LOCUS HSU12535 3832 bp mRNA linear HUM 18-FEB-1995
DEFINITION Human epidermal growth factor receptor kinase substrate (Eps8)
mRNA, complete cds.
ACCESSION U12535
VERSION U12535.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3832)
AUTHORS Wong,W.T., Carlomagno,F., Druck,T., Barletta,C., Croce,C.M.,
Huebner,K., Kraus,M.H. and Di Fiore,P.P.
TITLE Evolutionary conservation of the EPS8 gene and its mapping to human
chromosome 12q23-q24
JOURNAL Oncogene 9 (10), 3057-3061 (1994)
PUBMED 8084614
REFERENCE 2 (bases 1 to 3832)
AUTHORS Di Fiore,P.
TITLE Direct Submission
JOURNAL Submitted (21-JUL-1994) Pier Paolo Di Fiore, Lab. Cellular &
Molecular Biology, National Cancer Institute, Building 37, Room
1D23, Bethesda, MD 20892, USA
FEATURES Location/Qualifiers
source 1..3832
/db_xref="H-InvDB:HIT000218087"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="12"
/map="12q23-q24"
gene 1..3832
/gene="Eps8"
CDS 210..2678
/gene="Eps8"
/codon_start=1
/product="epidermal growth factor receptor kinase
substrate"
/protein_id="AAA62280.1"
/translation="MNGHISNHPSSFGMYPSQMNGYGSSPTFSQTDREHGSKTSAKAL
YEQRKNYARDSVSSVSDISQYRVEHLTTFVLDRKDAMITVDDGIRKLKLLDAKGKVWT
QDMILQVDDRAVSLIDLESKNELENFPLNTIQHCQAVMHSCSYDSVLALVCKEPTQNK
PDLHLFQCDEVKANLISEDIESAISDSKGGKQKRRPDALRMISNADPSIPPPPRAPAP
APPGTVTQVDVRSRVAAWSAWAADQGDFEKPRQYHEQEETPEMMAARIDRDVQILNHI
LDDIEFFITKLQKAAEAFSELSKRKKNKKGKRKGPGEGVLTLRAKPPPPDEFLDCFQK
FKHGFNLLAKLKSHIQNPSAADLVHFLFTPLNMVVQATGGPELASSVLSPLLNKDTID
FLNYTVNGDERQLWMSLGGTWMKARAEWPKEQFIPPYVPRFRNGWEPPMLNFMGATME
QDLYQLAESVANVAEHQRKQEIKRLSTEHSSVSEYHPADGYAFSSNIYTRGSHLDQGE
AAVAFKPTSNRHIDRNYEPLKTQPKKYAKSKYDFVARNNSELSVLKDDILEILDDRKQ
WWKVRNASGDSGFVPNNILDIVRPPESGLGRADPPYTHTIQKQRMEYGPRPADTPPAP
SPPPTPAPVPVPLPPSTPAPVPVSKVPANITRQNSSSSDSGGSIVRDSQRHKQLPVDR
RKSQMEEVQDELIHRLTIGRSAAQKKFHVPRQNVPVINITYDSTPEDVKTWLQSKGFN
PVTVNSLGVLNGAQLFSLNKDELRTVCPEGARVYSQITVQKAALEDSSGSSELQEIMR
RRQEKISAAASDSGVESFDEGSSH"
BASE COUNT 1171 a 781 c 840 g 1040 t
ORIGIN
1 cgcgaggccg gcgctgtgct cgcctcggag atcgctgctc tttagctggg tgcagaaggc
61 ggctccgcgg ctcgcggacg actggctggg cgcgaatcag attggggggc tttctcccgg
121 tcccctccca cctcgtctgg gctcgcggcg tctccgggga aagccgtggc cccgagggcg
181 gatccgagaa cacacaagtg aaagacacaa tgaatggtca tatttctaat catcccagta
241 gttttggaat gtacccatct cagatgaatg gctacggatc atcacctacc ttttcccaga
301 cggacagaga acatggttca aaaacaagtg caaaggccct ttatgaacaa aggaagaatt
361 atgcacggga cagtgtcagc agtgtgtcag atatatctca ataccgtgtt gaacacttga
421 ctacctttgt cctggatcgg aaagatgcta tgatcactgt tgatgatgga ataaggaaat
481 tgaaattgct tgatgccaag ggcaaagtgt ggactcaaga tatgattctt caagtggatg
541 acagagctgt gagcctgatt gatttagaat caaagaatga actggagaat tttcctttaa
601 acacaatcca gcactgccaa gctgtgatgc attcatgcag ctatgattca gttcttgcac
661 tggtgtgcaa agagccaacc cagaacaagc cagatcttca tctcttccag tgtgatgagg
721 ttaaggcaaa cctaattagt gaagatattg aaagtgcaat cagtgacagt aaaggaggga
781 aacagaagag gcggcccgac gccctgagga tgatttccaa tgcagaccct agtataccgc
841 ctccacccag agctcctgcc cctgcgcccc ctgggaccgt cacccaggtg gatgttagaa
901 gtcgagtggc agcctggtct gcatgggcag ccgaccaagg ggactttgag aaaccaaggc
961 agtatcatga gcaggaagaa acacctgaga tgatggcagc ccgcattgac agagatgtgc
1021 aaatcttaaa ccacattttg gatgacattg aattttttat cacaaaactc caaaaagcag
