LOCUS HSU24267 2123 bp mRNA linear HUM 05-JUN-1996
DEFINITION Human pyrroline-5-carboxylate dehydrogenase (P5CDh) mRNA, short
form, complete cds.
ACCESSION U24267
VERSION U24267.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2123)
AUTHORS Hu,C.A., Lin,W.W. and Valle,D.
TITLE Cloning, characterization, and expression of cDNAs encoding human
delta 1-pyrroline-5-carboxylate dehydrogenase
JOURNAL J. Biol. Chem. 271 (16), 9795-9800 (1996)
PUBMED 8621661
REFERENCE 2 (bases 1 to 2123)
AUTHORS Hu,C.A., Lin,W. and Valle,D.L.
TITLE Direct Submission
JOURNAL Submitted (07-APR-1995) Chien-an A. Hu, Molecular Biology and
Genetics, Johns Hopkins University, PCTB802, 725 N. Wolfe St,
Baltimore, MD 21205, USA
FEATURES Location/Qualifiers
source 1..2123
/db_xref="H-InvDB:HIT000218743"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/tissue_type="retina"
/note="short form of mRNA"
gene 1..2123
/gene="P5CDh"
CDS 31..1722
/gene="P5CDh"
/EC_number="1.5.1.12"
/function="P5C degradation"
/note="Method: conceptual translation supplied by author"
/codon_start=1
/product="pyrroline-5-carboxylate dehydrogenase"
/protein_id="AAC50501.1"
/translation="MLLPAPALRRALLSRPWTGAGLRWKHTSSLKVANEPVLAFTQGS
PERDALQKALKDLKGRMEAIPCVMGDEEVWTSDVQYQVSPFNHGHKVAKFCYADKSLL
NKAIEAALAARKEWDLKPIADRAQIFLKAADMLSGPRRAEILAKTMVGQGKTVIQAEI
DAAAELIDFFRFNAKYAVELEGQQPISVPPSTNSTVYRGLEGFVAAISPFNFTAIGGN
LAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADGPLFGDTVTSS
EHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGECGGKNFHFVHRSADVESVVS
GTLRSAFEYGGQKCSACSRLYVPHSLWPQIKGRLLEEHSRIKVGDPAEDFGTFFSAVI
DAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEPCIVESKDPQEPIMKEEIFG
PVLSVYVYPDDKYKETLQLVDSTTSYGLTGAVFSQDKDVVQEATKVLRNAAGNFYIND
KSTGSIVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPLGDWSYAYMQ"
polyA_site 2123
/gene="P5CDh"
/note="16 A nucleotides"
BASE COUNT 410 a 624 c 670 g 419 t
ORIGIN
1 tccagcgaac agccccgctt ctaacccgag atgctgctgc cggcgcccgc gctccgccgc
61 gccctgctgt cccgcccctg gaccggggcc ggcctgcggt ggaagcacac ctcctccctg
121 aaggtggcca acgagcccgt cttagccttc acgcagggca gccctgagcg agatgccctg
181 caaaaggcct tgaaggacct gaagggccgg atggaagcca tcccatgcgt gatgggggat
241 gaggaggtgt ggacgtcgga cgtgcagtac caagtgtcgc cttttaacca tggacataag
301 gtggccaagt tctgttatgc agacaagagc ctgctcaaca aagccattga ggctgccctg
361 gctgcccgga aagagtggga cctgaagcct attgcagacc gggcccagat cttcctgaag
421 gcggcagaca tgctgagtgg gccgcgcagg gctgagatcc tcgccaagac catggtggga
481 cagggtaaga ccgtgatcca agcggagatt gacgctgcag cggaactcat cgacttcttc
541 cggttcaatg ccaagtatgc ggtggagctg gaggggcagc agcccatcag cgtgcccccg
601 agcaccaaca gcacggtgta ccggggtctg gagggcttcg tggcggccat ctcgcccttt
661 aacttcactg caatcggcgg caacctggcg ggggcaccgg ccctgatggg caacgtggtc
721 ctatggaagc ccagtgacac tgccatgctg gccagctatg ctgtctaccg catccttcgg
781 gaggctggcc tgccccccaa catcatccag tttgtgccag ctgatgggcc cctatttggg
841 gacactgtca ccagctcaga gcacctctgt ggcatcaact tcacaggcag tgtgcccacc
901 ttcaaacacc tgtggaagca ggtggcccag aacctggacc ggttccacac cttcccacgc
961 ctggctggag agtgcggcgg aaagaacttc cacttcgtgc accgctcggc cgacgtggag
1021 agcgtggtga gcgggaccct ccgctcagcc ttcgagtacg gtggccagaa gtgttccgcc
1081 tgctcgcgtc tctacgtgcc gcactcgctg tggccgcaga tcaaagggcg gctgctggag
1141 gagcacagtc ggatcaaagt gggcgaccct gcagaggatt ttgggacctt cttctctgca
1201 gtgattgatg ccaagtcctt tgcccgtatc aagaagtggc tggagcacgc gcgctcctcg
1261 cccagcctca ccatcctggc tgggggcaag tgtgatgact ccgtgggcta ctttgtggag
1321 ccctgcatcg tggagagcaa ggaccctcag gagcccatca tgaaggagga gatcttcggg
1381 cctgtactgt ctgtgtacgt ctacccggac gacaagtaca aggagacgct gcagctggtt
1441 gacagcacca ccagctatgg cctcacgggg gcagtgttct cccaggataa ggacgtcgtg
1501 caggaggcca caaaggtgct gaggaatgct gccggcaact tctacatcaa cgacaagtcc
1561 actggctcga tagtgggcca gcagcccttt gggggggccc gagcctctgg aaccaatgac
1621 aagccagggg gcccacacta catcctgcgc tggacgtcgc cgcaggtcat caaggagaca
1681 cataagcccc tgggggactg gagctacgcg tacatgcagt gagcccctct cgggctccac
1741 cgtccagctg tctgtccgtc cagatgcctc ctgcttggat tctgagtggt cagagatctg
1801 taaagcatga ctttcaagga tggttcttag gggactgtgt aaagtgttgg gtcttcctcc
1861 aggatgcctg catgggaccc cacccggagc tggtgtggcc attccccgaa gtgccactgg
1921 cccatggatg ggggtgggtg ctggtgcacc tgggctgggt gtgggttctg tgtccttcca
1981 ggatctgtgt catttcccat gaggggccgg ggcaggtggc tgggtggggg cacaggctgg
2041 agtattctta gttctactgg ttctacactg tgaggtggca atgggatttg ctcagatgcc
2101 acccaataaa atgcctgtta ctt
//