LOCUS HSU09303 2895 bp mRNA linear HUM 23-JAN-1997
DEFINITION Human T cell leukemia LERK-2 (EPLG2) mRNA, complete cds.
ACCESSION U09303
VERSION U09303.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2895)
AUTHORS Fletcher,F.A., Huebner,K., Shaffer,L.G., Monaco,A., Mueller,U.,
Kozlosky,C., Druck,T., Simoneaux,D.K., Fairweather,N., Chelly,J.,
Cerretti,D.P., Belmont,J.W., Beckmann,M.P. and Lyman,S.D.
TITLE Assignment of the human Elk ligand gene, EPLG2, to chromosome
region Xq12
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 2895)
AUTHORS Fletcher,F.A.
TITLE Direct Submission
JOURNAL Submitted (29-APR-1994) Frederick A. Fletcher, Dept. Molecular
Immunology, Immunex Research and Development Corp., 51 University
St., Seattle, WA 98101, USA
FEATURES Location/Qualifiers
source 1..2895
/db_xref="H-InvDB:HIT000217899"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="X"
/map="Xq12"
/cell_line="CCRF-HSB2 (ATCC CCL 120.1)"
/cell_type="T cell leukemia"
gene 1..2895
/gene="EPLG2"
CDS 702..1742
/gene="EPLG2"
/function="tyrosine kinase receptor"
/standard_name="ligand for EPH related kinase"
/note="EPH ligand"
/codon_start=1
/product="LERK-2"
/protein_id="AAB41127.1"
/translation="MARPGQRWLGKWLVAMVVWALCRLATPLAKNLEPVSWSSLNPKF
LSGKGLVIYPKIGDKLDIICPRAEAGRPYEYYKLYLVRPEQAAACSTVLDPNVLVTCN
RPEQEIRFTIKFQEFSPNYMGLEFKKHHDYYITSTSNGSLEGLENREGGVCRTRTMKI
IMKVGQDPNAVTPEQLTTSRPSKEADNTVKMATQAPGSRGSLGDSDGKHETVNQEEKS
GPGASGGSSGDPDGFFNSKVALFAAVGAGCVIFLLIIIFLTVLLLKLRKRHRKHTQQR
AAALSLSTLASPKGGSGTAGTEPSDIIIPLRTTENNYCPHYEKVSGDYGHPVYIVQEM
PPQSPANIYYKV"
repeat_region 2443..2476
/gene="EPLG2"
/rpt_unit_seq="ca"
BASE COUNT 563 a 888 c 900 g 544 t
ORIGIN
1 cgggctcgat cgcccgggag ccaggactcg gcgacgcgag gctgccgggc tacccggccg
61 aggcttcggg ggcgcaaact aatgggactg gctcgctcgg cagcatctcc ccgctcttct
121 aagtacactg agcagggccc gcgctgaagt agaagctgtc cgggggcgcg tagcccggag
181 tcccagtgtg gcccggagga acggagcccg tgccagggcg gcccagtcgg gagcccgggg
241 accgagcttg tgctgtgggg aaacccccac ttcttccaag ggacagcgat cccgggacgg
301 tcgaggcgtc ggggcggtca ccgagacctc tgcgggaaga ccccgtcggg gagagggcgc
361 gcagccccga agcgtctcgg gaagtcgagc ggaatcgggc gggatcaccc gggggcgcag
421 agcccccgtc gcgcctcgtg cggcagcgga gagcccagga gaacgagccc tcgggggccg
481 aagcccatgc ccgggttggg ggcggctgcc cagtgagtcc tcctggccgg ccgggcggag
541 aagagcgaca ccgaagccgg cgggagggga gcacttcaag gccggcggct gcggaggatg
601 ggcgcctgag cggctccgag cgcagcgcgg cagaggaagg cgaggcgagc tttggtgagg
661 aggcgccaag ggatcccgaa gtgcagtctg cccccgggaa gatggctcgg cctgggcagc
721 gttggctcgg caagtggctt gtggcgatgg tcgtgtgggc gctgtgccgg ctcgccacac
