LOCUS HSU08854 2090 bp mRNA linear HUM 01-FEB-1995
DEFINITION Human UDP glucuronosyltransferase precursor (UGT2B15) mRNA,
complete cds.
ACCESSION U08854
VERSION U08854.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2090)
AUTHORS Green,M.D., Oturu,E.M. and Tephly,T.R.
TITLE Stable expression of a human liver UDP-glucuronosyltransferase
(UGT2B15) with activity toward steroid and xenobiotic substrates
JOURNAL Drug Metab. Dispos. 22 (5), 799-805 (1994)
PUBMED 7835232
REFERENCE 2 (bases 1 to 2090)
AUTHORS Green,M.D.
TITLE Direct Submission
JOURNAL Submitted (13-APR-1994) Mitchell D. Green, Department of
Pharmacology, The University of Iowa, Iowa City, IA 52242, USA
FEATURES Location/Qualifiers
source 1..2090
/db_xref="H-InvDB:HIT000217848_04"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="HE8a"
/tissue_type="liver"
/clone_lib="Human liver UniZap cDNA library from
Stratagene"
gene 1..2090
/gene="UGT2B15"
CDS 22..1614
/gene="UGT2B15"
/EC_number="2.4.1.17"
/codon_start=1
/product="UDP glucuronosyltransferase precursor"
/protein_id="AAC50077.1"
/translation="MSLKWTSVFLLIQLSCYFSSGSCGKVLVWPTEYSHWINMKTILE
ELVQRGHEVTVLTSSASTLVNASKSSAIKLEVYPTSLTKNDLEDSLLKILDRWIYGVS
KNTFWSYFSQLQELCWEYYDYSNKLCKDAVLNKKLMMKLQESKFDVILADALNPCGEL
LAELFNIPFLYSLRFSVGYTFEKNGGGFLFPPSYVPVVMSELSDQMIFMERIKNMIHM
LYFDFWFQIYDLKKWDQFYSEVLGRPTTLFETMGKAEMWLIRTYWDFEFPRPFLPNVD
FVGGLHCKPAKPLPKEMEEFVQSSGENGIVVFSLGSMISNMSEESANMIASALAQIPQ
KVLWRFDGKKPNTLGSNTRLYKWLPQNDLLGHPKTKAFITHGGTNGIYEAIYHGIPMV
GIPLFADQHDNIAHMKAKGAALSVDIRTMSSRDLLNALKSVINDPVYKENVMKLSRIH
HDQPMKPLDRAVFWIEFVMRHKGAKHLRVAAHNLTWIQYHSLDVIAFLLACVATVIFI
ITKFCLFCFRKLAKTGKKKKRD"
sig_peptide 22..90
/gene="UGT2B15"
mat_peptide 91..1611
/gene="UGT2B15"
/product="UDP glucuronosyltransferase"
/EC_number="2.4.1.17"
BASE COUNT 649 a 384 c 435 g 622 t
ORIGIN
1 ttcggcacga gtaagaccag gatgtctctg aaatggacgt cagtctttct gctgatacag
61 ctcagttgtt actttagctc tggaagctgt ggaaaggtgc tagtgtggcc cacagaatac
121 agccattgga taaatatgaa gacaatcctg gaagagcttg ttcagagggg tcatgaggtg
181 actgtgttga catcttcggc ttctactctt gtcaatgcca gtaaatcatc tgctattaaa
241 ttagaagttt atcctacatc tttaactaaa aatgatttgg aagattctct tctgaaaatt
301 ctcgatagat ggatatatgg tgtttcaaaa aatacatttt ggtcatattt ttcacaatta
361 caagaattgt gttgggaata ttatgactac agtaacaagc tctgtaaaga tgcagttttg
421 aataagaaac ttatgatgaa actacaagag tcaaagtttg atgtcattct ggcagatgcc
481 cttaatccct gtggtgagct actggctgaa ctatttaaca taccctttct gtacagtctt
541 cgattctctg ttggctacac atttgagaag aatggtggag gatttctgtt ccctccttcc
601 tatgtacctg ttgttatgtc agaattaagt gatcaaatga ttttcatgga gaggataaaa
661 aatatgatac atatgcttta ttttgacttt tggtttcaaa tttatgatct gaagaagtgg
721 gaccagtttt atagtgaagt tctaggaaga cccactacat tatttgagac aatggggaaa
781 gctgaaatgt ggctcattcg aacctattgg gattttgaat ttcctcgccc attcttacca
841 aatgttgatt ttgttggagg acttcactgt aaaccagcca aacccctgcc taaggaaatg
901 gaagagtttg tgcagagctc tggagaaaat ggtattgtgg tgttttctct ggggtcgatg
961 atcagtaaca tgtcagaaga aagtgccaac atgattgcat cagcccttgc ccagatccca
1021 caaaaggttc tatggagatt tgatggcaag aagccaaata cattaggttc caatactcga
1081 ctgtacaagt ggttacccca gaatgacctt cttggtcatc ccaaaaccaa agcttttata
1141 actcatggtg gaaccaatgg catctatgag gcgatctacc atgggatccc tatggtgggc
1201 attcccttgt ttgcggatca acatgataac attgctcaca tgaaagccaa gggagcagcc
1261 ctcagtgtgg acatcaggac catgtcaagt agagatttgc tcaatgcatt gaagtcagtc
1321 attaatgacc ctgtctataa agagaatgtc atgaaattat caagaattca tcatgaccaa
1381 ccaatgaagc ccctggatcg agcagtcttc tggattgagt ttgtcatgcg ccacaaagga
1441 gccaagcacc ttcgagtcgc agctcacaac ctcacctgga tccagtacca ctctttggat
1501 gtgatagcat tcctgctggc ctgcgtggca actgtgatat ttatcatcac aaaattttgc
1561 ctgttttgtt tccgaaagct tgccaaaaca ggaaagaaga agaaaagaga ttagttatat
1621 caaaagcctg aagtggaatg actgaaagat gggactcctc ctttatttca gcatggaggg
1681 ttttaaatgg aggatttcct ttttcctgtg acaaaacatc ttttcacaac ttaccttgtt
1741 aagacaaaat ttattttcca gggatttaat acgtacttta gttggaatta ttctatgtca
1801 atgattttta agctatgaaa aatacaatgg ggggaaggat agcatttgga gatataccta
1861 atgttaaatg acgagttact ggatgcagca cgcaacatgg cacatgtgta tacatatgta
1921 gctaaccctt cgttgtgcac atgtacccta aaacttaaag tataatttaa aaaaagcaaa
1981 aaaaaaaaat accaactctt ttttttaaac caggaaggaa aatgtgaaca tggaaacaac
2041 ttctagtatt ggatctgaaa ataaagtgtc atccaagcca taaaaaaaaa
//