LOCUS HSU18918 3901 bp mRNA linear HUM 11-SEP-1995
DEFINITION Human heparan sulfate-N-deacetylase/N-sulfotransferase mRNA, clone
HSST, complete cds.
ACCESSION U18918
VERSION U18918.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3901)
AUTHORS Dixon,J., Loftus,S.K., Gladwin,A.J., Scambler,P.J., Wasmuth,J.J.
and Dixon,M.J.
TITLE Cloning of the human heparan
sulfate-N-deacetylase/N-sulfotransferase gene from the Treacher
Collins syndrome candidate region at 5q32-q33.1
JOURNAL Genomics 26 (2), 239-244 (1995)
PUBMED 7601448
REFERENCE 2 (bases 1 to 3901)
AUTHORS Dixon,M.J.
TITLE Direct Submission
JOURNAL Submitted (20-DEC-1994) Michael J. Dixon, University of Manchester,
School of Biological Sciences, Stopford Building, Oxford Road,
Manchester, M13 9PT, UK
FEATURES Location/Qualifiers
source 1..3901
/db_xref="H-InvDB:HIT000218481"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="5"
/map="5q32-33.1"
/clone="HSST"
/sex="female"
/tissue_type="placenta"
/dev_stage="adult"
5'UTR 1..216
CDS 217..2865
/codon_start=1
/product="heparan
sulfate-N-deacetylase/N-sulfotransferase"
/protein_id="AAA75281.1"
/translation="MPALACLRRLCRHVSPQAVLFLLFIFCLFSVFISAYYLYGWKRG
LEPSADAPEPDCGDPPPVAPSRLLPLKPVQAATPSRTDPLVLVFVESLYSQLGQEVVA
ILESSRFKYRTEIAPGKGDMPTLTDKGRGRFALIIYENILKYVNLDAWNRELLDKYCV
AYGVGIIGFFKANENSLLSAQLKGFPLFLHSNLGLKDCSINPKSPLLYVTRPSEVEKG
VLPGEDWTVFQSNHSTYEPVLLAKTRSSESIPHLGADAGLHAALHATVVQDLGLHDGI
QRVLFGNNLNFWLHKLVFVDAVAFLTGKRLSLPLDRYILVDIDDIFVGKEGTRMKVED
VKALFDTQNELRAHIPNFTFNLGYSGKFFHTGTNAEDAGDDLLLSYVKEFWWFPHMWS
HMQPHLFHNQSVLAEQMALNKKFAVEHGIPTDMGYAVAPHHSGVYPVHVQLYEAWKQV
WSIRVTSTEEYPHLKPARYRRGFIHNGIMVLPRQTCGLFTHTIFYNEYPGGSSELDKI
INGGELFLTVLLNPISIFMTHLSNYGNDRLGLYTFKHLVRFLHSWTNLRLQTLPPVQL
AQKYFQIFSEEKDPLWQDPCEDKRHKDIWSKEKTCDRFPKLLIIGPQKTGTTALYLFL
GMHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYMEFFPIPSNTTSDFYFEKSANYFD
SEVAPRRAAALLPKAKVLTILINPADRAYSWYQHQRAHDDPVALKYTFHEVITAGSDA
SSKLRALQNRCLVPGWYATHIERWLSAYHANQILVLDGKLLRTEPAKVMDMVQKFLGV
TNTIDYHKTLAFDPKKGFWCQLLEGGKTKCLGKSKGRKYPEMDLDSRAFLKDYYRDHN
IELSKLLYKMGQTLPTWLREDLQNTR"
3'UTR 2866..3901
polyA_site 3901
/note="12 A nucleotides"
BASE COUNT 793 a 1245 c 1050 g 813 t
ORIGIN
1 gaaggaagga gcgtgaccag cctgtggact gcgcccctgg ctgggaggaa ggactggggg
61 cccagatcct ccactcccag tgccccacaa gggcgtcgct tcctaagtct ctgtgaattt
121 gttggtcagt ggacgattct cgtgtctcct cctgtgtggg gccttggggt agccagggca
181 ggccgggcct ccgtggccaa ggtctcggag gccaggatgc ctgccctggc atgcctccgg
241 aggctgtgtc ggcacgtgtc cccgcaggct gtccttttcc tgctgttcat cttctgcctg
301 ttcagcgttt tcatctcggc ctactaccta tatggctgga agcgaggcct ggagccctcg
361 gcggatgccc ccgagcctga ctgcggggac ccgccgcctg tggcccccag tcgcctgctg
421 ccactcaagc ctgtgcaggc agccacccct tcccgcacag acccgttggt gctggtcttt
481 gtggagagcc tctactcgca actgggccag gaggtggtgg ccatcctgga gtccagccgc
541 ttcaaatacc gcacagagat tgcgccgggc aagggtgaca tgcccacgct cactgacaag
601 ggccgtggcc gcttcgccct catcatctat gagaacatcc tcaagtatgt caacctggac
661 gcctggaacc gggagctgct ggacaagtac tgtgtggcct acggcgtggg catcattggc
721 ttcttcaagg ccaatgagaa cagcctgctg agtgcgcagc tcaagggctt ccccctgttc
781 ctgcactcaa acctgggcct gaaggactgc agcatcaacc ccaagtcccc gctgctctac
841 gtgacgcgac ctagcgaggt ggagaaaggt gtgctccccg gcgaggactg gacggttttc
901 cagtcaaatc actccaccta tgagccagtg ctgctggcca agacgcgctc gtctgagtcc
961 atcccacacc tgggcgcaga cgccggcctg catgctgcac tgcacgccac tgtggtccag
1021 gacctgggcc tgcacgacgg catccagcgc gtgctgtttg gcaacaacct gaacttctgg
