LOCUS HSU15555 1550 bp mRNA linear HUM 25-NOV-1996
DEFINITION Human serine palmitoyltransferase (LCB2) mRNA, partial cds.
ACCESSION U15555
VERSION U15555.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 26 to 253)
AUTHORS Takeda,J., Yano,H., Eng,S., Zeng,Y. and Bell,G.I.
TITLE A molecular inventory of human pancreatic islets: sequence analysis
of 1000 cDNA clones
JOURNAL Hum. Mol. Genet. 2 (11), 1793-1798 (1993)
PUBMED 7506601
REFERENCE 2 (bases 1 to 1541)
AUTHORS Nagiec,M.M., Lester,R.L. and Dickson,R.C.
TITLE Sphingolipid synthesis: identification and characterization of
mammalian cDNAs encoding the Lcb2 subunit of serine
palmitoyltransferase
JOURNAL Gene 177 (1-2), 237-241 (1996)
PUBMED 8921873
REFERENCE 3 (bases 1 to 1550)
AUTHORS Nagiec,M.M.
TITLE Direct Submission
JOURNAL Submitted (05-OCT-1994) M. Marek Nagiec, University of Kentucky,
Biochemistry, 800 Rose Str., Lexington, KY 40536-0084, USA
FEATURES Location/Qualifiers
source 1..1550
/db_xref="H-InvDB:HIT000218308"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="hbc176"
/tissue_type="pancreatic islet"
gene 1..1550
/gene="LCB2"
CDS <1..1237
/gene="LCB2"
/EC_number="2.3.1.50"
/codon_start=2
/product="serine palmitoyltransferase"
/protein_id="AAC50871.1"
/translation="NTLARETPMLVAVLTYVGYGVLTLFGYLRDFLRYWRIEKCHHAT
EREEQKDFVSLYQDFENFYTRNLYMRIRDNWNRPICSVPGARVDIMERQSHDYNWSFK
YTGNIIKGVINMGSYNYLGFARNTGSCQEAAAKVLEEYGAGVCSTRQEIGNLDKHEEL
EELVARFLGVEAAMAYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATI
RIFKHNNMQSLEKLLKDAIVYGQPRTRRPWKKILILVEGIYSMEGSIVRLPEVIALKK
KYKAYLYLDEAHSIGALGPTGRGVVEYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKE
LIDYLRTHSHSAVYATSLSPPVVEQIITSMKCIMGQDGTSLGNGITIHEVVQTRNTYH
RFSPLSPVFSHQCLWIMLP"
BASE COUNT 455 a 302 c 367 g 426 t
ORIGIN
1 caacacgttg gcacgagaaa caccaatgct ggttgctgtg ctcacgtatg tggggtatgg
61 cgtactcacc ctctttggat atcttcgaga tttcttgagg tattggagaa ttgaaaagtg
121 tcaccatgca acagaaagag aagaacaaaa ggactttgtg tcattgtatc aagattttga
181 aaacttttat acaaggaatc tgtacatgag gataagagac aactggaatc ggccaatctg
241 tagtgtgcct ggagccaggg tggacatcat ggagagacag tctcatgatt ataactggtc
301 cttcaagtat acagggaata taataaaggg tgttataaac atgggttcct acaactatct
361 tggatttgca cggaatactg gatcatgtca agaagcagcc gccaaagtcc ttgaggagta
421 tggagctgga gtgtgcagta ctcggcagga aattggaaac ctggacaagc atgaagaact
481 agaggagctt gtagcaaggt tcttaggagt agaagctgct atggcgtatg gcatgggatt
541 tgcaacgaat tcaatgaaca ttcctgctct tgttggcaaa ggttgcctga ttctgagtga
601 tgaactgaac catgcatcac tggttctggg agccagactg tcaggagcaa ccattagaat
661 cttcaaacac aacaatatgc aaagcctaga gaagctattg aaagatgcca ttgtttatgg
721 tcagcctcgg acacgaaggc cctggaagaa aattctcatc cttgtggaag gaatatatag
781 catggaggga tctattgttc gtcttcctga agtgattgcc ctcaagaaga aatacaaggc
841 atacttgtat ctggatgagg ctcacagcat tggcgccctg ggccccacag gccggggtgt
901 ggtggagtac tttggcctgg atcccgagga tgtggatgtt atgatgggaa cgttcacaaa
961 gagttttggt gcttctggag gatatattgg aggcaagaag gagctgatag actacctgcg
1021 aacacattct catagtgcag tgtatgccac gtcattgtca cctcctgtag tggagcagat
1081 catcacctcc atgaagtgca tcatggggca ggatggcacc agccttggta atggcatcac
1141 tattcatgaa gttgtccaaa caagaaatac ctatcatcgt ttctctcctt tatcccctgt
1201 atttagtcac cagtgcctat ggatcatgct tccttaatat ctttgaacct gtttacttct
1261 ccatatctca ttgttattta cttgacttag atttctgtcc actttcacct ggttttaata
1321 gccagccagt cataatagta gaggaatcag tcaagcaaaa atgctttgga agaattaaat
1381 aagcaatgct gaacatcagg aattgtagat atccgtacag agagttccag taaaatttta
1441 tgagtccacg accccttttc taagcagtct ggtccatgtt ggtctcatac ctcatatgca
1501 ggattcattc attcattaaa tatttgtttc ataaaaaaaa aaaaaaaaaa
//