LOCUS HSU22233 2269 bp mRNA linear HUM 25-NOV-1995
DEFINITION Human methylthioadenosine phosphorylase (MTAP) mRNA, complete cds.
ACCESSION U22233
VERSION U22233.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2269)
AUTHORS Olopade,O.I., Pomykala,H.M., Hagos,F., Sveen,L.W., Espinosa,R. III,
Dreyling,M.H., Gursky,S., Stadler,W.M., Le Beau,M.M. and
Bohlander,S.K.
TITLE Construction of a 2.8-megabase yeast artificial chromosome contig
and cloning of the human methylthioadenosine phosphorylase gene
from the tumor suppressor region on 9p21
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 92 (14), 6489-6493 (1995)
PUBMED 7604019
REFERENCE 2 (bases 1 to 2269)
AUTHORS Olopade,O.I.
TITLE Direct Submission
JOURNAL Submitted (06-MAR-1995) Olufunmilayo I. Olopade, Medicine,
University of Chicago Pritzker School of Medicine, 5841 S. Maryland
Avenue, Chicago, IL 60637-1470, USA
FEATURES Location/Qualifiers
source 1..2269
/db_xref="H-InvDB:HIT000218674"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="9"
/map="9p21"
/clone="18-11 cDNA"
/sex="male"
/cell_line="primary culture"
/cell_type="fibroblast"
/tissue_type="epidermis"
gene 1..2269
/gene="MTAP"
CDS 122..973
/gene="MTAP"
/codon_start=1
/product="methylthioadenosine phosphorylase"
/protein_id="AAA81646.1"
/translation="MASGTTTTAVKIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDA
LILGKIKNVDCILLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEI
QPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLG
LRCHSKGTMVTIEGPRFSSRAESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMA
TDYDCWKEHEEAVSVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLHNLKNMAQF
SVLLPRH"
BASE COUNT 725 a 407 c 490 g 647 t
ORIGIN
1 gaattccgct ccgcactgct cactcccgcg cagtgaggtt ggcacagcca ccgctctgtg
61 gctcgcttgg ttcccttagt cccgagcgct cgcccactgc agattccttt cccgtgcaga
121 catggcctct ggcaccacca ccaccgccgt gaagattgga ataattggtg gaacaggcct
181 ggatgatcca gaaattttag aaggaagaac tgaaaaatat gtggatactc catttggcaa
241 gccatctgat gccttaattt tggggaagat aaaaaatgtt gattgcatcc tccttgcaag
301 gcatggaagg cagcacacca tcatgccttc aaaggtcaac taccaggcga acatctgggc
361 tttgaaggaa gagggctgta cacatgtcat agtgaccaca gcttgtggct ccttgaggga
421 ggagattcag cccggcgata ttgtcattat tgatcagttc attgacagga ccactatgag
481 acctcagtcc ttctatgatg gaagtcattc ttgtgccaga ggagtgtgcc atattccaat
541 ggctgagccg ttttgcccca aaacgagaga ggttcttata gagactgcta agaagctagg
601 actccggtgc cactcaaagg ggacaatggt cacaatcgag ggacctcgtt ttagctcccg
661 ggcagaaagc ttcatgttcc gcacctgggg ggcggatgtt atcaacatga ccacagttcc
721 agaggtggtt cttgctaagg aggctggaat ttgttacgca agtatcgcca tggcgacaga
781 ttatgactgc tggaaggagc acgaggaagc agtttcggtg gaccgggtct taaagaccct
841 gaaagaaaac gctaataaag ccaaaagctt actgctcact accatacctc agatagggtc
901 cacagaatgg tcagaaaccc tccataacct gaagaatatg gcccagtttt ctgttttatt
961 accaagacat taaagtagca tggctgccca ggagaaaaga agacattcta attccagtca
1021 ttttgggaat tcctgcttaa cttgaaaaaa atatgggaaa gacatgcagc tttcatgccc
1081 ttgcctatca aagagtatgt tgtaagaaag acaagacatt gtgtgtatta gagactcctg
1141 aatgatttag acaacttcaa aatacagaag aaaagcaaat gactagtaaa catgtgggaa
1201 aaaatattac attttaaggg ggaaaaaaaa aaccccacca ttctcttctc cccctattaa
1261 atttgcaaca ataaagggtg gagggtaatc tctactttcc tatactgcca aagaatgtga
1321 ggaagaaatg ggactctttg gttatttatt gatgcgactg taaattggta cagtatttct
1381 ggagggcaat ttggtaaaat gcatcaaaag acttaaaaat acggacgtcc tttggtgctg
1441 ggaactctac atctagcaat ttctctttaa aaccatatca gagatgcata caaagaatta
1501 tatataaaga agggtgttta ataatgatag ttataataat aaataattga aacaatctga
1561 atcccttgca attggaggta aattatgtct tagttataat ctagattgtg aatcagccaa
1621 ctgaaaatcc tttttgcata tttcaatgtc ctaaaaagac acggttgctc tatatatgaa
1681 gtgaaaaaag gatatggtag cattttatag tactagtttt gctttaaaat gctatgtaaa
1741 tatacaaaaa aactagaaag aaatatatat aaccttgtta ttgtatttgg gggagggata
1801 ctgggataat ttttattttc tttgaatctt tctgtgtctt cacatttttc tacagtgaat
1861 ataatcaaat agtaaagggc cgtaaaaata aaagtggatt tagaaagatc cagttcttga
1921 aaacactgtt tctggtaatg aagcagaatt taagttggta atattaaggt gaatgtcatt
1981 taagggagtt acatctttat tctgctaaag aagaggatca ttgatttctg tacagtcaga
2041 acagtacttg ggtgtgcaac agctttctga gaaaagctag gtgtataata gtttaactga
2101 aagtttaact atttaaaaga ctaaatgcac attttatggt atctgatatt ttaaaaagta
2161 atgtgagctt ctccttttta tgagttaaat tattttatac gagttggtaa tttgtgcctt
2221 ttaataaagt ggaagcttgc tttttaaaaa aaaaaaaaaa gcggaattc
//