LOCUS HSU09564 4326 bp mRNA linear HUM 05-AUG-1994
DEFINITION Human serine kinase mRNA, complete cds.
ACCESSION U09564
VERSION U09564.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4326)
AUTHORS Gui,J.F., Lane,W.S. and Fu,X.D.
TITLE A serine kinase regulates intracellular localization of splicing
factors in the cell cycle
JOURNAL Nature 369 (6482), 678-682 (1994)
PUBMED 8208298
REFERENCE 2 (bases 1 to 4326)
AUTHORS Fu,X.
TITLE Direct Submission
JOURNAL Submitted (10-MAY-1994) Xiang-Dong Fu, Cellular and Molecular
Medicine, University of California San Diego, 9500 Gilman Drive, La
Jolla, CA 92093, USA
FEATURES Location/Qualifiers
source 1..4326
/db_xref="H-InvDB:HIT000217919"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="pSK-SRPK1"
/cell_line="HeLa S3"
/clone_lib="Uni-Zap XR HeLa S3"
CDS 109..2076
/function="serine kinase for SR splicing factors"
/codon_start=1
/product="serine kinase"
/protein_id="AAA20530.1"
/translation="MERKVLALQARKKRTKAKKDKAQRKSETQHRGSAPHSESDLPEQ
EEEILGSDDDEQEDPNDYCKGGYHLVKIGDLFNGRYHVIRKLGWGHFSTVWLSWDIQG
KKFVAMKVVKSAEHYTETALDEIRLLKSVRNSDPNDPNREMVVQLLDDFKISGVNGTH
ICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPEN
ILLSVNEQYIRRLAAEATEWQRSGAPPPSGSAVSTAPQPKPADKMSKNKKKKLKKKQK
RQAELLEKRMQEIEEMEKESGPGQKRPNKQEESESPVERPLKENPPNKMTQEKLEESS
TIGQDQTLMERDTEGGAAEINCNGVIEVINYTQNSNNETLRHKEDLHNANDCDVQNLN
QESSFLSLPNGDSSTSQETDSCTPITSEVSDTMVCQSSSTVGQSFSEQHISQLQESIR
AEIPCEDEQEQEHNGPLDNKGKSTAGNFLVNPLEPKNAEKLKVKIADLGNACWVHKHF
TEDIQTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYLFEPHSGEEYTRDEDHI
ALIIELLGKVPRKLIVAGKYSKEFFTKKGDLKHITKLKPWGLFEVLVEKYEWSQEEAA
GFTDFLLPMLELIPEKRATAAECLRHPWLNS"
regulatory 4202..4207
/regulatory_class="polyA_signal_sequence"
/inference="non-experimental evidence, no additional
details recorded"
polyA_site 4326
/note="20 A residues"
BASE COUNT 1296 a 867 c 894 g 1269 t
ORIGIN
1 atataaaata gtattccaaa taagtacatt ttatagcaaa attatgcatt tttcctaaga
61 ctttcatcac caatatcgcc ttataccctg cttttgttgg gtctcaccat ggagcggaaa
121 gtgcttgcgc tccaggcccg aaagaaaagg accaaggcca agaaggacaa agcccaaagg
181 aaatctgaaa ctcagcaccg aggctctgct ccccactctg agagtgatct accagagcag
241 gaagaggaga ttctgggatc tgatgatgat gagcaagaag atcctaatga ttattgtaaa
301 ggaggttatc atcttgtgaa aattggagat ctattcaatg ggagatacca tgtgatccga
361 aagttaggct ggggacactt ttcaacagta tggttatcat gggatattca ggggaagaaa
421 tttgtggcaa tgaaagtagt taaaagtgct gaacattaca ctgaaacagc actagatgaa
481 atccggttgc tgaagtcagt tcgcaattca gaccctaatg atccaaatag agaaatggtt
541 gttcaactac tagatgactt taaaatatca ggagttaatg gaacacatat ctgcatggta
601 tttgaagttt tggggcatca tctgctcaag tggatcatca aatccaatta tcaggggctt
661 ccactgcctt gtgtcaaaaa aattattcag caagtgttac agggtcttga ttatttacat
721 accaagtgcc gtatcatcca cactgacatt aaaccagaga acatcttatt gtcagtgaat
781 gagcagtaca ttcggaggct ggctgcagaa gcaacagaat ggcagcgatc tggagctcct
841 ccgccttccg gatctgcagt cagtactgct ccccagccta aaccagctga caaaatgtca
901 aagaataaga agaagaaatt gaagaagaag cagaagcgcc aggcagaatt actagagaag
961 cgaatgcagg aaattgagga aatggagaaa gagtcgggcc ctgggcaaaa aagaccaaac
1021 aagcaagaag aatcagagag tcctgttgaa agacccttga aagagaaccc acctaataaa
1081 atgacccaag aaaaacttga agagtcaagt accattggcc aggatcaaac gcttatggaa
1141 cgtgatacag agggtggtgc agcagaaatt aattgcaatg gagtgattga agtcattaat
1201 tatactcaga acagtaataa tgaaacattg agacataaag aggatctaca taatgctaat
1261 gactgtgatg tccaaaattt gaatcaggaa tctagtttcc taagtctccc aaatggagac
1321 agcagcacat ctcaagaaac agactcttgt acacctataa catctgaggt gtcagacacc
