LOCUS HSU23028 2291 bp mRNA linear HUM 22-AUG-1996
DEFINITION Human eukaryotic initiation factor 2B-epsilon mRNA, partial cds.
ACCESSION U23028
VERSION U23028.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2291)
AUTHORS Asuru,A.I., Mellor,H., Thomas,N.S., Yu,L., Chen,J.J., Crosby,J.S.,
Hartson,S.D., Kimball,S.R., Jefferson,L.S. and Matts,R.L.
TITLE Cloning and characterization of cDNAs encoding the epsilon-subunit
of eukaryotic initiation factor-2B from rabbit and human
JOURNAL Biochim. Biophys. Acta 1307 (3), 309-317 (1996)
PUBMED 8688466
REFERENCE 2 (bases 1 to 2291)
AUTHORS Asuru,A.I., Mellor,H., Thomas,N.S.B., Yu,L., Chen,J.-J.,
Crosby,J.S., Hartson,S.D., Kimball,S.R., Jefferson,L.S. and
Matts,R.L.
TITLE Direct Submission
JOURNAL Submitted (17-MAR-1995) Robert L. Matts, Biochemistry & Molecular
Biology, Oklahoma State University, 246 NRC, Stillwater, OK
74078-0454, USA
FEATURES Location/Qualifiers
source 1..2291
/db_xref="H-InvDB:HIT000218696"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="U-937 histiocytic lymphoma"
CDS <1..1926
/note="epsilon subunit of eukaryotic initiation factor 2B"
/codon_start=1
/product="eIF-2Bepsilon"
/protein_id="AAC50646.1"
/translation="EFLTATGVQETFVFCCWKAAQIKEHLLKSKWCRPTSLNVVRIIT
SELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINITRALEEHRLRRKLEKNVSVMT
MIFKESSPSHPTRCHEDNVVVAVDSTTNRVLHFQKTQGLRRFAFPLSLFQGSSDGVEV
RYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGLLVNEEILGNQIHMHVTAKEYGA
RVSNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQSCTHSRHNIYRGPEVSLGHGSIL
EENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIHQSLLC
DNAEVKERVTLKPRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGEFSDDSGAD
QEKDKVKMKGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNLWGLKINMEEESESESE
QSMDSEEPDSRGGSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNVS
LKEVMQVLSHVVLEFPLQQMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEAL
AAIEDFFLEHEALGISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQLRKNQQLQ
RFIQWLKEAEEESSEDD"
polyA_site 2291
/note="21 A nucleotides"
BASE COUNT 588 a 540 c 630 g 533 t
ORIGIN
1 gaattcctga ctgccacagg tgtacaggaa acatttgtct tttgttgctg gaaagctgct
61 caaatcaaag aacatttact gaagtcaaag tggtgccgcc ctacatctct caatgtggtt
121 cgaataatta catcagagct ctatcgatca ctgggagatg tcctccgtga tgttgatgcc
181 aaggctttgg tgcgctctga ctttcttctg gtgtatgggg atgtcatctc aaacatcaat
241 atcaccagag cccttgagga acacaggttg agacggaagc tagaaaaaaa tgtttctgtg
301 atgacgatga tcttcaagga gtcatccccc agccacccaa ctcgttgcca cgaagacaat
361 gtggtagtgg ctgtggatag taccacaaac agggttctcc attttcagaa gacccagggt
421 ctccggcgtt ttgcatttcc tctgagcctg tttcagggca gtagtgatgg agtggaggtt
481 cgatatgatt tactggattg tcatatcagc atctgttctc ctcaggtggc acaactcttt
541 acagacaact ttgactacca aactcgagat gactttgtgc gaggtctctt agtgaatgag
601 gagatcctag ggaaccagat ccacatgcac gtaacagcta aggaatatgg tgcccgtgtc
661 tccaacctac acatgtactc agctgtctgt gctgacgtca tccgccgatg ggtctaccct
721 ctcaccccag aggcgaactt cactgacagc accacccaga gctgcactca ttcccggcac
781 aacatctacc gagggcctga ggtcagcctg ggccatggca gcatcctaga ggaaaatgtg
841 ctcctgggct ctggcactgt cattggcagc aattgcttta tcaccaacag tgtcattggc
901 cccggctgcc acattggtga taacgtggtg ctggaccaga cctacctgtg gcagggtgtt
961 cgagtggcgg ctggagcaca gatccatcag tctctgcttt gtgacaatgc tgaggtcaag
1021 gaacgagtga cactgaaacc acgctctgtc ctcacttccc aggtggtcgt gggcccaaat
1081 atcacgctgc ctgagggctc ggtgatctct ttgcaccctc cagatgcaga ggaagatgaa
1141 gatgatggcg agttcagtga tgattctggg gctgaccaag aaaaggacaa agtgaagatg
1201 aaaggttaca atccagcaga agtaggagct gctggcaagg gctacctctg gaaagctgca
1261 ggcatgaaca tggaggaaga ggaggaactg cagcagaatc tgtggggact caagatcaac
1321 atggaagaag agagtgaaag tgaaagtgag caaagtatgg attctgagga gccggacagc
1381 cggggaggct cccctcagat ggatgacatc aaagtgttcc agaatgaagt tttaggaaca
1441 ctacagcggg gcaaagagga gaacatttct tgtgacaatc tcgtcctgga aatcaactct
1501 ctcaagtatg cctataacgt aagtctaaag gaggtgatgc aggtactgag ccacgtggtc
1561 ctggagttcc ccctgcaaca gatggattcc ccgcttgact caagccgcta ctgtgccctg
1621 ctgcttcctc tgctaaaggc ctggagccct gtttttagga actacataaa gcgcgcagcc
1681 gaccatttgg aagcgttagc agccattgag gacttcttcc tagagcatga agctcttggt
1741 atttccatgg ccaaggtact gatggctttc taccagctgg agatcctggc tgaggaaaca
1801 attctgagct ggttcagcca aagagataca actgacaagg gccagcagtt gcgcaagaat
1861 caacagctgc agaggttcat ccagtggcta aaagaggcag aagaggagtc atctgaagat
1921 gactgaagtc acactgcctg ctcctttggg tgtgattgag tgccctcctg gctcctgggc
1981 tgggacaagt gaggaactag ctgcagaggg atgagtgacc accatccagg ctgagactga
2041 aaggagcaga ggctggaact acagtattct ttcccctgct agcaaccatg tgcctcccat
2101 cctgactgtg gagttgggat gtggaagtgg ggctggaaca aagcttctgc ctagggagga
2161 gctaagcagg cccggcagtt ggaggaaggc cagaggaaca gctttgtgct ccggctttcc
2221 ctcagggaac agcagagagc agttggctct ttctgctgct tgtatatgtt aatattaaaa
2281 gagagtggtg t
//