LOCUS HSU16127 3614 bp mRNA linear HUM 04-APR-1996
DEFINITION Human glutamate/kainate receptor subunit (EAA5) mRNA, complete cds.
ACCESSION U16127
VERSION U16127.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3614)
AUTHORS Nutt,S.L., Hoo,K.H., Rampersad,V., Deverill,R.M., Elliott,C.E.,
Fletcher,E.J., Adams,S.L., Korczak,B., Foldes,R.L. and Kamboj,R.K.
TITLE Molecular characterization of the human EAA5 (GluR7) receptor: a
high-affinity kainate receptor with novel potential RNA editing
sites
JOURNAL Recept. Channels 2 (4), 315-326 (1994)
PUBMED 7719709
REFERENCE 2 (bases 1 to 3614)
AUTHORS Kamboj,R.K.
TITLE Direct Submission
JOURNAL Submitted (19-OCT-1994) Rajender K. Kamboj, Allelix
Biopharmaceuticals Inc., 6850 Goreway Drive, Mississauga, Ontario
L4V 1V7, Canada
FEATURES Location/Qualifiers
source 1..3614
/db_xref="H-InvDB:HIT000218332"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="RKCS5F131, RKCS5F81, RKCAG132, RKCAG112"
/tissue_type="brain"
/clone_lib="Stratagene #936206"
/dev_stage="fetus"
gene 1..3614
/gene="EAA5"
5'UTR <1..18
/gene="EAA5"
/experiment="experimental evidence, no additional details
recorded"
CDS 19..2778
/gene="EAA5"
/function="glutamate/kainate receptor"
/experiment="experimental evidence, no additional details
recorded"
/codon_start=1
/product="EAA5"
/protein_id="AAB60407.1"
/translation="MTAPWRRLRSLVWEYWAGLLVCAFWIPDSRGMPHVIRIGGIFEY
ADGPNAQVMNAEEHAFRFSANIINRNRTLLPNTTLTYDIQRIHFHDSFEATKKACDQL
ALGVVAIFGPSQGSCTNAVQSICNALEVPHIQLRWKHHPLDNKDTFYVNLYPDYASLS
HAILDLVQYLKWRSATVVYDDSTGLIRLQELIMAPSRYNIRLKIRQLPIDSDDSRPLL
KEMKRGREFRIIFDCSHTMAAQILKQAMAMGMMTEYYHFIFTTLDLYALDLEPYRYSG
VNLTGFRILNVDNPHVSAIVEKWSMERLQAAPRAESGLLDGVMMTDAALLYDAVHIVS
VCYQRAPQMTVNSLQCHRHKAWRFGGRFMNFIKEAQWEGLTGRIVFNKTSGLRTDFDL
DIISLKEDGLEKVGVWSPADGLNITEVAKGRGPNVTDSLTNRSLIVTTVLEEPFVMFR
KSDRTLYGNDRFEGYCIDLLKELAHILGFSYEIRLVEDGKYGAQDDKGQWNGMVKELI
DHKADLAVAPLTITHVREKAIDFSKPFMTLGVSILYRKPNGTNPSVFSFLNPLSPDIW
MYVLLAYLGVSCVLFVIARFSPYEWYDAHPCNPGSEVVENNFTLLNSFWFGMGSLMQQ
GSVLMPKALSTRIIGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKI
EYGAVKDGATMTFFKKSKISTFEKMWAFMSRKPSALVKNNEEGIQRALTADYALLMES
TTIEYVTQRNCNLTQIGGLIDSKGYGIGTPMGSPYRDKITIAILQLQEEDKLHIMKEK
WWRGSGCPEEENKEASALGIQKIGGIFIVLAAGLVLSVLVAVGEFVYKLRKTAEREQR
SFCSTVADEIRFSLTCQRRVKHKPQPPMMVKTDAVINMHTFNDRRLPGKDSMACSTSL
APVFP"
misc_difference 1073
/gene="EAA5"
/note="RKCAG132"
/replace="a"
3'UTR 2778..>3614
/gene="EAA5"
/experiment="experimental evidence, no additional details
recorded"
BASE COUNT 811 a 1077 c 988 g 738 t
ORIGIN
1 cctcggcggc gcccaacgat gaccgctccc tggcggcgcc tccggagtct ggtttgggaa
61 tactgggccg ggctcctcgt gtgcgccttc tggatcccgg actcgcgcgg gatgccccac
121 gtcatccgga tcggaggaat cttcgagtat gcggacggcc ccaacgccca ggtcatgaat
181 gccgaggagc atgcctttcg attttctgcc aacatcatca acaggaacag gactctgctg
241 cccaacacaa ccttgaccta tgacatacag aggattcact tccatgacag cttcgaggcg
301 accaaaaagg cctgtgacca gctggcactg ggcgtggtgg cgatcttcgg cccatcacag
361 ggctcctgca ccaatgccgt ccagtccatc tgcaatgccc tggaggtgcc ccacatccag
421 ctgcgttgga agcaccaccc gctggacaac aaggacacct tctacgtgaa cctctacccc
481 gactacgcct cgctcagcca tgccatcctc gacctggtcc agtacctcaa gtggcggtca
541 gccaccgtgg tctatgacga cagtacaggg ctcatccgac tgcaggagct catcatggcc
601 ccatcaagat acaacatccg cctgaagatc cgtcagctcc ccatcgactc tgacgactcg
661 cgccccttgc tcaaggagat gaagcgaggc cgggaattcc gcattatctt cgactgcagc
721 cacactatgg cggcccagat cctcaagcag gccatggcca tgggcatgat gactgagtac
