LOCUS HSU09623 1966 bp mRNA linear HUM 30-NOV-1995
DEFINITION Human alcohol dehydrogenase (ADH7) mRNA, complete cds.
ACCESSION U09623
VERSION U09623.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1966)
AUTHORS Kedishvili,N.Y., Bosron,W.F., Stone,C.L., Hurley,T.D., Peggs,C.F.,
Thomasson,H.R., Popov,K.M., Carr,L.G., Edenberg,H.J. and Li,T.K.
TITLE Expression and kinetic characterization of recombinant human
stomach alcohol dehydrogenase. Active-site amino acid sequence
explains substrate specificity compared with liver isozymes
JOURNAL J. Biol. Chem. 270 (8), 3625-3630 (1995)
PUBMED 7876099
REFERENCE 2 (bases 1 to 1966)
AUTHORS Kedishvili,N.Y.
TITLE Direct Submission
JOURNAL Submitted (11-MAY-1994) Natalia Y. Kedishvili, Indiana University,
Biochemistry and Molecular Biology, 635 Barnhill Dr., Indianapolis,
IN 46202-5122, USA
FEATURES Location/Qualifiers
source 1..1966
/db_xref="H-InvDB:HIT000217929"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="stomach"
/clone_lib="human stomach lambda gt11 cDNA library"
/dev_stage="adult"
gene 1..1966
/gene="ADH7"
5'UTR 1..18
/gene="ADH7"
CDS 19..1143
/gene="ADH7"
/EC_number="1.1.1.1"
/function="alcohol oxidation"
/experiment="experimental evidence, no additional details
recorded"
/citation=[1]
/codon_start=1
/product="alcohol dehydrogenase"
/protein_id="AAA82165.1"
/translation="MGTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILAT
GICRTDDHVIKGTMVSKFPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECN
ACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKI
DDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASR
IIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMI
DALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTE
FLAKKFDLDQLITHVLPFKKISEGFELLNSGQSIRTVLTF"
3'UTR 1144..1966
/gene="ADH7"
BASE COUNT 608 a 355 c 425 g 578 t
ORIGIN
1 cgggactttt tctgactgat gggcactgct ggaaaagtta ttaaatgcaa agcagctgtg
61 ctttgggagc agaagcaacc cttctccatt gaggaaatag aagttgcccc accaaagact
121 aaagaagttc gcattaagat tttggccaca ggaatctgtc gcacagatga ccatgtgata
181 aaaggaacaa tggtgtccaa gtttccagtg attgtgggac atgaggcaac tgggattgta
241 gagagcattg gagaaggagt gactacagtg aaaccaggtg acaaagtcat ccctctcttt
301 ctgccacaat gtagagaatg caatgcttgt cgcaacccag atggcaacct ttgcattagg
361 agcgatatta ctggtcgtgg agtactggct gatggcacca ccagatttac atgcaagggc
421 aaaccagtac accacttcat gaacaccagt acatttaccg agtacacagt ggtggatgaa
481 tcttctgttg ctaagattga tgatgcagct cctcctgaga aagtctgttt aattggctgt
541 gggttttcca ctggatatgg cgctgctgtt aaaactggca aggtcaaacc tggttccact
601 tgcgtcgtct ttggcctggg aggagttggc ctgtcagtca tcatgggctg taagtcagct
661 ggtgcatcta ggatcattgg gattgacctc aacaaagaca aatttgagaa ggccatggct
721 gtaggtgcca ctgagtgtat cagtcccaag gactctacca aacccatcag tgaggtgctg
781 tcagaaatga caggcaacaa cgtgggatac acctttgaag ttattgggca tcttgaaacc
841 atgattgatg ccctggcatc ctgccacatg aactatggga ccagcgtggt tgtaggagtt
901 cctccatcag ccaagatgct cacctatgac ccgatgttgc tcttcactgg acgcacatgg
961 aagggatgtg tctttggagg tttgaaaagc agagatgatg tcccaaaact agtgactgag
1021 ttcctggcaa agaaatttga cctggaccag ttgataactc atgttttacc atttaaaaaa
1081 atcagtgaag gatttgagct gctcaattca ggacaaagca ttcgaacggt cctgacgttt
1141 tgagatccaa agtggcagga ggtctgtgtt gtcatggtga actggagttt ctcttgtgag
1201 agttccctca tctgaaatca tgtatctgtc tcacaaatac aagcataagt agaagatttg
1261 ttgaagacat agaaccctta taaagaatta ttaaccttta taaacattta aagtcttgtg
1321 agcacctggg aattagtata ataacaatgt taatattttt gatttacatt ttgtaaggct
1381 ataattgtat cttttaagaa aacatacact tggatttcta tgttgaaatg gagattttta
1441 agagttttaa ccagctgctg cagatatata actcaaaaca gatatagcgt ataaagatat
1501 agtaaatgca tctcccagag taatattcac ttaacacatt gaaactatta ttttttagat
1561 ttgaatataa atgtattttt taaacacttg ttatgagtta acttggatta cattttgaaa
1621 tcagttcatt ccatgatgca tattactgga ttagattaag aaagacagaa aagattaagg
1681 gacgggcaca tttttcaacg attaagaatc atcattacat aacttggtga aactgaaaaa
1741 gtatatcata tgggtacaca aggctatttg ccagcatata ttaatatttt agaaaatatt
1801 ccttttgtaa tactgaatat aaacatagag ctagagtcat attatcatac ttatcataat
1861 gttcaatttg atacagtaga attgcaagtc cctaagtccc tattcactgt gcttagtagt
1921 gactccattt aataaaaagt gtttttagtt tttaacaact aaaccg
//