LOCUS HSU05875 2214 bp mRNA linear HUM 24-MAR-1994
DEFINITION Human clone pSK1 interferon gamma receptor accessory factor-1
(AF-1) mRNA, complete cds.
ACCESSION U05875
VERSION U05875.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2214)
AUTHORS Soh,J., Donnelly,R.J., Kotenko,S., Mariano,T.M., Cook,J.R.,
Wang,N., Emanuel,S., Schwartz,B., Miki,T. and Pestka,S.
TITLE Identification and sequence of an accessory factor required for
activation of the human interferon gamma receptor
JOURNAL Cell 76 (5), 793-802 (1994)
PUBMED 8124716
REFERENCE 2 (bases 1 to 2214)
AUTHORS Pestka,S.
TITLE Direct Submission
JOURNAL Submitted (01-FEB-1994) Sidney Pestka, UMDNJ-Robert Wood Johnson
Medical School, 675 Hoes Lane, Piscataway, NJ 08854-5635, USA
FEATURES Location/Qualifiers
source 1..2214
/db_xref="H-InvDB:HIT000217595"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="pSK1"
/cell_line="M426 cells"
/cell_type="lung cells"
/tissue_type="lung fibroblasts"
/dev_stage="embryo"
5'UTR 1..648
CDS 649..1662
/function="signal transduction"
/standard_name="interferon gamma receptor accessory
factor-1"
/note="second chain of the receptor"
/codon_start=1
/product="AF-1"
/protein_id="AAA16955.1"
/translation="MRPTLLWSLLLLLGVFAAAAAAPPDPLSQLPAPQHPKIRLYNAE
QVLSWEPVALSNSTRPVVYRVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPS
AGFPMDFNVTLRLRAELGALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFS
SPFDIADTSTAFFCYYVHYWEKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLLW
NKSNIFRVGHLSNISCYETMADASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGL
IKYWFHTPPSIPLQIEEYLKDPTQPILEALDKDSSPKDDVWDSVSIISFPEKEQEDVL
QTL"
sig_peptide 649..729
mat_peptide 730..1659
/product="unnamed"
3'UTR 1663..2214
polyA_site 2214
/note="39 A residues"
BASE COUNT 494 a 595 c 628 g 497 t
ORIGIN
1 gttgactgga ggcggaggtt gcagtgagcc gagatcgccc cactgcactc cagcctggtg
61 actccgtctc aaaaaaaagg ggaggggggc gggggagagt tgaaagctta atatgtactt
121 tgggggctat taaagcaaac atttcgacta aaggggcgaa tcctcgaatt gtgcgatcaa
181 gcacccgaga ggagagttgg ggggggtcag gaggggtggg ggctccaggg aacgcccggg
241 ggcctgggcc ggggtctcgc ggggcccttc cggaaggatc gcggcccccg aaggtgggcg
301 tcccgcgggg ctccagtctc caggacgttc cgggaggctc cgcgctctgg gaggccggct
361 gcgtggggtc cccgcgctgc agccgcagag gccccccagg gccgcggttc ccggagcggg
421 aaagtcccgc gcgggggcgg tggcctcggg ggcgggacgg ggcgggggcg ggggcgcggg
481 cggccgagcc gaatcccctc caccgggacg ccccgctgcc gctcgggaag aggcgggccc
541 tgcgcgccct gcgctcgcca tggcggtttg ggcggcgacg tgagcggctc cgcggacccc
601 gagcggggcc ccggccgcga cctgagccgc cgccgagcgc ccggggccat gcgaccgacg
661 ctgctgtggt cgctgctgct gctgctcgga gtcttcgccg ccgccgccgc ggccccgcca
721 gaccctcttt cccagctgcc cgctcctcag cacccgaaga ttcgcctgta caacgcagag
781 caggtcctga gttgggagcc agtggccctg agcaatagca cgaggcctgt tgtctaccga
841 gtgcagttta aatacaccga cagtaaatgg ttcacggccg acatcatgtc cataggggtg
901 aattgtacac agatcacagc aacagagtgt gacttcactg ccgccagtcc ctcagcaggc
961 ttcccaatgg atttcaatgt cactctacgc cttcgagctg agctgggagc actccattct
1021 gcctgggtga caatgccttg gtttcaacac tatcggaatg tgactgtcgg gcctccagaa
1081 aacattgagg tgaccccagg agaaggctcc ctcatcatca ggttctcctc tccctttgac
1141 atcgctgata cctccacggc ctttttttgt tattatgtcc attactggga aaaaggagga
1201 atccaacagg tcaaaggccc tttcagaagc aactccattt cattggataa cttaaaaccc
1261 tccagagtgt actgtttaca agtccaggca caactgcttt ggaacaaaag taacatcttt
1321 agagtcgggc atttaagcaa catatcttgc tacgaaacaa tggcagatgc ctccactgag
1381 cttcagcaag tcatcctgat ctccgtggga acattttcgt tgctgtcggt gctggcagga
1441 gcctgtttct tcctggtcct gaaatataga ggcctgatta aatactggtt tcacactcca
1501 ccaagcatcc cattacagat agaagagtat ttaaaagacc caactcagcc catcttagag
1561 gccttggaca aggacagctc accaaaggat gacgtctggg actctgtgtc cattatctcg
1621 tttccggaaa aggagcaaga agatgttctc caaacgcttt gaaccaaagc atgggcctag
1681 cccactggct ccctggaaga gatcaagcca tcggagctgc tagagttctg tctggacttt
1741 ccagagacca gtattccctt ttgctgcctc taaaaggcct gtccctgcag acatgagaga
1801 cagcaggtct catgggggtg acaagctttt tttttttttt cttaaagaat tttcaaaatc
1861 aaattccaga atgattttac ggagatatcc caggaaaatt aaggcttctc ttaaacacta
1921 aaaaggcatg taattgcttg ttagcaaaat ggatatgaca catctctgat acttttttca
1981 ttattggttg ggctgagcag tcagaagacc tggtcgtcgt cttgactttg gcaaatgagc
2041 cggagcccct tgggcaggtc acacaacctg tcccagcgag ggacactgag tggcccttca
2101 tgtacatcca tggtgtgctg gcttaaaatg taattaatct tgtaaatata ctcctagtaa
2161 tttaagattt tgtttttaaa ctggaaataa aagattgtat agtgcatgtt tttt
//