LOCUS HSU16270 2857 bp mRNA linear HUM 19-DEC-1995
DEFINITION Human AMP deaminase isoform L (AMPD2) mRNA, exons 6-18, partial
cds.
ACCESSION U16270
VERSION U16270.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2857)
AUTHORS Van den Bergh,F. and Sabina,R.L.
TITLE Characterization of human AMP deaminase 2 (AMPD2) gene expression
reveals alternative transcripts encoding variable N-terminal
extensions of isoform L
JOURNAL Biochem. J. 312 (Pt 2), 401-410 (1995)
PUBMED 8526848
REFERENCE 2 (bases 1 to 2857)
AUTHORS Sabina,R.L.
TITLE Direct Submission
JOURNAL Submitted (24-OCT-1994) Richard L. Sabina, Biochemistry, Medical
College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI
53226, USA
FEATURES Location/Qualifiers
source 1..2857
/db_xref="H-InvDB:HIT000218339"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="Huce1"
/tissue_type="cerebellum"
/clone_lib="human cerebellum 5'-stretch cDNA (CLONTECH)"
gene 1..2857
/gene="AMPD2"
mRNA <1..>2857
/gene="AMPD2"
/note="alternatively terminated"
CDS <1..1877
/gene="AMPD2"
/EC_number="3.5.4.6"
/codon_start=3
/product="AMP deaminase"
/protein_id="AAC50308.1"
/translation="ALSLQSFCPTTRRYLQQLAEKPLETRTYEQGPDTPVSADAPVHP
PALEQHPYEHCEPSTMPGDLGLGLRMVRGVVHVYTRREPDEHCSEVELPYPDLQEFVA
DVNVLMALIINGPIKSFCYRRLQYLSSKFQMHVLLNEMKELAAQKKVPHRDFYNIRKV
DTHIHASSCMNQKHLLRFIKRAMKRHLEEIVHVEQGREQTLREVFESMNLTAYDLSVD
TLDVHADRNTFHRFDKFNAKYNPIGESVLREIFIKTDNRVSGKYFAHIIKEVMSDLEE
SKYQNAELRLSIYGRSRDEWDKLARWAVMHRVHSPNVRWLVQVPRLFDVYRTKGQLAN
FQEMLENIFLPLFEATVHPASHPELHLFLEHVDGFDSVDDESKPENHVFNLESPLPEA
WVEEDNPPYAYYLYYTFANMAMLNHLRRQRGFHTFVLRPHCGEAGPIHHLVSAFMLAE
NISHGLLLRKAPVLQYLYYLAQIGIAMSPLSNNSLFLSYHRNPLPEYLSRGLMVSLST
DDPLQFHFTKEPLMEEYSIATQVWKLSSCDMCELARNSVLMSGFSHKVKSHWLGPNYT
KEGPEGNDIRRTNVPDIRVGYRYETLCQELALITQAVQSEMLETIPEEAGITMSPGPQ
"
exon <1..117
/gene="AMPD2"
/note="label: exon6"
exon 118..259
/gene="AMPD2"
/note="label: exon7"
exon 260..674
/gene="AMPD2"
/note="label: exon8-10"
exon 675..806
/gene="AMPD2"
/note="label: exon11"
exon 807..1667
/gene="AMPD2"
/note="label: exon12-17"
exon 1668..2857
/gene="AMPD2"
/note="label: exon18"
3'UTR 1877..2857
/gene="AMPD2"
regulatory 2755..2760
/regulatory_class="polyA_signal_sequence"
/gene="AMPD2"
polyA_site 2772
/gene="AMPD2"
BASE COUNT 559 a 850 c 831 g 617 t
ORIGIN
1 tggccctgtc cctgcagagc ttctgcccca ccacccgccg ctacctgcag cagctggctg
61 aaaagcctct ggagacccgg acctatgaac agggccccga cacccctgtg tctgctgatg
121 ccccggtgca cccccctgcg ctggagcagc acccgtatga gcactgtgag ccaagcacca
181 tgcctgggga cctgggcttg ggtctgcgca tggtgcgggg tgtggtgcac gtctacaccc
241 gcagggaacc cgacgagcat tgctcagagg tggagctgcc ataccctgac ctgcaggaat
301 ttgtggctga cgtcaatgtg ctgatggccc tgattatcaa tggccccata aagtcattct
361 gctaccgccg gctgcagtac ctgagctcca agttccagat gcatgtgcta ctcaatgaga
421 tgaaggagct ggccgcccag aagaaagtgc cacaccgaga tttctacaac atccgcaagg