781 cgctggccaa gaacctggag cccgtatcct ggagctccct caaccccaag ttcctgagtg
841 ggaagggctt ggtgatctat ccgaaaattg gagacaagct ggacatcatc tgcccccgag
901 cagaagcagg gcggccctat gagtactaca agctgtacct ggtgcggcct gagcaggcag
961 ctgcctgtag cacagttctc gaccccaacg tgttggtcac ctgcaatagg ccagagcagg
1021 aaatacgctt taccatcaag ttccaggagt tcagccccaa ctacatgggc ctggagttca
1081 agaagcacca tgattactac attacctcaa catccaatgg aagcctggag gggctggaaa
1141 accgggaggg cggtgtgtgc cgcacacgca ccatgaagat catcatgaag gttgggcaag
1201 atcccaatgc tgtgacgcct gagcagctga ctaccagcag gcccagcaag gaggcagaca
1261 acactgtcaa gatggccaca caggcccctg gtagtcgggg ctccctgggt gactctgatg
1321 gcaagcatga gactgtgaac caggaagaga agagtggccc aggtgcaagt gggggcagca
1381 gcggggaccc tgatggcttc ttcaactcca aggtggcatt gttcgcggct gtcggtgccg
1441 gttgcgtcat cttcctgctc atcatcatct tcctgacggt cctactactg aagctacgca
1501 agcggcaccg caagcacaca cagcagcggg cggctgccct ctcgctcagt accctggcca
1561 gtcccaaggg gggcagtggc acagcgggca ccgagcccag cgacatcatc attcccttac
1621 ggactacaga gaacaactac tgcccccact atgagaaggt gagtggggac tacgggcacc
1681 ctgtctacat cgtccaagag atgccgcccc agagcccggc gaacatctac tacaaggtct
1741 gagtgcccgg cacggcctca ggccccaggg acagtcggcc tggaccggac ctctcctttc
1801 gcccccacac cccctcccct tgccagctgt gcccaccttt gtatttagtt ttgtagtttc
1861 ttggctttta taatccccct ttttccctgc cccctgggct tcggaggggg gtgcttgtgc
1921 ccctaacccc catgctcttg tgccttcccc ctctggccag gcctctgggc tccgtggggg
1981 cgccccttct tggaaggcag ggctggacac tgatggacag caggcaggga gacagtcccc
2041 tggtcctgcc cctccctcgc cccccttgcc accttcccag gactgcttgt ccgctatcat
2101 cactgttttt aatgcttttg tgttcatttt ttagctgtca actcattttc atctgttttt
2161 tgaagaaaaa tggaaaaatg taaaaggcag cccctcccca ggctttgtga gcctggccca
2221 agccagtaca agagggcctg gggcacgatg tggtcagcca ggaagcatag gatgccattt
2281 cttttataga ttccttggta tttctggtgg ggtaaggggc aggccagggc tgttcacgcc
2341 catgagggaa gaggaaagtg ccactgggca aggtgtccca ccctcccctc ctgaccctcc
2401 tacgaggctt atcctggcaa tggggtagtc actgccaccc ttccacacac acacacacac
2461 acacacacac acacacaaaa atcccttcct tgtgggattc ttgggcatct cctgcctccc
2521 tcactctcac ggtaattaat gtcttaattg gctgttgcct ggggaacagg agagctgctg
2581 caggcagatg acctcatggg gggtggaggg aggtgaggtg cccaggtgtc tatttaccct
2641 gcagagctgg gagtttcacc ccacccccca ccctgttctc tccttacctt tggcatcctt
2701 tggcctggtg gggaaacaga ggcccagggt ggagacctaa gcgggtataa gaccaggtgg
2761 cctgctcctt ttctgggccc tagcacaggt gggtaacccc cacccaaccc agctcctgct
2821 gctgtcccag tcttgggctg ggccctggaa agaggaagag cctgcctggg agcaggtcgt
2881 ctcgttccaa gatct
//