LOCUS HSU07358 3365 bp mRNA linear HUM 25-MAY-1995
DEFINITION Human protein kinase (zpk) mRNA, complete cds.
ACCESSION U07358
VERSION U07358.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3365)
AUTHORS Reddy,U.R. and Pleasure,D.
TITLE Cloning of a novel putative protein kinase having a leucine zipper
domain from human brain
JOURNAL Biochem. Biophys. Res. Commun. 202 (1), 613-620 (1994)
PUBMED 8037767
REFERENCE 2 (bases 1 to 3365)
AUTHORS Reddy,U.R.
TITLE Direct Submission
JOURNAL Submitted (03-MAR-1994) Usha R. Reddy, Neurology Research,
Children's Hospital of Philadelphia, 34th Civic Centre Blvd.,
Philadelphia, PA 19104, USA
COMMENT On Oct 29, 1994 this sequence version replaced gi:507394.
FEATURES Location/Qualifiers
source 1..3365
/db_xref="H-InvDB:HIT000217659"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="NTera2/D1"
/cell_type="teratocarcinoma cells"
gene 1..3365
/gene="zpk"
5'UTR 1..98
/gene="zpk"
CDS 99..2678
/gene="zpk"
/note="putative"
/codon_start=1
/product="serine/threonine protein kinase"
/protein_id="AAA67343.1"
/translation="MACLHETRTPSPSFGGFVSTLSEASMRKLDPDTSDCTPEKDLTP
THVLQLHEQDAGGPGGAAGSPESRASRVRADEVRLQCQSGSGFLEGLFGCLRPVWTMI
GKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLGRFHGEEVAVKKVRDLKET
DIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRPVTPSLLVDWSM
GIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKELSDKSTKMSFAGTVAW
MAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSS
CPDGFKILLRQCWNSKPRNRPSFRQILLHLDIASADVLSTPQETYFKSQAEWREEVKL
HFEKIKSEGTCLHRLEEELVMRRREELRHALDIREHYERKLERANNLYMELNALMLQL
ELKERELLRREQALERRCPGLLKPHPSRGLLHGNTMEKLIKKRNVPQNLSPHSQRPDI
LKAESLLPKLDAALSGVGLPGCPKAPPSPGRSRRGKTRHRKASAKGSCGDLPGLRTAV
PPHEPGGPGSPGGLGGGPSAWEACPPALRGLHHDLLLRKMSSSSPDLLSAALGSRGRG
ATGGAGDPGSPPPARGDTPPSEGSAPGSTSPDSPGGAKGEPPPPVGPGEGVGLLGTGR
EGTSGRGGSRAGSQHLTPAALLYRAAVTRSQKRGISSEEEEGEVDSEVELTSSQRWPQ
SLNMRQSLSTFSSENPSDGEEGTASEPSPSGTPEVGSTNTDERPDERSDDMCSQGSEI
PLDPPPSEVIPGPEPSSLPIPHQELLRERGPPNSEDSDCDSTELDNSNSVDALRPPAS
LPP"
misc_feature 443..469
/gene="zpk"
/note="leucine-zipper"
3'UTR 2679..3365
/gene="zpk"
regulatory 3347..3352
/regulatory_class="polyA_signal_sequence"
/gene="zpk"
polyA_site 3365
/gene="zpk"
/note="23 A residues"
BASE COUNT 777 a 951 c 963 g 674 t
ORIGIN
1 agcatccgga gcggagctgc agcagcgccg ccttttgtgc tgcggccgcg gagcccccga
61 gggcccagtg ttcaccatca taccaggggc cagaggcgat ggcttgcctc catgagaccc
121 gaacaccctc tccttccttt gggggctttg tgtctaccct aagtgaggca tccatgcgca
181 agctggaccc agacacttct gactgcactc ccgagaagga cctgacgcct acccatgtcc
241 tgcagctaca tgagcaggat gcagggggcc cagggggagc agctgggtca cctgagagtc
301 gggcatccag agttcgagct gacgaggtgc gactgcagtg ccagagtggc agtggcttcc
361 ttgagggcct ctttggctgc ctgcgccctg tctggaccat gattggcaaa gcctactcca
421 ctgagcacaa gcagcagcag gaagaccttt gggaggtccc ctttgaggaa atcctggacc
481 tgcagtgggt gggctcaggg gcccagggtg ctgtcttcct ggggcgcttc cacggggagg
541 aggtggctgt gaagaaggtg cgagacctca aagaaaccga catcaagcac ttgcgaaagc
601 tgaagcaccc caacatcatc actttcaagg gtgtgtgcac ccaggctccc tgctactgca
661 tcctcatgga gttctgcgcc cagggccagc tgtatgaggt actgcgggct ggccgccctg
