LOCUS HSU13737 2635 bp mRNA linear HUM 14-APR-1995
DEFINITION Human cysteine protease CPP32 isoform alpha mRNA, complete cds.
ACCESSION U13737
VERSION U13737.1
KEYWORDS cysteine protease; interleukin 1-beta converting enzyme; apoptotic
protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2635)
AUTHORS Fernandes-Alnemri,T., Litwack,G. and Alnemri,E.S.
TITLE CPP32, a novel human apoptotic protein with homology to
Caenorhabditis elegans cell death protein Ced-3 and mammalian
interleukin-1 beta-converting enzyme
JOURNAL J. Biol. Chem. 269 (49), 30761-30764 (1994)
PUBMED 7983002
REFERENCE 2 (bases 1 to 2635)
AUTHORS Fernandes-Alnemri,T.
TITLE Direct Submission
JOURNAL Submitted (17-AUG-1994) Teresa Fernandes-Alnemri, Pharmacology,
Thomas Jefferson University, Jefferson Cancer Institute, 233, S.
Tenth Street, Philadelphia, PA 19107, USA
FEATURES Location/Qualifiers
source 1..2635
/db_xref="H-InvDB:HIT000218149"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="J1.1 EcoRI/XhoI fragment"
/cell_line="Jurkat"
/cell_type="T-lymphocyte"
/clone_lib="Human Jurkat T-lymphocyte lambda Uni-ZAP XR
cDNA library"
CDS 225..1058
/note="new member of the interleukin 1-beta converting
enzyme gene family of cysteine proteases"
/codon_start=1
/product="cysteine protease CPP32 isoform alpha"
/protein_id="AAA65015.1"
/translation="MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEM
GLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRD
VSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFII
QACRGTELDCGIETDSGVDDDMACHKIPVDADFLYAYSTAPGYYSWRNSKDGSWFIQS
LCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFY
H"
polyA_site 2635
/note="19 A residues"
BASE COUNT 815 a 465 c 569 g 786 t
ORIGIN
1 gaattcggca cgaggggtgc tattgtgagg cggttgtaga agagtttcgt gagtgctcgc
61 agctcatacc tgtggctgtg tatccgtggc cacagctggt tggcgtcgcc ttgaaatccc
121 aggccgtgag gagttagcga gccctgctca cactcggcgc tctggttttc ggtgggtgtg
181 ccctgcacct gcctcttccc ccattctcat taataaaggt atccatggag aacactgaaa
241 actcagtgga ttcaaaatcc attaaaaatt tggaaccaaa gatcatacat ggaagcgaat
301 caatggactc tggaatatcc ctggacaaca gttataaaat ggattatcct gagatgggtt
361 tatgtataat aattaataat aagaattttc ataaaagcac tggaatgaca tctcggtctg
421 gtacagatgt cgatgcagca aacctcaggg aaacattcag aaacttgaaa tatgaagtca
481 ggaataaaaa tgatcttaca cgtgaagaaa ttgtggaatt gatgcgtgat gtttctaaag
541 aagatcacag caaaaggagc agttttgttt gtgtgcttct gagccatggt gaagaaggaa
601 taatttttgg aacaaatgga cctgttgacc tgaaaaaaat aacaaacttt ttcagagggg
661 atcgttgtag aagtctaact ggaaaaccca aacttttcat tattcaggcc tgccgtggta
721 cagaactgga ctgtggcatt gagacagaca gtggtgttga tgatgacatg gcgtgtcata
781 aaataccagt ggatgccgac ttcttgtatg catactccac agcacctggt tattattctt
841 ggcgaaattc aaaggatggc tcctggttca tccagtcgct ttgtgccatg ctgaaacagt
901 atgccgacaa gcttgaattt atgcacattc ttacccgggt taaccgaaag gtggcaacag
961 aatttgagtc cttttccttt gacgctactt ttcatgcaaa gaaacagatt ccatgtattg
1021 tttccatgct cacaaaagaa ctctattttt atcactaaag aaatggttgg ttggtggttt
1081 tttttagttt gtatgccaag tgagaagatg gtatatttgg tactgtattt ccctctcatt
1141 ttgacctact ctcatgctgc agagggtact ttaagacata ctccttccat caaatagaac
1201 cactatgaag ctacctcaaa cttccagtca ggtagttgca attgaattaa attaggaata
1261 aataaaaatg gatactggtg cagtcattat gagaggcaat gattgttaat ttacagcttt
1321 catgattagc aagttacagt gatgctgtgc tatgaatttt caagtaattg tgaaaaagtt
1381 aaacattgaa gtaatgaatt tttatgatat tccccccact taagactgtg tattctagtt
1441 ttgtcaaact gtagaaatga tgatgtggaa gaacttaggc atctgtgggc atggtcaaag
1501 gctcaaacct ttattttaga attgatatac acggatgact taactgcatt ttagaccatt
1561 tatctgggat tatggttttg tgatgtttgt cctgaacact tttgttgtaa aaaaataata
1621 ataataatgt ttaatattga gaaagaaact aatattttat gtgagagaaa gtgtgagcaa
1681 actaacttga cttttaaggc taaaacttaa cattcataga ggggtggagt tttaactgta
1741 aggtgctaca atgcccctgg atctaccagc ataaatatct tctgatttgt ccctatgcat
1801 atcagttgag cttcatatac cagcaatata tctgaagagc tattatataa aaaccccaaa
1861 ctgttgatta ttagccaggt aatgtgaata aattctatag gaacatatga aaatacaact
1921 taaataataa acagtggaat ataaggaaag caataaatga atgggctgag ctgcctgtaa
1981 cttgagagta gatggtttga gcctgagcag agacatgact cagcctgttc catgaaggca
2041 gagccatgga ccacgcagga agggcctaca gcccatttct ccatacgcac tggtatgtgt
2101 ggatgatgct gccagggcgc catcgccaag taagaaagtg aagcaaatca gaaacttgtg
2161 aagtggaaat gttctaaagg tggtgaggca ataaaaatca tagtactctt tgtagcaaaa
2221 ttcttaagta tgttattttc tgttgaagtt tacaatcaaa ggaaaatagt aatgttttat
2281 actgtttact gaaagaaaaa gacctatgag cacataggac tctagacggc atccagccgg
2341 aggccagagc tgagcactca gcccgggagg caggctccag gcctcagcag gtgcggagcc
2401 gtcactgcac caagtctcac tggctgtcag tatgacattt cacgggagat ttcttgttgc
2461 tcaaaaaatg agctcgcatt tgtcaatgac agtttctttt ttcttactag acctgtaact
2521 tttgtaaata cacacagcat gtaatggtat cttaaagtgt gtttctatgt gacaattttg
2581 tacaaatttg ttattttcca tttttatttc aaaatataca ttcaaactta aaatt
//