LOCUS HSU19523 2921 bp mRNA linear HUM 09-OCT-1996
DEFINITION Human GTP cyclohydrolase I mRNA, complete cds.
ACCESSION U19523
VERSION U19523.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2921)
AUTHORS Nomura,T., Ohtsuki,M., Matsui,S., Sumi-Ichinose,C., Nomura,H.,
Hagino,Y., Iwase,K., Ichinose,H., Fujita,K. and Nagatsu,T.
TITLE Isolation of a full-length cDNA clone for human GTP cyclohydrolase
I type 1 from pheochromocytoma
JOURNAL J Neural Transm Gen Sect 101 (1-3), 237-242 (1995)
PUBMED 8695054
REFERENCE 2 (bases 1 to 2921)
AUTHORS Nomura,T.
TITLE Direct Submission
JOURNAL Submitted (05-JAN-1995) Takahide Nomura, Dept. of Pharmacology,
Fujita Health University, School of Medicine, 1-98 Dengakugakubo,
Kutsukake-cho, Toyoake, Aichi, 470-11, Japan
FEATURES Location/Qualifiers
source 1..2921
/db_xref="H-InvDB:HIT000218516"
/organism="Homo sapiens"
/mol_type="mRNA"
/strain="Japanese"
/db_xref="taxon:9606"
/tissue_type="pheochromocytoma"
CDS 149..901
/EC_number="3.5.4.16"
/function="conversion of GTP to
D-erythro-7,8-dihydroneopterin triphosphate"
/codon_start=1
/product="GTP cyclohydrolase I"
/protein_id="AAB16861.1"
/translation="MEKGPVRAPAEKPRGARCSNGFPERDPPRPGPSRPAEKPPRPEA
KSAQPADGWKGERPRSEEDNELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAM
QFFTKGYQETISDVLNDAIFDEDHDEMVIVKDIDMFSMCEHHLVPFVGKVHIGYLPNK
QVLGLSKLARIVEIYSRRLQVQERLTKQIAVAITEALRPAGVGVVVEATHMCMVMRGV
QKMNSKTVTSTMLGVFREDPKTREEFLTLIRS"
BASE COUNT 776 a 589 c 651 g 905 t
ORIGIN
1 ccggctcgga gtgtgatcta agcaggtcgc gtaccttcct caggtgactc cggccacagc
61 ccattgtccg cggccaccgg cggagtttag ccgcagacct cgaagcgccc cggggtcctt
121 cccgaacggc agcggctgcg gcgggtccat ggagaagggc cctgtgcggg caccggcgga
181 gaagccgcgg ggcgccaggt gcagcaatgg gttccccgag cgggatccgc cgcggcccgg
241 gcccagcagg ccggcggaga agcccccgcg gcccgaggcc aagagcgcgc agcccgcgga
301 cggctggaag ggcgagcggc cccgcagcga ggaggataac gagctgaacc tccctaacct
361 ggcagccgcc tactcgtcca tcctgagctc gctgggcgag aacccccagc ggcaagggct
421 gctcaagacg ccctggaggg cggcctcggc catgcagttc ttcaccaagg gctaccagga
481 gaccatctca gatgtcctaa acgatgctat atttgatgaa gatcatgatg agatggtgat
541 tgtgaaggac atagacatgt tttccatgtg tgagcatcac ttggttccat ttgttggaaa
601 ggtccatatt ggttatcttc ctaacaagca agtccttggc ctcagcaaac ttgcgaggat
661 tgtagaaatc tatagtagaa gactacaagt tcaggagcgc cttacaaaac aaattgctgt
721 agcaatcacg gaagccttgc ggcctgctgg agtcggggta gtggttgaag caacacacat
781 gtgtatggta atgcgaggtg tacagaaaat gaacagcaaa actgtgacca gcacaatgtt
841 gggtgtgttc cgggaggatc caaagactcg ggaagagttc ctgactctca ttaggagctg
901 agcttcattc agtgtgtgtg cgttggttgc cgatcgtact gccagtagca ttgtctgtct
961 gtccggtctt gtttgtacat tccattttca attgttacag atgtgaactt tattccttgt
1021 cactaattat atttaaaatt atttctagga agtcaaataa atataataaa gggttgagcc
1081 tctactttct tcttgccacc tttttgtggc aatattaaag tgaactgcta atagtgtaag
1141 tatgtgcaca aaaccactgc cagataacca gaggggcctg ggaagggaga agaattagtg
1201 tatttttttc aaatagtaca gtaatttgcc tcataagcat aggagcattg ggaatgagag
1261 ggaactgtgc ccagtatact gttttttttc ttcctccaat aaaagtggtg tagtgccgaa
1321 agtgctaaaa tatttagtgc ggtattgctc tgtgaattca agttcaacag acttcacttt
1381 ggtcatgttt attaaaccac cagtgacatt taaaaatata tttttagcag tcgtaatgtt
1441 agtcaccaag ggaaggtggt ggaatgtcta tgtttttgat tttactgtga gttaaaaagg
1501 cacatttcta ccttctattg tttttaaatt caagaatagg gaattagttc ctggtgttgt
1561 ttacgagtgt attctcgtgt caacatacag ggatttagac atttaactct ctgtgccttg
1621 ataagaatat catttagagt gtagatactt ttgccttttt aaaaaagcca ttattttatg
1681 agacttagta ctcacactgc aaataactag tcagctcagt tttaacttta taggtttatt
1741 gagtttcctt tgtgtgatcc atgtagatgc ctcaaaatgt ttcttcttct tctttttttt
1801 aatcttataa gatatttttc taagtatttc cagaaacatt tgagagtgcc catcattttc
1861 aggtctgcag aaccatagct tccacgcacc tgaacgagca cagaatgaac tgacggtgga
1921 agacattatg agctgtgtcc aacgttttaa ccaaagcgta tcgtaccaac gatctgtgaa
1981 aatgcactgg aagcttctgg tcccggtttc ctttgtggtc tatgtgggtc ttgtcctcat
2041 tgtaactccg tatagatggt ataggtattt taatcctgga agctgttgcc ttattaatga
2101 ttatcttaaa atttcctcca ttggggcagc gtgggccaaa ttaaaacaaa caaaaccgca
2161 actcctccac agaaacacaa acacagttat tccatgaagt ttagtatttg gttgacatag
2221 tgctcttcaa attcatccca ttaccctaaa agtaataact ttgatgcttg ctttaacttt
2281 agtcccatct ctgccacttt gatgctattt gggttatgat ggggcaagat ggcagaggta
2341 ttgggttttt ttgttttttt ccattcctct ctacttctgt ttcctagctt tttctttctg
2401 gagtttaagt acagtgatgg ttggcttgag taccttttta aatctagccc agtataaaca
2461 ttagcctgct taatatttag acatttatag gtagaattct gagcactcaa ctcatgtttg
2521 gcattttaaa gtaaaaacaa gtgtgacttc gaggaccaaa gaaattgtca gctatacatt
2581 tatctttatg aactcattta tattcctttt taatgactcg ttgttctaac atttcctaga
2641 agtgttctta taaaggtcta atgtatccac aggctgttgt cttattagta aatgcaaagt
2701 aatgactttg tctgttttac tctagtcttt agtacttcaa aattaccttt tcatatccat
2761 gatcttgagt ccatttgggg gatttttaag aatttgatgt atttcaatac actgttcaaa
2821 attaaattgt ttaattttat gtatgagtat gtatgttcct gaagttggtc ctatttaaat
2881 tattaaacta ttgtaacttt aaaaaaaaaa aaaaaaaaaa a
//