LOCUS HSU16261 1700 bp mRNA linear HUM 09-MAR-1996
DEFINITION Human MDA-7 (mda-7) mRNA, complete cds.
ACCESSION U16261
VERSION U16261.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1700)
AUTHORS Jiang,H., Lin,J.J., Su,Z.Z., Goldstein,N.I. and Fisher,P.B.
TITLE Subtraction hybridization identifies a novel melanoma
differentiation associated gene, mda-7, modulated during human
melanoma differentiation, growth and progression
JOURNAL Oncogene 11 (12), 2477-2486 (1995)
PUBMED 8545104
REFERENCE 2 (bases 1 to 1700)
AUTHORS Fisher,P.B.
TITLE Direct Submission
JOURNAL Submitted (24-OCT-1994) Paul B. Fisher, College of Physicians and
Surgeons, Pathology / Urology, Columbia University, 630 W 168th
Street, New York, NY 10032, USA
FEATURES Location/Qualifiers
source 1..1700
/db_xref="H-InvDB:HIT000218336"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="HO-1"
/cell_type="differentiated melanoma cells"
/tissue_type="melanoma"
gene 1..1700
/gene="mda-7"
CDS 275..895
/gene="mda-7"
/experiment="experimental evidence, no additional details
recorded"
/codon_start=1
/product="MDA-7"
/protein_id="AAA91780.1"
/translation="MNFQQRLQSLWTLARPFCPPLLATASQMQMVVLPCLGFTLLLWS
QVSGAQGQEFHFGPCQVKGVVPQKLWEAFWAVKDTMQAQDNITSARLLQQEVLQNVSD
AESCYLVHTLLEFYLKTVFKNYHNRTVEVRTLKSFSTLANNFVLIVSQLQPSQENEMF
SIRDSAHRRFLLFRRAFKQLDVEAALTKALGEVDILLTWMQKFYKL"
polyA_site 1700
/gene="mda-7"
/note="18 A residues"
BASE COUNT 434 a 418 c 391 g 457 t
ORIGIN
1 cttgcctgca aacctttact tctgaaatga cttccacggc tgggacggga accttccacc
61 cacagctatg cctctgattg gtgaatggtg aaggtgcctg tctaactttt ctgtaaaaag
121 aaccagctgc ctccaggcag ccagccctca agcatcactt acaggaccag agggacaaga
181 catgactgtg atgaggagct gctttcgcca atttaacacc aagaagaatt gaggctgctt
241 gggaggaagg ccaggaggaa cacgagactg agagatgaat tttcaacaga ggctgcaaag
301 cctgtggact ttagccagac ccttctgccc tcctttgctg gcgacagcct ctcaaatgca
361 gatggttgtg ctcccttgcc tgggttttac cctgcttctc tggagccagg tatcaggggc
421 ccagggccaa gaattccact ttgggccctg ccaagtgaag ggggttgttc cccagaaact
481 gtgggaagcc ttctgggctg tgaaagacac tatgcaagct caggataaca tcacgagtgc
541 ccggctgctg cagcaggagg ttctgcagaa cgtctcggat gctgagagct gttaccttgt
601 ccacaccctg ctggagttct acttgaaaac tgttttcaaa aactaccaca atagaacagt
661 tgaagtcagg actctgaagt cattctctac tctggccaac aactttgttc tcatcgtgtc
721 acaactgcaa cccagtcaag aaaatgagat gttttccatc agagacagtg cacacaggcg
781 gtttctgcta ttccggagag cattcaaaca gttggacgta gaagcagctc tgaccaaagc
841 ccttggggaa gtggacattc ttctgacctg gatgcagaaa ttctacaagc tctgaatgtc
901 tagaccagga cctccctccc cctggcactg gtttgttccc tgtgtcattt caaacagtct
961 cccttcctat gctgttcact ggacacttca cgcccttggc catgggtccc attcttggcc
1021 caggattatt gtcaaagaag tcattcttta agcagcgcca gtgacagtca gggaaggtgc
1081 ctctggatgc tgtgaagagt ctacagagaa gattcttgta tttattacaa ctctatttaa
1141 ttaatgtcag tatttcaact gaagttctat ttatttgtga gactgtaagt tacatgaagg
1201 cagcagaata ttgtgcccca tgcttcttta cccctcacaa tccttgccac agtgtggggc
1261 agtggatggg tgcttagtaa gtacttaata aactgtggtg ctttttttgg cctgtctttg
1321 gattgttaaa aaacagagag ggatgcttgg atgtaaaact gaacttcaga gcatgaaaat
1381 cacactgtct gctgatatct gcagggacag agcattgggg tgggggtaag gtgcatctgt
1441 ttgaaaagta aacgataaaa tgtggattaa agtgcccagc acaaagcaga tcctcaataa
1501 acatttcatt tcccacccac actcgccagc tcaccccatc atccctttcc cttggtgccc
1561 tccttttttt tttatcctag tcattcttcc ctaatcttcc acttgagtgt caagctgacc
1621 ttgctgatgg tgacattgca cctggatgta ctatccaatc tgtgatgaca ttccctgcta
1681 ataaaagaca acataactca
//