1081 cagaagcatt ttctgagctt tctaaaagga agaaaaacaa gaaaggtaaa aggaaaggac
1141 caggagaggg tgttttaacg ctgcgggcaa aacctccacc tcctgatgaa tttcttgact
1201 gtttccaaaa gtttaaacac ggatttaacc ttctggccaa actgaagtct catattcaga
1261 atcctagtgc tgcagatttg gttcactttt tgtttactcc attaaatatg gtggtgcagg
1321 caacaggagg tcctgaacta gccagttcag tacttagtcc cctattgaat aaggacacaa
1381 ttgatttctt aaattatact gtcaatggtg atgaacggca gctgtggatg tcattgggag
1441 gaacttggat gaaagccaga gcagagtggc caaaagaaca gtttattcca ccatatgttc
1501 cacgattccg caatggctgg gagcccccaa tgctgaactt tatgggagcc acaatggaac
1561 aagatcttta tcaactggca gaatctgtgg caaatgtagc agaacatcag cgcaaacagg
1621 aaataaaaag attatccaca gagcattcca gtgtatcaga gtatcatcca gccgatggct
1681 atgcgttcag tagcaacatt tacacaagag gatcccacct ggaccaaggg gaagctgctg
1741 ttgcttttaa gccaacttct aatcgccata tagatagaaa ttatgaacca ctcaaaacac
1801 aacccaagaa atatgccaaa tccaagtatg actttgtagc aaggaacaac agtgagctct
1861 cggttctaaa ggatgatatt ttagagatac ttgatgatcg gaagcaatgg tggaaagttc
1921 gaaatgcaag tggagactct ggatttgtgc caaataacat tttggatatt gtgagacctc
1981 cagaatctgg attggggcgt gctgatccac cttatactca tactatacag aaacaaagga
2041 tggagtatgg cccaagacca gctgatactc cccctgctcc atcacctcct ccaacaccag
2101 ctcctgttcc tgttcccctt cccccttcca ctccagcacc tgttcctgtg tcaaaggtcc
2161 cagcaaatat aacacgtcaa aacagcagct ccagtgacag tggtggcagt atcgtgcgag
2221 acagccagag acacaaacaa cttccggtgg accgaaggaa atctcagatg gaggaagtgc
2281 aagatgaact catccacaga ctgaccattg gtcggagtgc cgctcagaag aaattccatg
2341 tgccacggca gaacgtgcca gttatcaata tcacttacga ctccacacca gaggatgtga
2401 agacgtggtt acagtcaaag ggattcaacc ctgtgactgt caatagtctt ggagtattaa
2461 atggtgcaca acttttctct ctcaataagg atgaactgag gacagtctgc cctgaagggg
2521 cgagagtcta tagccaaatc actgtacaaa aagctgcatt ggaggatagc agtggcagct
2581 ccgagttaca agaaattatg agaagacgac aggaaaaaat cagtgctgcc gctagtgatt
2641 caggagtgga atcttttgat gaaggaagca gtcactaatt tgtttgtttg tatttaaact
2701 ccattgtttt tggcattatt ccaacatgct ttgttttaag aagccttgaa gggaatgtca
2761 gattcatttt tcttgatgta atttatcacc ataaaaaaaa aacccatgca aacctgagtg
2821 agcacaggat ttgcttctag gcccattatt tttattaaaa ctgaaaaaat ttaaactgaa
2881 ttttttgacc ttggaaaata tttttcttac tttaccaagg tgaagtttcc ttaattagac
2941 taattatttt atccccatcc cagggtataa acaggaattg ttttgatagt ggtggagtta
3001 ttcactgcaa caaagcaaca atgttgtcca tgattcaaaa tctaagcagt ttcgattttg
3061 cctgtgaata tggtgtctgt cattcagggc atagctcact gtaggctagc ctctgcttac
3121 ttaagtctct tctctgacat actcaatgga agaatattta gatttattta aagttcttaa
3181 tgccaacagt ttaaaaaaaa attaaaacat ttgaatgaac tgtaaagtac agccatacct
3241 tggacatgca aatataaatc tatggagcat tctcaagaca gtttgtcatg gctctgttga
3301 ttgcaactcc ttgtatagct tgtattttga tttagtttat attctgctta ttatgtatac
3361 tgtgttctta tatatgagaa agcacaaatg cgaaagaggt catgtcttct caaaatctag
3421 caaaggaagt agtctgcatt ggtgtgcatt acagtatttt gcttaatgaa agcctcagtt
3481 ctgaatgttg atatgagtag ttaaaaggaa gtggggccat tttatgtgtt tatctgtgtc
3541 aagtatttct ggtaataaga agcacttaat ttacacatat tttaatcctg tgaaagattc
3601 cacatagaga aaagaaagat acctaacctt caacaaatgt tatttttgga aacacaattt
3661 ttgtcattaa atgttatatt atttcacata tataaaacag atgttatgta agaatgttgt
3721 atattttaac ataaatcatt tagagaaatt atctagattc attaattttc atagtgcctt
3781 tttcacatga gtcagctgga aagtctgcaa taaacagtat ttgctgtctg tt
//