1081 ctgcacaagc ttgtcttcgt ggatgccgtg gccttcctca cggggaagcg cctctccctg
1141 ccattggacc gctacatcct ggtggacatt gatgacatct tcgtgggcaa ggagggcaca
1201 cgcatgaagg tggaggacgt gaaggccctg tttgacacac agaacgaact acgcgcacac
1261 atcccaaact tcaccttcaa cctgggctac tcagggaaat tcttccacac aggtaccaat
1321 gctgaggacg ctggggatga tctgctgctg tcgtatgtga aggagttctg gtggttcccc
1381 cacatgtgga gccacatgca gccccacctt ttccacaacc agtccgtgtt ggccgagcag
1441 atggccttga acaagaagtt cgctgtcgag catggcattc ccacagacat ggggtatgca
1501 gtggcgcccc accactcggg cgtgtacccc gtgcacgtgc agctgtacga ggcttggaag
1561 caggtgtgga gcatccgcgt gaccagcacg gaggagtacc cccacctgaa gccagcccgc
1621 taccgccgtg gcttcatcca caatggcatc atggttctcc cacggcagac ctgcggcctc
1681 ttcacacaca ccatcttcta caacgagtac cctggcggct ccagtgagct ggacaaaatc
1741 atcaacgggg gcgagctctt cctcaccgtg ctcctcaatc ctatcagcat cttcatgacg
1801 cacctgtcca actatgggaa tgaccgcctg ggcctgtaca ccttcaagca cctggtgcgc
1861 ttcctgcact cctggacgaa cctccggctg cagacactgc cccctgtgca gttggcgcag
1921 aagtacttcc agatcttctc cgaggagaag gacccgctct ggcaggaccc ctgcgaggac
1981 aaacgtcaca aagacatctg gtccaaggag aagacgtgtg accgcttccc aaagctcctc
2041 atcatcggcc cccagaaaac aggcaccact gccctctacc tgttcctggg catgcaccct
2101 gacctaagca gcaactaccc cagctctgag acctttgagg agatccagtt ttttaatggc
2161 cacaactatc acaaaggcat cgactggtac atggagttct tccccatccc ttccaacacc
2221 acctccgact tctactttga gaaaagcgcc aactactttg attcagaagt ggcgccccgg
2281 cgggcagcag ccctcttgcc caaagccaag gtcctgacca tcctcatcaa ccccgcggac
2341 cgggcctatt cctggtacca gcaccagcga gcccatgacg acccagtggc cctaaagtac
2401 accttccatg aggtgattac cgccggctct gacgcatcct cgaagctgcg tgccctccag
2461 aaccgctgcc tggtccctgg ctggtacgcc acccacatcg agcgctggct cagtgcctat
2521 cacgccaacc agattctggt cttggatggc aaactgcttc gcacagaacc tgccaaagtg
2581 atggacatgg tgcagaagtt ccttggggtg accaacacca ttgactacca caaaaccttg
2641 gcgtttgatc caaagaaagg attttggtgc caactgcttg aaggaggaaa aaccaagtgt
2701 ctgggcaaaa gcaagggccg gaaatatccc gagatggact tggattcccg agccttcctg
2761 aaggactatt accgggacca caacatcgag ctctccaagc tgctgtataa gatgggccag
2821 acacttccca cttggctacg agaggacctc cagaacacca ggtagccgtg gccaccacag
2881 ccagactgaa cgtttgtgaa agctgggaca tcccaccaca cgctgagcca gacctgcaga
2941 gtgggaagct ggaccagggc agctgcgcac ttatgagcaa tactctgtgg aggtctggtg
3001 gggctggggg agcacccagg cggatctgca agcacctcgg agcacccacc gctgggtctg
3061 cggcctaagg gacctccctc gccagcagag gtccattccg ttcccagctg ctcctgggga
3121 ggccgcttcc tggtaggagg gagtccacga gactcttttc tgtccctcac tgtgttccgc
3181 cgactgtccc ctctcgtcac ccatcactcc ctgcttccgc agggcgcccc tcagtattcg
3241 ctgccatatg tccctgtcct ccaggctgta ggggaggaga gcctggccgg gggagacaga
3301 ctggacattt ccctgtttcg agccaggctc ttccaagggg ccagctgggt ccccggagtc
3361 agtcctaggc tggatgggag ggtggccccc tcaagaggac tcccagcctc cacatctggt
3421 tcctaccttc acatctcacc ctcccgttct ggggaagaat ttctggttcc tacagtatcc
3481 actccatcct caaggcttcc cgcagggcct tggggcactg ccttgccatc gggcccagtt
3541 ctccgggccc cacctgcacc cctttcttcc ccctgggata tgatgtgtgg tgtttcctgt
3601 ggtaaaagac tgaggcaggc caggggtctg ccagtaacat gttcccatgt acagacacgg
3661 tccccacacc ctcccagcct caggcccagg cagacatggg cgagctggtg agactgccag
3721 ccacggcttt gcttagccac ctgtggccga gggctctcag agaccccctt aacctcccaa
3781 atactaagaa gctaaaatat tttaatattt tgtttttttt tttcttggtg ccagagttta
3841 taccctgggt gctggggtcg cactgtgtta tatatatata tatatatata tataatgtgt
3901 a
//