481 tggacaccca catccatgcc tcgtcctgca tgaaccagaa gcatctgctg cgcttcatca
541 agcgggcaat gaagcggcac ctggaggaga tcgtgcacgt ggagcagggc cgtgaacaga
601 cgctgcggga ggtctttgag agcatgaatc tcacggccta cgacctgagt gtggacacgc
661 tggatgtgca tgcggacagg aacactttcc atcgctttga caagtttaat gccaaataca
721 accctattgg ggagtccgtc ctccgagaga tcttcatcaa gacggacaac agggtatctg
781 ggaagtactt tgctcacatc atcaaggagg tgatgtcaga cctggaggag agcaaatacc
841 agaatgcaga gctgcggctc tccatttacg ggcgctcgag ggatgagtgg gacaagctgg
901 cgcgctgggc cgtcatgcac cgcgtgcact cccccaacgt gcgctggctg gtgcaggtgc
961 cccgcctctt tgatgtgtac cgtaccaagg gccagctggc caacttccag gagatgctgg
1021 agaacatctt cctgccactg ttcgaggcca ctgtgcaccc tgccagccac ccggaactgc
1081 atctcttctt agagcacgtg gatggttttg acagcgtgga tgatgagtcc aagcctgaaa
1141 accatgtctt caacctggag agccccctgc ctgaggcgtg ggtggaggag gacaacccac
1201 cctatgccta ctacctgtac tacacctttg ccaacatggc catgttgaac cacctgcgca
1261 ggcagagggg cttccacacg tttgtgctga ggccacactg tggggaggct gggcccatcc
1321 accacctggt gtcagccttc atgctggctg agaacatttc ccacgggctc cttctgcgca
1381 aggcccccgt cctgcagtac ctgtactacc tggcccagat cggcatcgcc atgtctccgc
1441 tcagcaacaa cagcctcttc ctcagctatc accggaatcc gctaccggag tacctgtccc
1501 gcggcctcat ggtctccctg tccactgatg atcccttgca gttccacttc accaaggagc
1561 cgctgatgga ggagtacagc atcgccaccc aggtgtggaa gctcagctcc tgcgatatgt
1621 gtgagctggc ccgcaacagc gtgctcatga gcggcttctc gcacaaggta aagagccact
1681 ggctgggacc caactatacc aaggaaggcc ctgaggggaa tgacatccgc cggaccaatg
1741 tgccagacat ccgcgtgggc taccgctacg agaccctgtg ccaggagctg gcgctcatca
1801 cgcaggcagt ccagagtgag atgctggaga ccattccaga ggaggcgggt atcaccatga
1861 gcccagggcc tcaatgagcc tggtccatga agtgcccacc acatcgcagc acttttacca
1921 cgttttgtcc tcagaccccg cccatgctgt gtggtctctg catgtctcca ttcttctctg
1981 tctctgtctt gcatgtctcc taccatgtca ctgtccctgg gccacccagt gaaagcaaag
2041 cctgggaatc tgctcattgt tgtttgggct caggtattga gcctgatggc ccaggtattg
2101 agggcctccc ctgctggtgg ccctgtcctg ggatcctcag aagcctgact gtcctatggg
2161 cttctccagt gtccacaggg gcttgggatg gttgtggggg gctggcccct ctagcctttc
2221 cggtccttcc tgggcaaatc taagccttgg ccagggcgaa gtttaggccc ctgtcttgtt
2281 catgtagccg aggggcaggc gggggacctc tacacctctg ctgtgggcac ggggctgctg
2341 agggtctgtg gaactccagc agctctgcac tgggtagagc tgggcctaga gctcagtcac
2401 aggcctgggc ttcctggcct gagtgggtag acgcaggcgg cagaggtgct ggaccacatc
2461 tccgccaagt cactgcccag cagccttctc cgtcctgtcc ccagcccacg tgctccttgg
2521 gtgtcagctt cctgtgcctc tgtgggagag gcagctgcct tgtgttatgt ctggggccac
2581 agttgctgca aagtcctgga tctgccactc aaccccggga gtggtgttcc cagtgtggct
2641 cccagagctt tgaccagatt gtgatcccag ctggccccta tgttgtgttc tggactgagg
2701 cctttgctgt gaactgcagt gtttcatacg aaccatcttt cctagtgcat gagaaataaa
2761 gattatttaa gtaatgaggc aggtggggtt tctgttggga gagggaacgc cgtggtggga
2821 ggtggctgtg gatggaggca ccgtgcattc tgagggg
//