721 tcaccccctc cttactggtt gactggtcca tgggcatcgc tggtggcatg aactacctgc
781 acctgcacaa gattatccac agggatctca agtcacccaa catgctaatc acctacgacg
841 atgtggtgaa gatctcagat tttggcactt ccaaggagct gagtgacaag agcaccaaga
901 tgtcctttgc agggacagta gcctggatgg cccctgaggt gatccgcaat gaacctgtgt
961 ctgagaaggt cgacatctgg tcctttggcg tggtgctatg ggaactgctg actggtgaga
1021 tcccctacaa agacgtagat tcctcagcca ttatctgggg tgtgggaagc aacagtctcc
1081 atctgcccgt gccctccagt tgcccagatg gtttcaagat cctgcttcgc cagtgctgga
1141 atagcaaacc acgaaatcgc ccatcattcc gacagatcct gctgcatctg gacattgcct
1201 cagctgatgt actctccaca ccccaggaga cttactttaa gtcccaggca gagtggcggg
1261 aagaagtaaa actgcacttt gaaaagatta agtcagaagg gacctgtctg caccgcctag
1321 aagaggaact ggtgatgagg aggagggagg agctcagaca cgccctggac atcagggagc
1381 actatgaaag gaagctggag agagccaaca acctgtatat ggaacttaat gccctcatgt
1441 tgcagctgga actcaaggag agggagctgc tcaggcgaga gcaagcttta gagcggaggt
1501 gcccaggcct gctgaagcca cacccttccc ggggcctcct gcatggaaac acaatggaga
1561 agcttatcaa gaagaggaat gtgccacaga atctgtcacc ccatagccaa aggccagata
1621 tcctcaaggc ggagtctttg ctccctaaac tagatgcagc cctgagtggg gtggggcttc
1681 ctgggtgtcc taaggccccc ccctcaccag gacggagtcg ccgtggcaag acccgtcacc
1741 gcaaggccag cgccaagggg agctgtgggg acctgcctgg gcttcgtaca gctgtgccac
1801 cccatgaacc tggaggacca ggaagcccag ggggcctagg agggggaccc tcagcctggg
1861 aggcctgccc tcccgccctc cgtgggcttc atcatgacct cctgctccgc aaaatgtctt
1921 catcgtcccc agacctgctg tcagcagcac tagggtcccg gggccggggg gccacaggcg
1981 gagctgggga tcctggctca ccacctccgg cccggggtga caccccacca agtgagggct
2041 cagcccctgg ctccaccagc ccagattcac ctgggggagc caaaggggaa ccacctcctc
2101 cagtagggcc tggtgaaggt gtggggcttc tgggaactgg aagggaaggg acctcaggcc
2161 ggggaggaag ccgggctggg tcccagcact tgaccccagc tgcactgctg tacagggctg
2221 ccgtcacccg aagtcagaaa cgtggcatct catcggaaga ggaggaagga gaggtagaca
2281 gtgaagtaga gctgacatca agccagaggt ggcctcagag cctgaacatg cgccagtcac
2341 tatctacctt cagctcagag aatccatcag atggggagga aggcacagct agtgaacctt
2401 cccccagtgg cacacctgaa gttggcagca ccaacactga tgagcggcca gatgagcggt
2461 ctgatgacat gtgctcccag ggctcagaaa tcccactgga cccacctcct tcagaggtca
2521 tccctggccc tgaacccagc tccctgccca ttccacacca ggaacttctc agagagcggg
2581 gccctcccaa ttctgaggac tcagactgtg acagcactga attggacaac tccaacagcg
2641 ttgatgcctt gcgcccccca gcttccctcc ctccatgaaa gccactcgta ttccttgtac
2701 atagagaaat atttatatgg attatatata tatacatata tatatatata tgcgccacat
2761 aatcaacaga aagatggggc tgtcccagcc gtaagtcagg ctcgagggag actgatcccc
2821 tgaccaattc acctgataaa ctctagggac actggcagct gtggaaatga atgaggcaca
2881 gccgtagagc tgtggctaag ggcaagcccc ttcctgcccc accccattcc ttatattcag
2941 caagcaacaa ggcaatagaa aagccagggt tgtctttata ttctttatcc ccaaataata
3001 gggggtgggg ggaggggcgg tgggaggggc aggagagaaa accacttaga ctgcactttt
3061 ctgttccgtt tactctgttt acacattttg cacttgggag gagggaggct aaggctgggt
3121 cctcccctct gaggtttctc aggtggcaat gtaactcatt tttttgtccc accatttatc
3181 ttctctgccc aagccctgtc ttaaggccca gggggaggtt aggagactga tagcatgtga
3241 tggctcaggc tgaagaaccg gggttctgtt taagtccctg cttttatcct ggtgcctgat
3301 tggggtgggg actgtcctac tgtaacccct gtgaaaaacc ttgaaaaata acactccatg
3361 cagga
//