LOCUS HSU24266 3134 bp mRNA linear HUM 05-JUN-1996
DEFINITION Human pyrroline-5-carboxylate dehydrogenase (P5CDh) mRNA, long
form, complete cds.
ACCESSION U24266
VERSION U24266.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3134)
AUTHORS Hu,C.A., Lin,W.W. and Valle,D.
TITLE Cloning, characterization, and expression of cDNAs encoding human
delta 1-pyrroline-5-carboxylate dehydrogenase
JOURNAL J. Biol. Chem. 271 (16), 9795-9800 (1996)
PUBMED 8621661
REFERENCE 2 (bases 1 to 3134)
AUTHORS Hu,C.A., Lin,W. and Valle,D.L.
TITLE Direct Submission
JOURNAL Submitted (07-APR-1995) Chien-an A. Hu, Molecular Biology and
Genetics, Johns Hopkins University, PCTB802, 725 N. Wolfe St,
Baltimore, MD 21205, USA
FEATURES Location/Qualifiers
source 1..3134
/db_xref="H-InvDB:HIT000218742"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/tissue_type="kidney"
/note="P5CDhL; this is the long form of the mRNA which
contains a 1011-bp insert in the 3' untranslated region"
gene 1..3134
/gene="P5CDh"
CDS 31..1722
/gene="P5CDh"
/EC_number="1.5.1.12"
/function="P5C degradation"
/note="Method: conceptual translation supplied by author"
/codon_start=1
/product="pyrroline-5-carboxylate dehydrogenase"
/protein_id="AAC50500.1"
/translation="MLLPAPALRRALLSRPWTGAGLRWKHTSSLKVANEPVLAFTQGS
PERDALQKALKDLKGRMEAIPCVMGDEEVWTSDVQYQVSPFNHGHKVAKFCYADKSLL
NKAIEAALAARKEWDLKPIADRAQIFLKAADMLSGPRRAEILAKTMVGQGKTVIQAEI
DAAAELIDFFRFNAKYAVELEGQQPISVPPSTNSTVYRGLEGFVAAISPFNFTAIGGN
LAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADGPLFGDTVTSS
EHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGECGGKNFHFVHRSADVESVVS
GTLRSAFEYGGQKCSACSRLYVPHSLWPQIKGRLLEEHSRIKVGDPAEDFGTFFSAVI
DAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEPCIVESKDPQEPIMKEEIFG
PVLSVYVYPDDKYKETLQLVDSTTSYGLTGAVFSQDKDVVQEATKVLRNAAGNFYIND
KSTGSIVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPLGDWSYAYMQ"
polyA_site 3134
/gene="P5CDh"
/note="16 A nucleotides"
BASE COUNT 573 a 959 c 946 g 656 t
ORIGIN
1 tccagcgaac agccccgctt ctaacccgag atgctgctgc cggcgcccgc gctccgccgc
61 gccctgctgt cccgcccctg gaccggggcc ggcctgcggt ggaagcacac ctcctccctg
121 aaggtggcca acgagcccgt cttagccttc acgcagggca gccctgagcg agatgccctg
181 caaaaggcct tgaaggacct gaagggccgg atggaagcca tcccatgcgt gatgggggat
241 gaggaggtgt ggacgtcgga cgtgcagtac caagtgtcgc cttttaacca tggacataag
301 gtggccaagt tctgttatgc agacaagagc ctgctcaaca aagccattga ggctgccctg
361 gctgcccgga aagagtggga cctgaagcct attgcagacc gggcccagat cttcctgaag
421 gcggcagaca tgctgagtgg gccgcgcagg gctgagatcc tcgccaagac catggtggga
481 cagggtaaga ccgtgatcca agcggagatt gacgctgcag cggaactcat cgacttcttc
541 cggttcaatg ccaagtatgc ggtggagctg gaggggcagc agcccatcag cgtgcccccg
601 agcaccaaca gcacggtgta ccggggtctg gagggcttcg tggcggccat ctcgcccttt
661 aacttcactg caatcggcgg caacctggcg ggggcaccgg ccctgatggg caacgtggtc
