LOCUS HSU05877 1668 bp mRNA linear HUM 24-MAR-1994
DEFINITION Human clone pJS3 interferon gamma receptor accessory factor-1
(AF-1) mRNA, complete cds.
ACCESSION U05877
VERSION U05877.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1566)
AUTHORS Soh,J., Donnelly,R.J., Kotenko,S., Mariano,T.M., Cook,J.R.,
Wang,N., Emanuel,S., Schwartz,B., Miki,T. and Pestka,S.
TITLE Identification and sequence of an accessory factor required for
activation of the human interferon gamma receptor
JOURNAL Cell 76 (5), 793-802 (1994)
PUBMED 8124716
REFERENCE 2 (bases 1 to 1668)
AUTHORS Pestka,S.
TITLE Direct Submission
JOURNAL Submitted (01-FEB-1994) Sidney Pestka, UMDNJ-Robert Wood Johnson
Medical School, 675 Hoes Lane, Piscataway, NJ 08854-5635, USA
FEATURES Location/Qualifiers
source 1..1668
/db_xref="H-InvDB:HIT000217596"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="pJS3; pD9"
/cell_line="Daudi"
/cell_type="B-cell precursor"
/note="clone pJS4 (pD5) was isolated from the same cDNA
library and is identical to pJS3 at base positions
27..1629."
5'UTR 1..113
CDS 114..1127
/function="signal transduction"
/standard_name="interferon gamma receptor accessory
factor-1"
/note="second chain of the receptor"
/codon_start=1
/product="AF-1"
/protein_id="AAA16956.1"
/translation="MRPTLLWSLLLLLGVFAAAAAAPPDPLSQLPAPQHPKIRLYNAE
QVLSWEPVALSNSTRPVVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPS
AGFPMDFNVTLRLRAELGALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFS
SPFDIADTSTAFFCYYVHYWEKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLLW
NKSNIFRVGHLSNISCYETMADASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGL
IKYWFHTPPSIPLQIEEYLKDPTQPILEALDKDSSPKDDVWDSVSIISFPEKEQEDVL
QTL"
sig_peptide 114..194
mat_peptide 195..1124
/product="unnamed"
3'UTR 1128..1668
BASE COUNT 409 a 441 c 400 g 418 t
ORIGIN
1 ggccctgcgc gccctgcgct cgccatggcg gtttgggcgg cgacgtgagc ggctccgcgg
61 accccgagcg gggccccggc cgcgacctga gccgccgccg agcgcccggg gccatgcgac
121 cgacgctgct gtggtcgctg ctgctgctgc tcggagtctt cgccgccgcc gccgcggccc
181 cgccagaccc tctttcccag ctgcccgctc ctcagcaccc gaagattcgc ctgtacaacg
241 cagagcaggt cctgagttgg gagccagtgg ccctgagcaa tagcacgagg cctgttgtct
301 accaagtgca gtttaaatac accgacagta aatggttcac ggccgacatc atgtccatag
361 gggtgaattg tacacagatc acagcaacag agtgtgactt cactgccgcc agtccctcag
421 caggcttccc aatggatttc aatgtcactc tacgccttcg agctgagctg ggagcactcc
481 attctgcctg ggtgacaatg ccttggtttc aacactatcg gaatgtgact gtcgggcctc
541 cagaaaacat tgaggtgacc ccaggagaag gctccctcat catcaggttc tcctctccct
601 ttgacatcgc tgatacctcc acggcctttt tttgttatta tgtccattac tgggaaaaag
661 gaggaatcca acaggtcaaa ggccctttca gaagcaactc catttcattg gataacttaa
721 aaccctccag agtgtactgt ttacaagtcc aggcacaact gctttggaac aaaagtaaca
781 tctttagagt cgggcattta agcaacatat cttgctacga aacaatggca gatgcctcca
841 ctgagcttca gcaagtcatc ctgatctccg tgggaacatt ttcgttgctg tcggtgctgg
901 caggagcctg tttcttcctg gtcctgaaat atagaggcct gattaaatac tggtttcaca
961 ctccaccaag catcccatta cagatagaag agtatttaaa agacccaact cagcccatct
1021 tagaggcctt ggacaaggac agctcaccaa aggatgacgt ctgggactct gtgtccatta
1081 tctcgtttcc ggaaaaggag caagaagatg ttctccaaac gctttgaacc aaagcatggg
1141 cctagcccac tggctccctg gaagagatca agccatcgga gctgctagag ttctgtctgg
1201 actttccaga gaccagtatt cccttttgct gcctctaaaa ggcctgtccc tgcagacatg
1261 agagacagca ggtctcatgg gggtgacaag cttttttttt ttttcttaaa gaattttcaa
1321 aatcaaattc cagaatgatt ttacggagat atcccaggaa aattaaggct tctcttaaac
1381 actaaaaagg catgtaattg cttgttagca aaatggatat gacacatctc tgatactttt
1441 ttcattattg gttgggctga gcagtcagaa gacctggtcg tcgtcttgac tttggcaaat
1501 gagccggagc cccttgggca ggtcacacaa cctgtcccag cgagggacac tgagtggccc
1561 ttcatgtaca tccatggtgt gctggcttaa aatgtaatta atcttgtaaa tatactccta
1621 gtaatttaag attttgtttt taaactggaa ataaaagatt gtatagtg
//