LOCUS HSU19977 1306 bp mRNA linear HUM 16-AUG-1995
DEFINITION Human preprocarboxypeptidase A2 (proCPA2) mRNA, complete cds.
ACCESSION U19977
VERSION U19977.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1306)
AUTHORS Catasus,L., Vendrell,J., Aviles,F.X., Carreira,S., Puigserver,A.
and Billeter,M.
TITLE The sequence and conformation of human pancreatic
procarboxypeptidase A2. cDNA cloning, sequence analysis, and
three-dimensional model
JOURNAL J. Biol. Chem. 270 (12), 6651-6657 (1995)
PUBMED 7896805
REFERENCE 2 (bases 1 to 1306)
AUTHORS Aviles,F.X.
TITLE Direct Submission
JOURNAL Submitted (19-JAN-1995) Francesc X. Aviles, Bioquimica i Biologia
Molecular, Universitat Autonoma de Barcelona, Facultat Ciencies,
Campus Bellaterra. U.A.B., Bellaterra, Barcelona. Catalunya, 08193
Bellaterra, Spain
FEATURES Location/Qualifiers
source 1..1306
/db_xref="H-InvDB:HIT000218542"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="pancreas"
gene 1..1306
/gene="proCPA2"
5'UTR <1..4
/gene="proCPA2"
CDS 5..1258
/gene="proCPA2"
/codon_start=1
/product="preprocarboxypeptidase A2"
/protein_id="AAA74425.1"
/translation="MRLILFFGALFGHIYCLETFVGDQVLEIVPSNEEQIKNLLQLEA
QEHLQLDFWKSPTTPGETAHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENE
EMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLK
FSTGGDKPAIWLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPV
TNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGP
SANSEVEVKSIVDFIKSHGKVKAFIILHSYSQLLMFPYGYKCTKLDDFDELSEVAQKA
AQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPAR
QILPTAEETWLGLKAIMEHVRDHPY"
sig_peptide 5..52
/gene="proCPA2"
mat_peptide 53..1255
/gene="proCPA2"
/product="procarboxypeptidase A2"
3'UTR 1259..>1306
/gene="proCPA2"
regulatory 1283..1288
/regulatory_class="polyA_signal_sequence"
/gene="proCPA2"
BASE COUNT 348 a 313 c 325 g 320 t
ORIGIN
1 ggccatgagg ttgatcctgt tttttggtgc cctttttggg catatctact gtctagaaac
61 atttgtggga gaccaagttc ttgagattgt accaagcaat gaagaacaaa ttaaaaatct
121 gctacaattg gaggctcaag aacatctcca gcttgatttt tggaaatcac ccaccacccc
181 aggggagaca gcccacgtcc gagttccctt cgtcaacgtc caggcagtca aagtgttctt
241 ggagtcccag ggaattgcct attccatcat gattgaagac gtgcaggtcc tgttggacaa
301 agagaatgaa gaaatgcttt ttaataggag aagagaacgg agtggtaact tcaattttgg
361 ggcctaccat accctggaag agatttccca agaaatggat aacctcgtgg ctgagcaccc
421 tggtctagtg agcaaagtga atattggctc ttcttttgag aaccggccta tgaacgtgct
481 caagttcagc accggaggag acaagccagc tatctggctg gatgctggga tccatgctcg
541 agagtgggtt acacaagcta cggcactttg gacagcaaat aagattgttt ctgattatgg
601 aaaggaccca tccatcactt ccattctgga cgccctggat atcttcctcc tgccagtcac
661 aaaccctgat ggatacgtgt tctctcaaac caaaaatcgt atgtggcgga agacccggtc
721 caaggtatct ggaagcctct gtgttggtgt ggatcctaac cggaactggg atgcaggttt
781 tggaggacct ggagccagca gcaacccttg ctctgattca taccacggac ccagtgccaa
841 ctctgaagtt gaagtgaaat ccatagtgga cttcatcaag agtcatggaa aagtcaaggc
901 cttcattatc ctccacagct attcccagct gctgatgttc ccctatgggt acaaatgtac
961 caagttagat gactttgatg agctgagtga agtggcccaa aaggctgccc aatctctgag
1021 aagcctgcat ggcaccaagt acaaagtggg accaatctgc tctgtcatct accaagccag
1081 tggaggaagc attgactggt cctatgatta tggcatcaag tactcatttg cctttgaact
1141 gagagacaca gggcgctacg gcttcctctt gccagcccgt cagatcctgc ccacagccga
1201 ggagacctgg cttggcttga aggcaatcat ggagcatgtg cgagaccacc cctattaggg
1261 ccctggggaa gaaacaagag ccattaaaat ctctttggtt tgaagc
//