 aaaccaccat tggttatggc taccgggtca tcacagataa atgcccggag ggaattattc
721 ttctcttaat ccaatctgtg ttggggtcca ttgtcaatgc attcatggtg ggatgcatgt
781 ttgtaaaaat ctctcaaccc aagaagaggg cagagaccct ggtcttttcc acccatgcag
841 tgatctccat gcgggatggg aaactgtgcc tgatgttccg ggtaggggac cttaggaatt
901 cccacattgt ggaggcttcc atcagagcca agttgatcaa atccaaacag acctcggagg
961 gggagttcat cccgttgaac cagacggata tcaacgtagg gtattacacg ggggatgacc
1021 gtctgtttct ggtgtcaccg ctgatcatta gccatgaaat taaccaacag agtcctttct
1081 gggagatctc caaagcccag ctgcccaaag aggaactgga aattgtggtc atcctagaag
1141 gaatggtgga agccacaggg atgacatgcc aagctcgaag ctcctacatc accagtgaga
1201 tcctgtgggg ttaccggttc acacctgtcc tgaccctgga ggatgggttc tacgaagttg
1261 actacaacag cttccatgag acctatgaga ccagcacccc atcccttagt gccaaagagc
1321 tggccgagtt agccagcagg gcagagctgc ccctgagttg gtctgtatcc agcaaactca
1381 accaacatgc agaactggag actgaagagg aagaaaagaa cctcgaagag caaacagaaa
1441 gaaatggtga tgtggcaaac ctggagaatg aatccaaagt ttagtgccct agctgggcaa
1501 acccttctct tctcccccca acacaatctt tccttgtctc tcattctctt tctttttctg
1561 tctctcttgc tttgttcttt atttgtttat atttaatttt tacatgacca gaaaacaaat
1621 cttcaaggtg taaaatatct acctgccctc tctcagttat tcagattgac aaggtagaca
1681 tggatttgat gaaagtgcaa agtgccctca tttgtggccc aagcctggtc tcctcccaaa
1741 atactacaca tccaactcct ggagatttca gttacttacc tgcatgtgtt gtacaatacc
1801 agatcactca aaaaggtgtg tcaaagattt tacctgggat atgacaagca aggtttctgg
1861 tgcctattta ttcattcagt gagacacaga gtggagccct cagttttatg gatcccaatt
1921 catttcatct actacagggt gaggtgcttg cccccatgtg ggtgtggcag ttacagggcc
1981 caggtgagct gaagacaaac cactgtacat atatatgcct tatgtaatta ttttcttttt
2041 gtaattagta ataaaaccca gcatgtacaa aagt
//