LOCUS HSU18728 1729 bp mRNA linear HUM 17-JAN-1996
DEFINITION Human lumican mRNA, complete cds.
ACCESSION U18728
VERSION U18728.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1729)
AUTHORS Grover,J., Chen,X.N., Korenberg,J.R. and Roughley,P.J.
TITLE The human lumican gene. Organization, chromosomal location, and
expression in articular cartilage
JOURNAL J. Biol. Chem. 270 (37), 21942-21949 (1995)
PUBMED 7665616
REFERENCE 2 (bases 1 to 1729)
AUTHORS Grover,J.
TITLE Direct Submission
JOURNAL Submitted (15-DEC-1994) Judy Grover, Genetics Unit, Shriners'
Hospital for Crippled Children, 1529 Cedar Ave., Montreal, Quebec,
Canada, H3G 1A6
FEATURES Location/Qualifiers
source 1..1729
/db_xref="H-InvDB:HIT000218463"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="hp-1, hac-1, hac-2, hfi-2"
/tissue_type="cartilage, placenta, intestine"
5'UTR 1..80
CDS 81..1097
/experiment="experimental evidence, no additional details
recorded"
/codon_start=1
/product="lumican"
/protein_id="AAA85268.1"
/translation="MSLSAFTLFLALIGGTSGQYYDYDFPPSIYGQSSPNCAPECNCP
ESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNVL
ENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGLVN
LTFIHLQHNRLKEDAVSAAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKIS
NIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIPTVNENL
ENYYLEVNQLEKFDIKSFCKILGPLSYSKIKHLRLDGNRISETSLPPDMYECLRVANE
VTLN"
3'UTR 1098..1729
polyA_site 1693..1698
/experiment="experimental evidence, no additional details
recorded"
/note="This is the only consensus polyA signal in the
sequence entry and correlates with mRNA size observed on
Northern blot analysis.; label: polyA_signal"
BASE COUNT 552 a 336 c 297 g 544 t
ORIGIN
1 attcttgtcc atagtgcatc tgctttaaga attaacgaaa gcagtgtcaa gacagtaagg
61 attcaaacca tttgccaaaa atgagtctaa gtgcatttac tctcttcctg gcattgattg
121 gtggtaccag tggccagtac tatgattatg attttccccc atcaatttat gggcaatcat
181 caccaaactg tgcaccagaa tgtaactgcc ctgaaagcta cccaagtgcc atgtactgtg
241 atgagctgaa attgaaaagt gtaccaatgg tgcctcctgg aatcaagtat ctttacctta
301 ggaataacca gattgaccat attgatgaaa aggcctttga gaatgtaact gatctgcagt
361 ggctcattct agatcacaac gttctagaaa actccaagat aaaagggaga gttttctcta
421 aattgaaaca actgaagaag ctgcatataa accacaacaa cctgacagag tctgtgggcc
481 cacttcccaa atctctggag gatctgcagc ttactcataa caagatcaca aagctgggct
541 cttttgaagg attggtaaac ctgaccttca tccatctcca gcacaatcgg ctgaaagagg
601 atgctgtttc agctgctttt aaaggtctta aatcactcga ataccttgac ttgagcttca
661 atcagatagc cagactgcct tctggtctcc ctgtctctct tctaactctc tacttagaca
721 acaataagat cagcaacatc cctgatgagt atttcaagcg ttttaatgca ttgcagtatc
781 tgcgtttatc tcacaacgaa ctggctgata gtggaatacc tggaaattct ttcaatgtgt
841 catccctggt tgagctggat ctgtcctata acaagcttaa aaacatacca actgtcaatg
901 aaaaccttga aaactattac ctggaggtca atcaacttga gaagtttgac ataaagagct
961 tctgcaagat cctggggcca ttatcctact ccaagatcaa gcatttgcgt ttggatggca
1021 atcgcatctc agaaaccagt cttccaccgg atatgtatga atgtctacgt gttgctaacg
1081 aagtcactct taattaatat ctgtatcctg gaacaatatt ttatggttat gtttttctgt
1141 gtgtcagttt tcatagtatc catattttat tactgtttat tacttccatg aattttaaaa
1201 tctgagggaa atgttttgta aacatttatt ttttttaaag aaaagatgaa aggcaggcct
1261 atttcatcac aagaacacac acatatacac gaatagacat caaactcaat gctttatttg
1321 taaatttagt gtttttttat ttctacggtc aaatgatgtg caaaaccttt tactggttgc
1381 atggaaatca gccaagtttt ataatcctta aatcttaatg ttcctcaaag cttggattaa
1441 atacatatgg atgttactct cttgcaccaa attatcttga tacttcaaat ttgtctggtt
1501 aaaaaatagg tggtagatat tgaggccaag aatattgcaa aatacatgaa ccttcatgca
1561 cttaaagaag tatttttaga ataagaattt gcatacttac ctagtgaaac ttttctagaa
1621 ttatttttca ctctaagtca tgtatgttcc tctttgatta tttgcatgtt atgtttaata
1681 agctactagc aaaataaaac atagcaaatg gcaaaaaaaa aaaaaaaaa
//