LOCUS HSU19721 3048 bp mRNA linear HUM 04-MAR-1995
DEFINITION Human peroxisomal targeting signal receptor 1 (PXR1) mRNA, complete
cds.
ACCESSION U19721
VERSION U19721.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3048)
AUTHORS Dodt,G., Braverman,N., Wong,C., Moser,A., Moser,H.W., Watkins,P.,
Valle,D. and Gould,S.J.
TITLE Mutations in the PTS1 receptor gene, PXR1, define complementation
group 2 of the peroxisome biogenesis disorders
JOURNAL Nat. Genet. 9 (2), 115-125 (1995)
PUBMED 7719337
REFERENCE 2 (bases 1 to 3048)
AUTHORS Gould,S.J.
TITLE Direct Submission
JOURNAL Submitted (10-JAN-1995) Stephen J. Gould, Biological Chemistry, The
Johns Hopkins University School of Medicine, 725 North Wolfe
Street, Baltimore, MD 21205, USA
FEATURES Location/Qualifiers
source 1..3048
/db_xref="H-InvDB:HIT000218524"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..3048
/gene="PXR1"
CDS 15..1823
/gene="PXR1"
/codon_start=1
/product="peroxisomal targeting signal receptor 1"
/protein_id="AAC50103.1"
/translation="MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGA
PASEAASKPLGVASEDELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQA
PQRAPGVADLALSENWAQEFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWA
EEYLEQSEEKLWLGEPEGTATDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEGTSD
AWVDQFTRPVNTSALDMEFERAKSAIESDVDFWDKLQAELEEMAKRDAEAHPWLSDYD
DLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEA
WQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACEILRDW
LRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTSID
PDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAY
RRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMSENI
WSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ"
BASE COUNT 676 a 737 c 884 g 751 t
ORIGIN
1 agctggcggt caccatggca atgcgggagc tggtggaggc cgaatgcggg ggtgccaacc
61 cgctcatgaa gctcgccggg cacttcaccc aggacaaggc ccttcggcag gagggattga
121 ggcctggccc ctggcccccc ggagcaccgg cctctgaggc agcctccaag cctttgggag
181 tagcttctga agatgagttg gtggctgaat tcctgcagga ccagaatgca ccccttgtgt
241 cccgtgcccc tcagaccttc aagatggatg acctcctggc tgagatgcag cagattgagc
301 agtcaaactt ccgccaggct ccccagagag cccctggtgt ggcagacttg gccttgtctg
361 agaactgggc ccaggagttt cttgcagctg gagatgctgt ggatgtaact caggattata
421 atgagactga ctggtcccaa gaattcatct ctgaagttac agaccccttg tctgtgtccc
481 ctgcccgctg ggctgaggaa tatttggagc aatcagagga gaagctgtgg ctgggagaac
541 ctgagggaac agccaccgat cgctggtatg atgaatatca tcctgaggag gatctgcagc
601 acacggccag tgactttgtg gccaaagtgg atgaccccaa attggctaat tctgagggta
661 catcagatgc ctgggttgac cagttcacaa gaccagtaaa cacatctgcc cttgatatgg
721 agtttgaacg agccaagtca gctatagagt ctgatgtcga tttctgggac aagttgcagg
781 cagagttgga ggagatggca aaacgggatg ctgaggccca cccctggctt tctgactatg
841 atgaccttac gtcagctacc tatgataagg ggtaccagtt tgaggaggag aaccccttgc
901 gtgatcaccc tcagcctttt gaagaagggc tgcggcgcct tcaggagggg gacctgccaa
961 atgctgtgct gctttttgag gcagctgtgc agcaggatcc taagcacatg gaagcttggc
1021 agtatctggg taccacccag gcagagaatg aacaagaact attagccatc agtgcattgc
1081 ggaggtgtct ggagctaaag ccagataacc agacagcact gatggcgctg gctgtgagct
1141 tcaccaacga gtccctgcag cgacaggcct gtgaaatcct acgagactgg ctgcggtaca
1201 caccagccta tgcccatctg gtgacacctg ctgaagaagg ggctggtggg gcaggactgg
1261 gccccagcaa gcgtatcctg ggatctctct tgtctgactc cctgtttctt gaagtgaaag
1321 agctcttcct ggcagctgtg cggctggacc ctacctccat tgaccctgat gtgcagtgtg
1381 gcttgggagt ccttttcaac ctgagtgggg agtatgacaa ggccgtggac tgcttcacag
1441 ctgccctcag cgttcgtccc aatgactatt tgctgtggaa taagctaggc gccaccctgg
1501 ccaatggaaa ccagagtgaa gaagcagtag ctgcgtaccg ccgggccctc gagctccagc
1561 ctggctatat ccggtcccgc tataacctgg gcatcagctg catcaacctc ggggctcacc
1621 gggaggctgt ggagcacttt ctggaggccc tgaacatgca gaggaaaagc cggggccccc
1681 ggggtgaagg aggtgccatg tcggagaaca tctggagcac cctgcgtttg gcattgtcta
1741 tgttaggcca gagcgatgcc tatggggcag ccgacgcgcg ggatctgtcc accctcctaa
1801 ctatgtttgg cctgccccag tgacagtggg acgggctgcc ctgtgagtgt ccacctggag
1861 ggatcccgct tttggatgtg attccctctc cccaaatggg cctaccaagg ggcgggcttg
1921 atgaccataa gcggtacggc ctttcaggag ctgcctcaac gtaggggtgg gtagtctgtg
1981 ttctagttcc tacataattg taggaaaatg agctgtgtca tctctgagtc ccttggtaat
2041 tcaagggctg tacatccagc tacagatctc tctgctcatc atgccctttc ttggtgctgc
2101 tttttgggta ggaccccacg atttagggta actgttatca tcagctgcca tttctgatag
2161 gtctaccaca tctgtaatgt catgtccttt cccccacttt tactgggaat tgatagtcca
2221 gcttccttgg gcagtgtaag taggaggttc atctcctgtg cgcctctaat gtctgtctgg
2281 atgggatgtg ttaggagttg gcctgttggg ttgaattgtt gatttggctg agcagagctg
2341 agttttggta ggagtgctca tggttctgtc attcttggac ctctcctggc tgagctctga
2401 ttccctgtga gcacgatgct gatgcaatag tcctgtgtca tcactgcagc ggtcctcagg
2461 agctgccagg gccaattgct acagagtgtc tgggtgtgtg gcataggagg aaggtttgct
2521 tgtgaaatga ggctgggtgg gagcggggag ggactagatc agaagagatc aagggctcta
2581 ttcaggaacg ttggtgggag gacagagcaa gtgggaaggg ggtatggtga gtgcggcaat
2641 ccctcatcct cttagaagca cctgtgaatg ggaattgagc caactgttat agaaaattgg
2701 ttcagaaagt gcaatcttgc cagatttcta gcaaataggt tcagtgttac cataagcctt
2761 tgctgtactt cttgaaatgt ttctagggga gagcattgga aaatcccctt cccccatcta
2821 gatcgaagga agatgaggga gcagcttgga ttcttctcag ttgtcccctg catggggaga
2881 tacactaacc cccagaaatg actgctaagc ctcttgcctt gtctttagta gctaatgatc
2941 agagagattt tttttttaaa ctaccatggt cccaggattc catcctgaaa tttatttttc
3001 tttgtatgaa tatgtgtaaa tgatttaaaa ataaaactgt aaaatatt
//