1381 atggtgtgcc agtcttcctc aactgtaggt cagtcattca gtgaacaaca cattagccaa
1441 cttcaagaaa gcattcgggc agagataccc tgtgaagatg aacaagagca agaacataac
1501 ggaccactgg acaacaaagg aaaatccacg gctggaaatt ttcttgttaa tccccttgag
1561 ccaaaaaatg cagaaaagct caaggtgaag attgctgacc ttggaaatgc ttgttgggtg
1621 cacaaacatt tcactgaaga tattcaaaca aggcaatatc gttccttgga agttctaatc
1681 ggatctggct ataatacccc tgctgacatt tggagcacgg catgcatggc ctttgaactg
1741 gccacaggtg actatttgtt tgaacctcat tcaggggaag agtacactcg agatgaagat
1801 cacattgcat tgatcataga acttctgggg aaggtgcctc gcaagctcat tgtggcagga
1861 aaatattcca aggaattttt caccaaaaaa ggtgacctga aacatatcac gaagctgaaa
1921 ccttggggcc tttttgaggt tctagtggag aagtatgagt ggtctcagga agaggcagct
1981 ggcttcacag atttcttact gcccatgttg gagctgatcc ctgagaagag agccactgcc
2041 gccgagtgtc tccggcaccc ttggcttaac tcctaagccc ctgcccagca ccacagcaga
2101 gatcacacac tgaccctccg cccttcccct tcaagcattt tcctcttccc ttttcagggt
2161 gaagctcttc cttcaagagt ttctagatct tgtttttttt ttaatccaac atgttcattt
2221 gggtttgctt acttgaccct gtggagatcc ccacagccat tgggcatcct aggtgaattt
2281 ggccttggtt ggctctgcca aagactaatg gactaaaatg tgaaacagcc tcttgccctg
2341 tacctttcct tcccattagg acatccttta aattataagc atcctttttg aaaagagcta
2401 tgaaggtgta tgagcccatc cttttattca ttgactctaa gagtcaaatt ttctagtgca
2461 tatcctattg ccagcataag gatgaggagg gggaaagggt cttaattcta tgtacagcag
2521 agacattaaa cttgctgtgt ccgggctgca tcatcttcct ggactgtttc tgttgttctc
2581 tgtgttcaca ttttttcctg caacttttaa gctactgtct tttttaaata gctatatgaa
2641 caccaaattt gggtaccatt ttatcactgt tcaaagcact gtcaaattcc tttcatcctt
2701 taatagttaa gatctttgaa tcttcagtct gatttttaat gtaagcaaaa acagaaccat
2761 tgaatagtaa tttcttgaga acctcaggtg ttctataaac agtcctttcc tgtatgtctt
2821 ctattaccct aagaccagag ttattttggt tggttgtttt gttttatttt ttgtttttgt
2881 atccatggct ggcactttac tcattgcact tgagtttatt gccccataac taaaggatca
2941 ggatgatggt agaacggaga tctgggtttc agagctttcc catttaagaa aaatagatct
3001 tgagattctg attcttttcc aaacagtccc ctgctttcat gtacagcttt ttctttacct
3061 tacccaaaat tctggccttg aagcagtttt cctctatggc tttgctttct gattttctca
3121 gaggctcgag tctttaatat aaccccaaat gaaagaacca aggggagggg tgggatggca
3181 cttttttttg ttggtcttgt tttgttttgt tttttggttg gttggttatt ttttaagatt
3241 agccattctc tgctgctatt tccctacata atgtcaattt ttaaccataa ttttgacatg
3301 attgagatgt acttgaggct tttttgtttt aattgagaaa agactttgca attttttttt
3361 aggatgagcc tctcctagac ttgacctaga atattacata ttcctccagt aatactgaag
3421 agcaaaagag aggcaggatt ggggtcacag ccgcttcttc agcatggacc aagtgggcct
3481 tggggattgc agcgttctcg aagtggctgt aggactcgaa tttacagaaa gccacagagg
3541 tgcaacttga ggctctgcta gcaagccacc agtgaggcta ttgggtaacc acctttctat
3601 acaggagatt ggaatctact ttgtcattta tccaccacag tgacaaagga aaagtggtgc
3661 cgttatgcaa tccatttaac tcataaacat attactctga gtaactggcc agccattcat
3721 cggatccttc attgggtact cctgaaatca gacatgttcc tgtagaaaga attttaagtt
3781 aggctttcta tgcacctatc aagaatcaag agaatagatt gtatcaaaca acggcaggga
3841 aatccttcag caattctaat ccactttggg ttttcagctg tttttacatc taaagcaata
3901 gactagaact gaattatctt ctacatagta aaatcacaat tgtggaattc tggtgatatt
3961 aaggtgaaat aacaaaacac aaaaggccct attttaacag ttgatgtgac agtaagtttt
4021 aatagaacct gtaacttcat tttggaaatg cttctccacc aaataagggc tttttcccct
4081 atttaaggag ccagatggat tgaaagatgt ggaaataggc agctgtagat cttgatcttc
4141 caggtacccc atgtaccttt attgagctta attataatac tgtcaaattg ccacgatctc
4201 actaaaggat ttctatttgc tgtcagttaa aaataaagcc ctaaatacat ttttattctt
4261 tctactgagg gcattgtctg ttttctttgt aaatgccgta caataaacaa attatttaat
4321 aaccta
//