LOCUS HSU20489 5415 bp mRNA linear HUM 05-DEC-1995
DEFINITION Human glomerular epithelial protein 1 (GLEPP1) mRNA, complete cds.
ACCESSION U20489
VERSION U20489.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5415)
AUTHORS Wiggins,R.C., Wiggins,J.E., Goyal,M., Wharram,B.L. and Thomas,P.E.
TITLE Molecular cloning of cDNAs encoding human GLEPP1, a membrane
protein tyrosine phosphatase: characterization of the GLEPP1
protein distribution in human kidney and assignment of the GLEPP1
gene to human chromosome 12p12-p13
JOURNAL Genomics 27 (1), 174-181 (1995)
PUBMED 7665166
REFERENCE 2 (bases 1 to 5415)
AUTHORS Wharram,B.L.
TITLE Direct Submission
JOURNAL Submitted (30-JAN-1995) Bryan L. Wharram, Nephrology Division,
Internal Medicine, University of Michigan Medical School, 1150 W.
Medical Center Dr., Rm. 1562 MSRBII, Ann Arbor, MI 48109-0676, USA
FEATURES Location/Qualifiers
source 1..5415
/db_xref="H-InvDB:HIT000218558"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="12"
/map="12p12-13"
/tissue_type="kidney, cortex"
/dev_stage="adult"
gene 1..5415
/gene="GLEPP1"
CDS 173..3739
/gene="GLEPP1"
/note="membrane protein tyrosine phosphatase"
/codon_start=1
/product="glomerular epithelial protein 1"
/protein_id="AAA82892.1"
/translation="MGHLPTGIHGARRLLPLLWLFVLFKNATAFHVTVQDDNNIVVSL
EASDVISPASVYVVKITGESKNYFFEFEEFNSTLPPPVIFKASYHGLYYIITLVVVNG
NVVTKPSRSITVLTKPLPVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEG
KDFRTMLYKDFFKGKTVFNHWLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQH
RTAPYPPQNISVRIVNLNKNNWEEQSGNFPEESFMRSQDTIGKEKLFHFTEETPEIPS
GNISSGWPDFNSSDYETTSQPYWWDSASAAPESEDEFVSVLPMEYENNSTLSETEKST
SGSFSFFPVQMILTWLPPKPPTAFDGFHIHIEREENFTEYLMVDEEAHEFVAELKEPG
KYKLSVTTFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTEKPQHVSVHVLSSTTAL
MSWTSSQENYNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPIIENLVPGAQYQVV
IYLRKGPLIGPPSDPVTFAIVPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMF
YFNPATMTSEWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSS
TISFITAPVAPEITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV
TRNVMTAILSLPPGDIYNLSVTACTERGSNTSMLRLVKLEPAPPKSLFAVNKTQTSVT
LLWVEEGVADFFEVFCQQVGSSQKTKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSH
DSPSVPTFIAVSTMVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECG
AGTFVNFASLERDGKLPYNWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQF
EELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPG
YNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPI
AYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQ
FVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSY
RMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS"
sig_peptide 173..259
/gene="GLEPP1"
mat_peptide 260..3736
/gene="GLEPP1"
/product="glomerular epithelial protein 1"
/note="membrane protein tyrosine phosphatase"
BASE COUNT 1539 a 1214 c 1166 g 1496 t
ORIGIN
1 gggcgcagag gaggaaaggg agcaggcgca gggggactgg aaaggcagca tgcgctcgcc
61 aggagcaacc tcggcgccca gggtctgagg ctgcagccca gttcgccatt gtgagccgcc
121 gccgggggag tccgctagcg cacgcgtgcc cccgagtccc cgtccgcgca cgatggggca
