LOCUS HSU08839 1608 bp mRNA linear HUM 30-JUL-1994
DEFINITION Human urokinase-type plasminogen activator receptor mRNA, complete
cds.
ACCESSION U08839
VERSION U08839.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (sites)
AUTHORS Casey,J.R., Petranka,J.G., Kottra,J., Fleenor,D.E. and Rosse,W.F.
TITLE The Structure of the Urokinase-Type Plasminogen Activator Receptor
Gene
JOURNAL Unpublished
REFERENCE 2 (bases 381 to 1608)
AUTHORS Roldan,A.L., Cubellis,M.V., Masucci,M.T., Behrendt,N., Lund,L.R.,
Dano,K., Appella,E. and Blasi,F.
TITLE Cloning and expression of the receptor for human urokinase
plasminogen activator, a central molecule in cell surface, plasmin
dependent proteolysis
JOURNAL EMBO J. 9 (2), 467-474 (1990)
PUBMED 1689240
REFERENCE 3 (bases 1 to 1608)
AUTHORS Petranka,J.,G.
TITLE Direct Submission
JOURNAL Submitted (13-APR-1994) Petranka J. G., Duke University Medical
Center, Hematology, South Hospital, Durham, NC 27710, USA
FEATURES Location/Qualifiers
source 1..1608
/db_xref="H-InvDB:HIT000217846"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/sex="female"
/cell_line="HeLa"
/clone_lib="cDNA library"
misc_feature 381..1608
/note="sequence previously reported in GenBank Accession
Number X51675"
CDS 427..1299
/codon_start=1
/product="urokinase-type plasminogen activator receptor"
/protein_id="AAB60333.1"
/translation="MGHPPLLPLLLLLHTCVPASWGLRCMQCKTNGDCRVEECALGQD
LCRTTIVRLWEEGEELELVEKSCTHSEKTNRTLSYRTGLKITSLTEVVCGLDLCNQGN
SGRAVTYSRSRYLECISCGSSDMSCERGRHQSLQCRSPEEQCLDVVTHWIQEGEEVLE
LENLPQNGRQCYSCKGNSTHGCSSEETFLIDCRGPMNQCLVATGTHEPKNQSYMVRGC
ATASMCQHAHLGDAFSMNHIDVSCCTKSGCNHPDLDVQYRSGAAPQPGPAHLSLTITL
LMTARLWGGTLLWT"
misc_difference 898^899
/note="exon 5 from a previously sequenced receptor mRNA,
which is spliced out from between nt 898/899 in the
current sequence"
/citation=[2]
/replace="ggcgtccaaaggatgaccgcca
cctccgtggctgtggctaccttcccggctgcccgggctcc
aatggtttccacaacaacgacaccttccacttcctgaaat
gctgcaacaccaccaaatgcaacgagggcccaa"
BASE COUNT 371 a 452 c 443 g 342 t
ORIGIN
1 cagtatccct cctgacaaaa ctaacaaaaa tcctgttagc caaataatca gccacattca
61 tatttaccgt caaagttttt atcctcattt tacagcagtg gagagcgatt gccccgggtc
121 ccacgttagg aagagagaga actgggattt gcacccaggc aatctgggga cagagctgtg
181 atcacaactc catgagtcag ggccgagcca gccccttcac caccagccgg ccgcgccccg
241 ggaaggaagt ttgtggcgga ggaggttcgt acgggaggag ggggaggcgc ccacgcatct
301 ggggctgact cgctctttcg caaaacgtct gggaggagtc cctggggcca caaaactgcc
361 tccttcctga ggccagaagg agagaagacg tgcagggacc ccgcgcacag gagctgccct
421 cgcgacatgg gtcacccgcc gctgctgccg ctgctgctgc tgctccacac ctgcgtccca
481 gcctcttggg gcctgcggtg catgcagtgt aagaccaacg gggattgccg tgtggaagag
541 tgcgccctgg gacaggacct ctgcaggacc acgatcgtgc gcttgtggga agaaggagaa
601 gagctggagc tggtggagaa aagctgtacc cactcagaga agaccaacag gaccctgagc
661 tatcggactg gcttgaagat caccagcctt accgaggttg tgtgtgggtt agacttgtgc
721 aaccagggca actctggccg ggctgtcacc tattcccgaa gccgttacct cgaatgcatt
781 tcctgtggct catcagacat gagctgtgag aggggccggc accagagcct gcagtgccgc
841 agccctgaag aacagtgcct ggatgtggtg acccactgga tccaggaagg tgaagaagtc
901 ctggagcttg aaaatctgcc gcagaatggc cgccagtgtt acagctgcaa ggggaacagc
961 acccatggat gctcctctga agagactttc ctcattgact gccgaggccc catgaatcaa
1021 tgtctggtag ccaccggcac tcacgaaccg aaaaaccaaa gctatatggt aagaggctgt
1081 gcaaccgcct caatgtgcca acatgcccac ctgggtgacg ccttcagcat gaaccacatt
1141 gatgtctcct gctgtactaa aagtggctgt aaccacccag acctggatgt ccagtaccgc
1201 agtggggctg ctcctcagcc tggccctgcc catctcagcc tcaccatcac cctgctaatg
1261 actgccagac tgtggggagg cactctcctc tggacctaaa cctgaaatcc ccctctctgc
1321 cctggctgga tccgggggac ccctttgccc ttccctcggc tcccagccct acagacttgc
1381 tgtgtgacct caggccagtg tgccgacctc tctgggcctc agttttccca gctatgaaaa
1441 cagctatctc acaaagttgt gtgaagcaga agagaaaagc tggaggaagg ccgtgggcaa
1501 tgggagagct cttgttatta ttaatattgt tgccgctgtt gtgttgttgt tattaattaa
1561 tattcatatt atttatttta tacttacata aagattttgt accagtgg
//