781 taccacttca tcttcaccac tctggatctc tacgctttag acctggagcc ctaccgctac
841 tcaggcgtga acctgacagg attccggatt ctcaatgtgg acaacccaca cgtctcggcc
901 attgtggaga agtggtccat ggagcggctg caggcagctc cccgggccga gtctggcctg
961 ctggatggag tgatgatgac tgatgcagcc ttactgtacg acgccgtcca tatcgtgtcc
1021 gtgtgctacc agcgggcacc acagatgacc gtgaactccc tgcagtgcca tcggcacaag
1081 gcctggcgct ttggcggccg cttcatgaac ttcatcaagg aggctcaatg ggaaggatta
1141 actggacgaa ttgttttcaa caaaactagt ggcttgcgga cggattttga tctggacatc
1201 atcagcctga aagaggatgg cctggagaag gttggggtgt ggagtcctgc cgacgggctc
1261 aacatcactg aggttgccaa aggccgaggc cctaatgtca ccgactctct gacaaacaga
1321 tcactcattg tcaccacagt gctggaggag cccttcgtca tgtttcggaa atcagacagg
1381 acgctatatg ggaatgaccg gttcgagggc tactgcatcg acctgctaaa ggagctggcc
1441 cacatccttg gtttctccta tgagatccgg ctggtggagg acggcaagta cggggcacag
1501 gatgacaagg gccagtggaa cggcatggtc aaggagctca tcgaccacaa ggcagatctg
1561 gccgtggccc ccctgaccat cacccatgtt cgagagaagg ccatcgactt ctccaagccc
1621 ttcatgacac ttggtgtgag catcctgtat cgaaagccca atggcaccaa ccccagcgtc
1681 ttctccttcc tcaatcccct gtccccagac atctggatgt atgttctcct cgcctacctg
1741 ggggtcagct gtgtcctctt cgtcatcgcc aggttcagcc cttatgagtg gtacgatgct
1801 cacccctgca accctggctc cgaggtggtg gaaaataact tcactctgct taacagcttc
1861 tggtttggaa tgggatccct gatgcagcaa gggtctgtgc tgatgcccaa agccctgtcc
1921 acacgcatca ttggtggcat ctggtggttc tttacgctca tcatcatctc ttcctacacg
1981 gccaacctgg ctgcctttct gaccgtggag cgcatggaat cacccattga ctctgctgat
2041 gacctggcca agcaaaccaa aatcgagtat ggggctgtca aggatggggc caccatgacc
2101 ttcttcaaga aatccaagat ctccaccttc gagaagatgt gggccttcat gagcaggaag
2161 ccatcggcgc tggtgaagaa caacgaggag ggcatccaga gggccctgac ggccgactac
2221 gcgctgctca tggagtccac caccatcgag tacgtcacgc agaggaactg caacctcacc
2281 cagatcgggg gcctcattga ctccaagggc tacggcatcg gcacgcccat gggctcccca
2341 taccgggaca agatcaccat cgccatcctg cagcttcagg aggaggacaa gctgcatatc
2401 atgaaggaga agtggtggcg gggcagcggg tgtcctgagg aggaaaacaa agaggccagt
2461 gccctgggga tccagaagat cgggggcatc ttcattgtcc tggccgccgg gctggtcctc
2521 tctgtgctgg tggccgtggg cgagtttgtg tacaagctcc gcaaaacagc agagagagag
2581 cagcgttcct tctgcagcac cgtggccgat gagatccgtt tctcccttac ctgccagcgt
2641 cgagtcaagc acaagcctca gcctcccatg atggtcaaga ctgacgccgt catcaacatg
2701 cacacattca atgaccgccg gcttcccggc aaggacagca tggcctgcag cacatcctta
2761 gcccctgtgt tcccctaggc acaactgggg tggggacctc aggcctgggg gctgggcaga
2821 ggaaagcaaa ggagattgga aggaacgtcc cctgtacccg cactgggctt ggggaccaga
2881 gctgccacct gcctgttggg ccaggagcct cctgccctta cctgccagga agccagcagg
2941 ctctcaggcc agctgcttgg gcttcatcct cctcagatct tctgtgggtt tctaaagctg
3001 ccagccgaga tagccaaggc caaaggaagc acatgcctct ctcaggccaa actcacctgc
3061 ccctcaactc tcctccagag tcagaagttt ctgccgcagc cctgcagagg gcacagaaaa
3121 tggaagacag ctcttatatt gccatttctt ccacaagagc ccaggcctcc tacagcttga
3181 ccgtgaggcc agagacacaa cttcggcgcc ttaaggatgt tctagcatgg ctgccaatgg
3241 gagctcatgg tgagggatac ccatcccata tgcctgggca gaaggaagac ttcatccctc
3301 tggggctgtt cacgtggtcc taatcttctg aacttggcgc tgcccctggc agcccctgtt
3361 ctggcagagt tgaagacaga gctacacagg ggaaaagagg agtttggggt atgggagaga
3421 agagaatgca caaacagagg ccgccatttt ggattcttat ggacaatgac ccagtggttc
3481 ctaatcctct aggaggtctc taagaatata agtgggggag tggccacaga aaattcttct
3541 ccactttcta gccagaggag agaggacccc ctgaatttct cacaaaggat gcccaaagat
3601 gcagccggta tttg
//