721 ctatggaagc ccagtgacac tgccatgctg gccagctatg ctgtctaccg catccttcgg
781 gaggctggcc tgccccccaa catcatccag tttgtgccag ctgatgggcc cctatttggg
841 gacactgtca ccagctcaga gcacctctgt ggcatcaact tcacaggcag tgtgcccacc
901 ttcaaacacc tgtggaagca ggtggcccag aacctggacc ggttccacac cttcccacgc
961 ctggctggag agtgcggcgg aaagaacttc cacttcgtgc accgctcggc cgacgtggag
1021 agcgtggtga gcgggaccct ccgctcagcc ttcgagtacg gtggccagaa gtgttccgcc
1081 tgctcgcgtc tctacgtgcc gcactcgctg tggccgcaga tcaaagggcg gctgctggag
1141 gagcacagtc ggatcaaagt gggcgaccct gcagaggatt ttgggacctt cttctctgca
1201 gtgattgatg ccaagtcctt tgcccgtatc aagaagtggc tggagcacgc gcgctcctcg
1261 cccagcctca ccatcctggc tgggggcaag tgtgatgact ccgtgggcta ctttgtggag
1321 ccctgcatcg tggagagcaa ggaccctcag gagcccatca tgaaggagga gatcttcggg
1381 cctgtactgt ctgtgtacgt ctacccggac gacaagtaca aggagacgct gcagctggtt
1441 gacagcacca ccagctatgg cctcacgggg gcagtgttct cccaggataa ggacgtcgtg
1501 caggaggcca caaaggtgct gaggaatgct gccggcaact tctacatcaa cgacaagtcc
1561 actggctcga tagtgggcca gcagcccttt gggggggccc gagcctctgg aaccaatgac
1621 aagccagggg gcccacacta catcctgcgc tggacgtcgc cgcaggtcat caaggagaca
1681 cataagcccc tgggggactg gagctacgcg tacatgcagt gagcccctct cgggctccac
1741 cgtccagctg tctgtccgtc caggtggccg acctcactgc acagacccca ctccagcccc
1801 tccacccctt cttcatgcac agctgccttt ctataatccg ggcttgactc ccttcttacc
1861 actgtattct ggcctctccc atgcctcagg ctctggtttg agatcgtgct ggggaggaac
1921 atggccacta ccccttatcc catcggccat gtgggaggta tgaccctggt gcctggcagg
1981 ttctccctct gccctccact gggcccagtg gctcagggac ctggggaaag gagatggagc
2041 agctcttggg atcctttggg gaaaaggagg ccattctggg ccccttggca aacctcacca
2101 ctcacagagg ctcctggcct tgatccctgc ccctccaggt gtccagggta aagtgtaact
2161 cagactgacc tgtggggcac agggggcacc agctggcctt gccctctctg gtctgggctg
2221 tctaccttcc tcactgtatc tttgcccaga cccacctggg ccagtaggcc tgtccccagc
2281 cacacacctt agatgctggc atgccttact ccaggtgcct gtgtttggcc gaggcctgtg
2341 tgattcccgg tctgcaccac atggcggggt tggggggccg ctggaggcca cctgccaagg
2401 cgtgggatgg gatggtcctg ccggtttagg ccgtgattct ggaaaacctt ggatgggcct
2461 tcgtcctatg tcagccttcc ctttgatcct caggccctac ctgtagagac ctccactcct
2521 agagccagtc tcagggtctg ggatttccct gcaggagctc agccaccact gtgccatggt
2581 gacacaggcc aaggcagaca ttggccctcc cttctcccag cccccagagg cctggccttg
2641 ggttcgtcag catgggccga ggacgttgcc tgtagaatcc tcctctgcct gggagtggct
2701 ctgtgtggac cagtccctca ctggcccatt ctttttttga cgcagccaat ctgtgaccac
2761 gattcctccc acagatgcct cctgcttgga ttctgagtgg tcagagatct gtaaagcatg
2821 actttcaagg atggttctta ggggactgtg taaagtgttg ggtcttcctc caggatgcct
2881 gcatgggacc ccacccggag ctggtgtggc cattccccga agtgccactg gcccatggat
2941 gggggtgggt gctggtgcac ctgggctggg tgtgggttct gtgtccttcc aggatctgtg
3001 tcatttccca tgaggggccg gggcaggtgg ctgggtgggg gcacaggctg gagtattctt
3061 agttctactg gttctacact gtgaggtggc aatgggattt gctcagatgc cacccaataa
3121 aatgcctgtt actt
//