181 cctgcccacg gggatacacg gcgcccgccg cctcctgcct ctgctctggc tctttgtgct
241 gttcaagaat gctacagctt tccatgtaac tgtccaagat gataataaca tcgttgtctc
301 attagaagct tcagacgtca tcagtccagc atctgtgtat gttgtgaaga taactggtga
361 atccaaaaat tatttcttcg aatttgagga attcaacagc actttgcctc ctcctgttat
421 tttcaaggcc agttatcatg gcctttatta tataatcact ctggtagtgg taaatggaaa
481 tgtggtgacc aagccatcca gatcaatcac tgtgttaaca aaacctctac ctgtaaccag
541 tgtttccata tatgactata aaccttctcc tgaaacagga gtcctgtttg aaatacatta
601 tccagaaaaa tataacgttt tcacaagagt gaacattagc tactgggaag gtaaagactt
661 ccggacaatg ctatataaag atttctttaa gggaaaaaca gtatttaatc actggctgcc
721 aggaatgtgt tatagtaata tcacctttca gctggtatct gaggcaactt ttaataaaag
781 tacccttgtt gagtacagtg gtgtcagtca cgaacccaaa cagcacagaa ctgcccctta
841 tccacctcaa aatatttccg ttcgtatcgt aaacttgaac aaaaacaact gggaagaaca
901 gagtggcaat ttcccagaag aatccttcat gagatcacaa gatacaatag gaaaagaaaa
961 actcttccat tttacagaag aaacccctga aattccctcg ggcaacattt cttccggttg
1021 gcctgatttt aatagcagtg actatgaaac tacgtctcag ccatattggt gggacagtgc
1081 atctgcagct cctgaaagtg aagatgaatt tgtcagcgta cttcccatgg aatacgaaaa
1141 taacagtaca ctcagtgaga cagagaagtc aacatcaggc tctttctcct ttttccctgt
1201 gcaaatgata ttgacctggt taccacccaa accacccact gcttttgatg ggttccatat
1261 ccatattgaa cgagaagaga actttactga atatttgatg gtggatgaag aagcacatga
1321 atttgttgca gaactgaagg aacctgggaa atataagtta tctgtgacaa cctttagttc
1381 ctcaggatct tgtgaaactc gaaaaagtca gtcagcaaaa tcactcagct tttatatcag
1441 tccttcagga gagtggattg aagaactgac cgagaagccg cagcacgtga gtgtccacgt
1501 tttaagctca accactgcct tgatgtcctg gacatcttcc caagagaact acaacagcac
1561 cattgtgtct gtggtgtcgc tgacctgcca gaaacaaaag gagagccaga ggcttgaaaa
1621 gcagtactgc actcaggtga actcaagcaa acctattatt gaaaatctgg ttcctggtgc
1681 ccagtaccag gttgtaatat acctaaggaa aggccctttg attggaccac cttcagatcc
1741 tgtgacattt gctattgttc ccacaggaat aaaggattta atgctctatc ctttgggtcc
1801 tacggccgtg gttctgagct ggaccagacc ttatttaggc gtgttcagaa aatacgtggt
1861 tgaaatgttt tatttcaacc ctgctacaat gacatcagag tggaccacct actatgaaat
1921 agcagcaact gtttccttaa ctgcatccgt gagaatagct aatctgctgc cagcatggta
1981 ctacaacttc cgggttacca tggtgacgtg gggagatcca gaattgagct gctgtgacag
2041 ctctaccatc agcttcataa cagccccagt ggctccggaa atcacttctg tggaatattt
2101 caacagtctg ttatatatca gttggacata tggggatgat acaacggact tgtcccattc
2161 tagaatgctt cactggatgg tggttgcaga aggaaaaaag aaaattaaaa agagtgtaac
2221 acgcaatgtc atgactgcaa ttctcagctt gcctccaggc gacatctata acctctcagt
2281 aactgcttgt actgaaagag gaagtaatac ctccatgctc cgccttgtca agctagaacc
2341 agctccaccc aaatcactct tcgcagtgaa caaaacccag acttcagtga ctttgctgtg
2401 ggtggaagag ggagtagctg atttctttga agttttctgt caacaagttg gctccagtca
2461 gaaaaccaaa cttcaggaac cagttgctgt ttcttcccat gtcgtgacca tctccagcct
2521 tcttcctgcc actgcctaca attgtagtgt caccagcttt agccatgaca gccccagtgt
2581 ccctacgttc atagccgtct caacaatggt tacagagatg aatcccaatg tggtagtgat
2641 ctccgtgctg gccatcctta gcacactttt aattggactg ttgcttgtta ccctcattat
2701 tcttaggaaa aagcatctgc agatggctag ggagtgtgga gctggtacat ttgtcaattt
2761 tgcatcctta gagagggatg gaaagcttcc atacaactgg agtaaaaatg gtttaaagaa
