LOCUS HSU23765 1949 bp mRNA linear HUM 29-MAR-1996
DEFINITION Human Bak protein mRNA, complete cds.
ACCESSION U23765
VERSION U23765.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1949)
AUTHORS Chittenden,T., Harrington,E.A., O'Connor,R., Flemington,C.,
Lutz,R.J., Evan,G.I. and Guild,B.C.
TITLE Induction of apoptosis by the Bcl-2 homologue Bak
JOURNAL Nature 374 (6524), 733-736 (1995)
PUBMED 7715730
REFERENCE 2 (bases 1 to 1949)
AUTHORS Chittenden,T.
TITLE Direct Submission
JOURNAL Submitted (30-MAR-1995) Thomas Chittenden, Apoptosis Technology
Inc., 148 Sidney St., Cambridge, MA 02139, USA
FEATURES Location/Qualifiers
source 1..1949
/db_xref="H-InvDB:HIT000218704"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="Jurkat cell"
/clone_lib="Jurkat cell cDNA library (Stratagene)"
CDS 65..700
/function="induction of apoptosis"
/codon_start=1
/product="Bak protein"
/protein_id="AAA93066.1"
/translation="MASGQGPGPPRQECGEPALPSASEEQVAQDTEEVFRSYVFYRHQ
QEQEAEGVAAPADPEMVTLPLQPSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQP
TAENAYEYFTKIATSLFESGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVD
FMLHHCIARWIAQRGGWVAALNLGNGPILNVLVVLGVVLLGQFVVRRFFKS"
polyA_site 1949
BASE COUNT 368 a 557 c 575 g 449 t
ORIGIN
1 tgagccaccc gggttgggcc aggatcccgg caggctgatc ccgtcctcca ctgagacctg
61 aaaaatggct tcggggcaag gcccaggtcc tcccaggcag gagtgcggag agcctgccct
121 gccctctgct tctgaggagc aggtagccca ggacacagag gaggttttcc gcagctacgt
181 tttttaccgc catcagcagg aacaggaggc tgaaggggtg gctgcccctg ccgacccaga
241 gatggtcacc ttacctctgc aacctagcag caccatgggg caggtgggac ggcagctcgc
301 catcatcggg gacgacatca accgacgcta tgactcagag ttccagacca tgttgcagca
361 cctgcagccc acggcagaga atgcctatga gtacttcacc aagattgcca ccagcctgtt
421 tgagagtggc atcaattggg gccgtgtggt ggctcttctg ggcttcggct accgtctggc
481 cctacacgtc taccagcatg gcctgactgg cttcctaggc caggtgaccc gcttcgtggt
541 cgacttcatg ctgcatcact gcattgcccg gtggattgca cagaggggtg gctgggtggc
601 agccctgaac ttgggcaatg gtcccatcct gaacgtgctg gtggttctgg gtgtggttct
661 gttgggccag tttgtggtac gaagattctt caaatcatga ctcccaaggg tgccctttgg
721 gtcccggttc agacccctgc ctggacttaa gcgaagtctt tgccttctct gttcccttgc
781 aggggtcccc cctcaagagt acagaagctt tagcaagtgt gcactccagc ttcggagggc
841 ccctgcgtgg gggccagtca ggctgcagag gcacctcaac attgcatggt gctagtgggc
901 cctctctctg ggcccagggg ctgtggccgt ctcctccctc agctctctgg gacctcctta
961 gccctgtctg ctaggcgctg gggagactga taacttgggg aggcaagaga ctgggagcca
1021 cttctcccca gaaagtgttt aacggtttta gctttttata atacccttgt gagagcccat
1081 tcccaccatt ctacctgagg ccaggacgtc tggggtgtgg ggattggtgg gtctatgttc
1141 cccaggattc agctattctg gaagatcagc accctaagag atgggactag gacctgagcc
1201 tggtcctggc cgtccctaag catgtgtccc aggagcagga cctactagga gaggggggcc
1261 aaggtcctgc tcaactctac ccctgctccc attcctccct ccggccatac tgcctttgca
1321 gttggactct cagggattct gggcttgggg tgtggggtgg ggtggagtcg cagaccagag
1381 ctgtctgaac tcacgtgtca gaagcctcca agcctgcctc ccaaggtcct ctcagttctc
1441 tcccttcctc tctccttata gacacttgct cccaacccat tcactacagg tgaaggctct
1501 caccccatcc ctgggggcct tgggtgagtg gcctgctaag gctcctcctt gcccagacta
1561 cagggcttag gacttggttt gttatatcag ggaaaaggag tagggagttc atctggaggg
1621 ttctaagtgg gagaaggact atcaacacca ctaggaatcc cagaggtggg atcctccctc
1681 atggctctgg cacagtgtaa tccaggggtg tagatggggg aactgtgaat acttgaactc
1741 tgttccccca ccctccatgc tcctcacctg tctaggtctc ctcagggtgg ggggtgacag
1801 tgccttctct attgggcaca gcctagggtc ttgggggtca ggggggagaa gttcttgatt
1861 cagccaaatg cagggagggg aggcagatgg agcccatagg ccacccccta tcctctgagt
1921 gtttggaaat aaactgtgca atcccctca
//