LOCUS HSU08316 2260 bp mRNA linear HUM 29-NOV-1995
DEFINITION Human insulin-stimulated protein kinase 1 (ISPK-1) mRNA, complete
cds.
ACCESSION U08316
VERSION U08316.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2260)
AUTHORS Bjorbaek,C., Vik,T.A., Echwald,S.M., Webb,G.C., Wang,J.P.,
Yang,P.Y., Vestergaard,H., Richmond,K., Hansen,T., Erikson,R.L.,
Gabor-Miklos,G.L., Cohen,P.T. and Pedersen,O.
TITLE Cloning of a human insulin-stimulated protein kinase (ISPK-1) gene
and analysis of coding regions and mRNA levels of the ISPK-1 and
the protein phosphatase-1 genes in muscle from NIDDM patients
JOURNAL Diabetes 44 (1), 90-97 (1995)
PUBMED 7813820
REFERENCE 2 (bases 1 to 2260)
AUTHORS Vik,T.A.
TITLE Direct Submission
JOURNAL Submitted (04-APR-1994) Terry A. Vik, Pediatrics, Indiana
University School of Medicine, Riley Hospital for Children, 702
Barnhill Drive, Indianapolis, IN 46202, USA
FEATURES Location/Qualifiers
source 1..2260
/db_xref="H-InvDB:HIT000217835"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="X"
/map="Xp21.3-22.1"
/clone_lib="MOLT 4 T-cell leukemia and human placenta cDNA
libraries"
gene 1..2260
/gene="ISPK-1"
CDS 1..2223
/gene="ISPK-1"
/note="ribosomal protein S6 kinase"
/codon_start=1
/product="insulin-stimulated protein kinase 1"
/protein_id="AAA81952.1"
/translation="MPLAQLADPWQKMAVESPSDSAENGQQIMDEPMGEEEINPQTEE
VSIKEIAITHHVKEGHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVL
KKATLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLS
KEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKES
IDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKET
MTMILKAKLGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNK
LYRREIHPPFKPATGRPEDTFYFDPEFTAKTPKDSPGIPPSANAHQLFRGFSFVAITS
DDESQAMQTVGVHSIVQQLHRNSIQFTDGYEVKEDIGVGSYSVCKRCIHKATNMEFAV
KIIDKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQ
KFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAK
QLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDD
TPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQRLTAALVLRHPWIVHW
DQLPQYQLNRQDAPHLVKGAMAATYSALNRNQSPVLEPVGRSTLAQRRGIKKITSTAL
"
BASE COUNT 704 a 417 c 510 g 629 t
ORIGIN
1 atgccgctgg cgcagctggc ggacccgtgg cagaagatgg ctgtggagag cccgtccgac
61 agcgctgaga atggacagca aattatggat gaacctatgg gagaggagga gattaaccca
121 caaactgaag aagtcagtat caaagaaatt gcaatcacac atcatgtaaa ggaaggacat
181 gaaaaggcag atccttccca gtttgaactt ttaaaagtat tagggcaggg atcatttgga
241 aaggttttct tagttaaaaa aatctcaggc tctgatgcta ggcagcttta tgccatgaag
301 gtattgaaga aggccacact gaaagttcga gaccgagttc ggacaaaaat ggaacgtgat
361 atcttggtag aggttaatca tccttttatt gtcaagttgc attatgcttt tcaaactgaa
421 gggaagttgt atcttatttt ggattttctc aggggaggag atttgtttac acgcttatcc
481 aaagaggtga tgttcacaga agaagatgtc aaattctact tggctgaact tgcacttgct
541 ttagaccatc tacatagcct gggaataatt tatagagact taaaaccaga aaatatactt
601 cttgatgaag aaggtcacat caagttaaca gatttcggcc taagtaaaga gtctattgac
661 catgaaaaga aggcatattc tttttgtgga actgtggagt atatggctcc agaagtagtt
721 aatcgtcgag gtcatactca gagtgctgac tggtggtctt ttggtgtgtt aatgtttgaa
781 atgcttactg gtacactccc tttccaagga aaagatcgaa aagaaacaat gactatgatt
841 cttaaagcca aacttggaat gccacagttt ttgagtcctg aagcgcagag tcttttacga
901 atgcttttca agcgaaatcc tgcaaacaga ttaggtgcag gaccagatgg agttgaagaa
961 attaaaagac attcattttt ctcaacgata gactggaata aactgtatag aagagaaatt
1021 catccgccat ttaaacctgc aacgggcagg cctgaagata cattctattt tgatcctgag
1081 tttactgcaa aaactcccaa agattcacct ggcattccac ctagtgctaa tgcacatcag
1141 ctttttcggg ggtttagttt tgttgctatt acctcagatg atgaaagcca agctatgcag
1201 acagttggtg tacattcaat tgttcagcag ttacacagga acagtattca gtttactgat
1261 ggatatgaag taaaagaaga tattggagtt ggctcctact ctgtttgcaa gagatgtata
1321 cataaagcta caaacatgga gtttgcagtg aagattattg ataaaagcaa gagagaccca
1381 acagaagaaa ttgaaattct tcttcgttat ggacagcatc caaacattat cactctaaag
1441 gatgtatatg atgatggaaa gtatgtgtat gtagtaacag aacttatgaa aggaggtgaa
1501 ttgctggata aaattcttag acaaaaattt ttctctgaac gagaggccag tgctgtcctg
1561 ttcactataa ctaaaaccgt tgaatatctt cacgcacaag gggtggttca tcgagacttg
1621 aaacctagca acattcttta tgtggatgaa tctggtaatc cggaatctat tcgaatttgt
1681 gattttggct ttgcaaaaca gctgagagcg gaaaatggtc ttctcatgac tccttgttac
1741 actgcaaatt ttgttgcacc agaggtttta aaaagacaag gctatgatgc tgcttgtgat
1801 atatggagtc ttggtgtcct actctataca atgcttaccg gttacactcc atttgcaaat
1861 ggtcctgatg atacaccaga ggaaatattg gcacgaatag gtagcggaaa attctcactc
1921 agtggtggtt actggaattc tgtttcagac acagcaaagg acctggtgtc aaagatgctt
1981 catgtagacc ctcatcagag actgactgct gctcttgtgc tcagacatcc ttggatcgtc
2041 cactgggacc aactgccaca ataccaacta aacagacagg atgcaccaca tctagtaaag
2101 ggtgccatgg cagctacata ttctgctttg aaccgtaatc agtcaccagt tttggaacca
2161 gtaggccgct ctactcttgc tcagcggaga ggtattaaaa aaatcacctc aacagccctg
2221 tgaagtgacc tcagtgagat atttggatcc atggtgtaaa
//