LOCUS HSU23070 1521 bp mRNA linear HUM 11-APR-1996
DEFINITION Human putative transmembrane protein (nma) mRNA, complete cds.
ACCESSION U23070
VERSION U23070.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1521)
AUTHORS Degen,W.G., Weterman,M.A., van Groningen,J.J., Cornelissen,I.M.,
Lemmers,J.P., Agterbos,M.A., Geurts van Kessel,A., Swart,G.W. and
Bloemers,H.P.
TITLE Expression of nma, a novel gene, inversely correlates with the
metastatic potential of human melanoma cell lines and xenografts
JOURNAL Int. J. Cancer 65 (4), 460-465 (1996)
PUBMED 8621228
REFERENCE 2 (bases 1 to 1521)
AUTHORS Degen,W.G.J.
TITLE Direct Submission
JOURNAL Submitted (20-MAR-1995) Winfried G.J. Degen, Dept. of Biochemistry,
University of Nijmegen, P.O. Box 9101, Nijmegen, 6500 HB, The
Netherlands
FEATURES Location/Qualifiers
source 1..1521
/db_xref="H-InvDB:HIT000218697"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="MV1"
gene 1..1521
/gene="nma"
CDS 373..1155
/gene="nma"
/experiment="experimental evidence, no additional details
recorded"
/note="expression in poorly metastatic human melanoma cell
lines; no expression in highly metastatic human melanoma
cell lines; similar to EST encoded by GenBank Accession
Number T73919; putative transmembrane protein"
/codon_start=1
/protein_id="AAC50435.1"
/translation="MDRHSSYIFIWLQLELCAMAVLLTKGEIRCYCDAAHCVATGYMC
KSELSACFSRLLDPQNSNSPLTHGCLDSLASTTDICQAKQARNHSGTTIPTLECCHED
MCNYRGLHDVLSPPRGEASGQGNRYQHDGSRNLITKVQELTSSKELWFRAAVIAVPIA
GGLILVLLIMLALRMLRSENKRLQDQRQQMLSRLHYSFHGHHSKKGQVAKLDLECMVP
VSGHENCCLTCDKMRQADLSNDKILSLVHWGMYSGHGKLEFV"
BASE COUNT 364 a 395 c 414 g 348 t
ORIGIN
1 ctggcgcggg cgggagctgc ggcggatacc cttgcgtgct gtggagaccc tactctcttc
61 gctgagaacg gccgctagcg gggactgaag gccgggagcc cactcccgac ccggggctag
121 cgtgcgtccc tagagtcgag cggggcaagg gagccagtgg ccgccgacgg gggaccggga
181 aacttttctg ggctcctgga gagccctgta gccgcgctcc atgctccggc agcggcccga
241 aacccagccc cgccgctgac ggagcccgcc gctccgggca gggcccatgc cctgcgcgct
301 ccgggggtcg tagctgccgc cgagccgggg ctccggaagc cggcgggggc gccgcggccg
361 tgcggggcgt caatggatcg ccactccagc tacatcttca tctggctgca gctggagctc
421 tgcgccatgg ccgtgctgct caccaaaggt gaaattcgat gctactgtga tgctgcccac
481 tgtgtagcca ctggttatat gtgtaaatct gagctcagcg cctgcttctc tagacttctt
541 gatcctcaga actcaaattc cccactcacc catggctgcc tggactctct tgcaagcacg
601 acagacatct gccaagccaa acaggcccga aaccactctg gcaccaccat acccacattg
661 gaatgctgtc atgaagacat gtgcaattac agagggctgc acgatgttct ctctcctccc
721 aggggtgagg cctcaggaca aggaaacagg tatcagcatg atggtagcag aaaccttatc
781 accaaggtgc aggagctgac ttcttccaaa gagttgtggt tccgggcagc ggtcattgcc
841 gtgcccattg ctggagggct gattttagtg ttgcttatta tgttggccct gaggatgctt
901 cgaagtgaaa ataagaggct gcaggatcag cggcaacaga tgctctcccg tttgcactac
961 agctttcacg gacaccattc caaaaagggg caggttgcaa agttagactt ggaatgcatg
1021 gtgccggtca gtgggcacga gaactgctgt ctgacctgtg ataaaatgag acaagcagac
1081 ctcagcaacg ataagatcct ctcgcttgtt cactggggca tgtacagtgg gcacgggaag
1141 ctggaattcg tatgacggag tcttatctga actacactta ctgaacagct tgaaggcctt
1201 ttgagttctg ctggacagga gcactttatc tgaagacaaa ctcatttaat catctttgag
1261 agacaaaatg acctctgcaa acagaatctt ggatatttct tctgaaggat tatttgcaca
1321 gacttaaata cagttaaatg tgttatttgc ttttaaaatt ataaaaagca aagagaagac
1381 tttgtacaca ctgtcaccag ggttatttgc atccaaggga gctggaattg agtacctaaa
1441 taaacaaaaa tgtgccctat gtaagcttct acatcttgat ttattgtaaa gatttaaaag
1501 aaatatatat attttgtctg a
//