LOCUS HSU18242 1350 bp mRNA linear HUM 09-JAN-1995
DEFINITION Human calcium modulating cyclophilin ligand (CAMLG) mRNA, complete
cds.
ACCESSION U18242
VERSION U18242.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1350)
AUTHORS Bram,R.J. and Crabtree,G.R.
TITLE Calcium signalling in T cells stimulated by a cyclophilin B-binding
protein
JOURNAL Nature 371 (6495), 355-358 (1994)
PUBMED 7522304
REFERENCE 2 (bases 1 to 1350)
AUTHORS Bram,R.J.
TITLE Direct Submission
JOURNAL Submitted (06-DEC-1994) Richard J. Bram, Experimental Oncology, St.
Jude Children's Research Hospital, 332 N. Lauderdale, Memphis, TN
38105, USA
FEATURES Location/Qualifiers
source 1..1350
/db_xref="H-InvDB:HIT000218441"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="B lymphocyte"
/note="the mRNA is expressed in all tissues with highest
levels in brain, testis, and ovary"
gene 1..1350
/gene="CAMLG"
CDS 37..927
/gene="CAMLG"
/function="activates calcium influx in Jurkat T cells when
overexpressed"
/note="integral membrane protein"
/codon_start=1
/product="calcium modulating cyclophilin ligand"
/protein_id="AAA59420.1"
/translation="MESMAVATDGGERPGVPAGSGLSASQRRAELRRRKLLMNSEQRI
NRIMGFHRPGSGAEEESQTKSKQQDSDKLNSLSVPSVSKRVVLGDSVSTGTTDQQGGV
AEVKGTQLGDKLDSFIKPPECSSDVNLELRQRNRGDLTADSVQRGSRHGLEQYLSRFE
EAMKLRKQLISEKPSQEDGNTTEEFDSFRIFRLVGCALLALGVRAFVCKYLSIFAPFL
TLQLAYMGLYKYFPKSEKKIKTTVLTAALLLSGIPAEVINRSMDTYSKMGEVFTDLCV
YFFTFIFCHELLDYWGSEVP"
BASE COUNT 376 a 280 c 332 g 362 t
ORIGIN
1 cgccactgcc acccctccca gactgtggac gggaggatgg agtcgatggc cgtcgctacc
61 gacggcgggg agaggccggg ggtcccagcg ggctcaggtc tgtcggcttc ccagcgtcgg
121 gcggagctgc gtcggagaaa gctgctcatg aactcggaac agcgcatcaa ccggatcatg
181 ggctttcaca ggcccgggag cggcgcggaa gaagaaagtc aaacaaaatc aaagcagcag
241 gacagtgata aactgaactc cctcagcgtt ccttccgttt caaagcgagt agtgctgggt
301 gattcagtca gtacaggaac aactgaccag cagggtggtg tggccgaggt aaaggggacc
361 caactgggag acaaattgga ctcgttcatt aaaccacctg agtgcagtag tgatgtcaac
421 cttgagctcc ggcagcggaa cagaggggac ctgacagcgg actcggtcca gaggggttcc
481 cgccatggcc tagagcagta cctttccaga ttcgaagaag caatgaagct aaggaaacag
541 ctgattagtg aaaaacccag tcaagaggat ggaaatacaa cagaagaatt tgactctttt
601 cgaatattta gattggtggg atgtgctctt cttgctcttg gagtcagagc ttttgtttgc
661 aaatacttgt ccatatttgc tccatttctt actttacaac ttgcgtacat gggattatac
721 aaatattttc ccaagagtga aaagaagata aagacaacag tactaacagc tgcacttcta
781 ttgtcgggaa ttcctgccga agtgataaat cgatcaatgg atacctatag caaaatgggc
841 gaagtcttca cagatctctg tgtctacttt ttcactttta tcttttgtca tgaactgctt
901 gattattggg gctctgaagt accatgaagc ctgtagaact gagaaggaga agcttacgaa
961 aaaaatcctc ttctatattg cagtgtctct aaaggaggca aattggttta caccttcatg
1021 taattctttt actttagggg ttgtaaagct actttattag atatagaatg gcagattctc
1081 tgatttaaaa gggctgagtt tgtattatta ctgatatgaa gaatagagta ccaatgtcat
1141 taattgattt ttcttgttaa tcagaattcc tattctgtac ctttcctcta acttctcaga
1201 tttgtaattc ttcttttcgg gagctgagct agtgctttta ggagaacaga taaatgtggt
1261 ctcagccagc cctagagact gcttcttgtg tttgtgtcat tctgtcctga gaaatgaagt
1321 catctgaaaa ataaaaatgc agaaacccaa
//