LOCUS HSU07681 2628 bp mRNA linear HUM 26-JAN-1996
DEFINITION Human NAD(H)-specific isocitrate dehydrogenase alpha subunit
precursor mRNA, complete cds.
ACCESSION U07681
VERSION U07681.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2628)
AUTHORS Kim,Y.O., Oh,I.U., Park,H.S., Jeng,J., Song,B.J. and Huh,T.L.
TITLE Characterization of a cDNA clone for human NAD(+)-specific
isocitrate dehydrogenase alpha-subunit and structural comparison
with its isoenzymes from different species
JOURNAL Biochem. J. 308 (Pt 1), 63-68 (1995)
PUBMED 7755589
REFERENCE 2 (bases 1 to 2628)
AUTHORS Huh,T.
TITLE Direct Submission
JOURNAL Submitted (12-MAR-1994) Tae-Lin Huh, Kyungpook National University,
College of Natural Sciences, Genetic Engineering, 1370
Sankyuk-Dong, Pook-Ku, TaeGu 702-701, Korea
FEATURES Location/Qualifiers
source 1..2628
/db_xref="H-InvDB:HIT000217793"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="hidha"
/sex="male"
/tissue_type="heart"
/clone_lib="lambda gt 11"
/dev_stage="adult"
CDS 6..1106
/codon_start=1
/product="NAD(H)-specific isocitrate dehydrogenase alpha
subunit precursor"
/protein_id="AAA85639.1"
/translation="MAGPAWISKVSRLLGAFHNPKQVTRGFTGGVQTVTLIPGDGIGP
EISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTP
IAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVI
VDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREV
AESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSG
NIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFAT
IKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD"
sig_peptide 6..86
/note="mitochondrial leader sequence"
mat_peptide 87..1103
/product="unnamed"
BASE COUNT 745 a 533 c 570 g 780 t
ORIGIN
1 aagcgatggc tgggcccgcg tggatctcca aggtctctcg gctgctgggg gcattccaca
61 acccaaaaca ggtgaccaga ggttttactg gtggtgttca gacagtaact ttaattccag
121 gagatggtat tggcccagaa atttcagctg cagttatgaa gatttttgat gctgccaaag
181 cacctattca gtgggaggag cggaacgtca ctgccattca aggacctgga ggaaagtgga
241 tgatcccttc agaggctaaa gagtccatgg ataagaacaa gatgggcttg aaaggccctt
301 tgaagacccc aatagcagcc ggtcacccat ctatgaattt actgctgcgc aaaacatttg
361 acctttacgc gaatgtccga ccatgtgtct ctatcgaagg ctataaaacc ccttacaccg
421 atgtaaatat tgtgaccatt cgagagaaca cagaaggaga atacagtgga attgagcatg
481 tgattgttga tggagtcgtg cagagtatca agctcatcac cgagggggcg agcaagcgca
541 ttgctgagtt tgcctttgag tatgcccgga acaaccaccg gagcaacgtc acggcggtgc
601 acaaagccaa catcatgcgg atgtcagatg ggctttttct acaaaaatgc agggaagttg
661 cagaaagctg taaagatatt aaatttaatg agatgtacct tgatacagta tgtttgaata
721 tggtacaaga tccttcccaa tttgatgttc ttgttatgcc aaatttgtat ggagacatcc
781 ttagtgactt gtgtgcagga ttgatcggag gtctcggtgt gacaccaagt ggcaacattg
841 gagccaatgg ggttgcaatt tttgagtcgg ttcatgggac ggctccagac attgcaggca
901 aggacatggc gaatcccaca gccctcctgc tcagtgccgt gatgatgctg cgccacatgg
961 gactttttga ccatgctgca agaattgagg ctgcgtgttt tgctacaatt aaggacggaa
1021 agagcttgac aaaagatttg ggaggcaatg caaaatgctc agacttcaca gaggaaatct
1081 gtcgccgagt aaaagattta gattaacact tctacaactg gcatttacat cagtcactct
1141 aaatggacac cacatgaacc tctgtttaga atacctacgt atgtatgcat tggtttgctt
1201 gtttcttgac agtacatttt tagatctggc cttttcttaa caaaatctgt gcaaaagatg
1261 caggtggatg tccctaggtc tgttttcaaa gaactttttc caagtgcttg ttttatttat
1321 taagtgtcta cctggtaaat gttttttttg taaactctga gtggactgta tcatttgcta
1381 ttctaaacca ttttacactt aagttaaaat agtttctctt cagctgtaaa taacaggata
1441 cagaattaac aagagaaaat gtctaacttt ttaagaaaaa ccttattttc ttcggttttt
1501 gaaaaacata atggaaataa aacaggatat tgacataata gcacaaaatg acactcttct
1561 aaaactaaat gggcacaaga gaattttcct gggaaagttc acatcaaaaa gagtgaatgt
1621 ggtatatttc taaatgatat ggaaaataga gacagatttg tcctttacag aaattactga
1681 gtgtgaataa aaacttcaga tccaagaaat atataatgag agatataatt tttgttaata
1741 agacaaaggt aatatattgg atacaaagac acaaatgtat tgtgtgttca attattttgt
1801 tgtcttgaga tttaatattc tttccaagag cttttaatga agcagagagc tagtacttca
1861 ttttcactgg atacattttc agcatcatga gttgtcacag cctctgagcc cctgatctga
1921 agccagaagg gctgagtgta ttgtaaactt attcttgcat gttgctgtct gggaatggac
1981 cacactacag caggtagttc tgggggcgat actgccgaaa ggcccgaaca catgtatttt
2041 ggctgcaatt gaggaacttg ggatgctatt aattttgtat ttcagcaact gccccttctc
2101 ctatcccaaa gcaccaatta ctgccctctg cctcagcagt accagtataa gatgacattc
2161 caaagactgg aggcaactca gcctgagtta attcacaaaa ttatgccatg ctggggcttg
2221 agcttgagct tgggcttagg cttgggctca gcttttgacc ctcaggcatc tccttttcct
2281 tcctgtcttc ctctcccttc tcctctgctg cagcatgatt ttcttaatct tcagacactc
2341 actattttca tgaacagtta ccctctgtcc ccacaaccaa agacaactca tggcctcctt
2401 tggcccttgt gtaacattgc aaacctgtgg ctttgcaaaa tgtacccagg tcacaagggg
2461 attttttttt ttttagcaat gatatccctg tctgggtcac tttttaagct tgtaaccgcc
2521 cccccagact tataatctta aatgtatttt cctttgttta agctgctgct tcctctgttt
2581 cattggattg tgccagttat cagtggctct tgggttcaaa gtaataaa
//