2821 gaggaaactg acaaacccgg ttcaactgga tgactttgat gcctatatta aggatatggc
2881 caaagactct gactataaat tttctcttca gtttgaggag ttgaaattga ttggactgga
2941 tatcccacac tttgctgcag atcttccact gaatcgatgt aaaaaccgtt acacaaacat
3001 cctaccatat gacttcagcc gtgtgagatt agtctccatg aatgaagagg aaggtgcaga
3061 ctacatcaat gccaactata ttcctggata caactcaccc caggagtata ttgccaccca
3121 ggggccactg cctgaaacca gaaatgactt ctggaagatg gtcctgcaac aaaagtctca
3181 gattattgtc atgctcactc agtgtaatga gaaaaggagg gtgaaatgtg accattactg
3241 gccattcacg gaagaaccta tagcctatgg agacatcact gtggagatga tttcagagga
3301 agagcaggac gactgggcct gtagacactt ccggatcaac tatgctgacg agatgcagga
3361 tgtgatgcat tttaactaca ctgcatggcc tgatcatggt gtgcccacag caaatgctgc
3421 agaaagtatc ctgcagtttg tacacatggt ccgacagcaa gctaccaaga gcaaaggtcc
3481 catgatcatt cactgcagtg ctggcgtggg acggacagga acattcattg ccctggacag
3541 gctcttgcag cacattcggg atcatgagtt tgttgacatc ttagggctgg tgtcagaaat
3601 gaggtcatac cggatgtcta tggtacagac agaggagcag tacattttta tccatcagtg
3661 tgtgcaactg atgtggatga agaagaagca gcagttctgc atcagtgatg tcatatacga
3721 gaatgttagc aagtcctagt tcagaatccg gagcagagag gacatgatgt gcgcccatcc
3781 tcccttgctt ccagattgtt ttagtgggcc ctgatggtca tttttctaaa cagaggccct
3841 gctttgtaat atgtggccaa ggagataatt tatctcacag aagcaccggg aagacttagc
3901 cttaaagagc ctacagtgtc cttttggact ctttcacttc gggacattta ataatggacc
3961 aaattcaaca gaacaccagg aaggtcaaga cgctctccaa agggcaggaa gtacagcact
4021 tccgaagagt ttagttggcc ctttgctggt tgggctgagt tttttatttt taagtgtttg
4081 tttttcagtg caataatttt tgtgtgtgtg tgattcttat cagaaagttg aattgttttc
4141 tgcctacacc gttcatcagc cccataaccc aggaaggaac aggcattgtt agcatcagat
4201 tatacctcat tattaaaagg aggcatggcc acacatgaag aaatggtcat tctacttcaa
4261 agaaattgag ccagcactat ctgtactcca acattaccgg atctggattg gggaggttgg
4321 tcagggaaga gaggggttct acccacagat caactgtgta atcttttact attcaagcta
4381 taattcagct tcaaagtaga gtagaaaaaa aattgtctta actgttctag ttcttgatgg
4441 ttttcttcct tattaacagt tggtgtttct tccttggccc ttttggacta atgttactgt
4501 ccaagttctt tctcaagaaa ccacatctgg ttcagaagag tgtcaagttg gactctttga
4561 actctgttgc tgtctgagca atcgtggtgc ctagactttg cattccttgt tctgttgacc
4621 tgcatacatg tgagagctat ttctttaaga actatatagg ctgtgaaaac gcactttctt
4681 tcccccaaag agctgggaat ttatgaagtt atggcaatga actgcagcat gctgggacaa
4741 ttatttgact actttttttt gtaatattgt caaatgtctc tatggattct gacagagatt
4801 tctttttgtt ttgttattct tttggttgtc agtttcattt taacgagtgt aactagtaac
4861 attttattct ttggattttg tataattaca gtacatgatt gtgtattgtg acatgaatgc
4921 tgtcaaaatg acattgatgg cattgtgaag cctgttactt tgtgtcactt cctgataaat
4981 aagaggtgat gacatggata tacaacagaa aacactttga gttgaaagta aacacaagct
5041 ggctgcttcc ctgtggcaaa aaaaaaaaaa atagcattcc tgcacatctg tacccacgcc
5101 ttcttcaaag ccatactatt tatgtgctcc ggatccatca tccacaacct taacaatgaa
5161 caagatattc gaaaaatagg aggactactc aaaaccatac ctctcacttc aacctccctc
5221 accattggca gcctagcatt agcaggaata cctttcctca caggtttcta ctccaaagac
5281 cacatcatcg aaaccgcaaa catatcatac acaaacgcct gagccctatc tattactctc
5341 atcgctacct ccctgacaag cgcctatagc actcgaataa ttcttctcac cctaacaggt
5401 caacctcgct tcccc
//