LOCUS HSU04899 1915 bp mRNA linear HUM 07-MAR-1995
DEFINITION Human orphan hormone nuclear receptor RORalpha3 mRNA, complete cds.
ACCESSION U04899
VERSION U04899.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 9 to 1915)
AUTHORS Giguere,V., Tini,M., Flock,G., Ong,E., Evans,R.M. and
Otulakowski,G.
TITLE Isoform-specific amino-terminal domains dictate DNA-binding
properties of ROR alpha, a novel family of orphan hormone nuclear
receptors
JOURNAL Genes Dev. 8 (5), 538-553 (1994)
PUBMED 7926749
REFERENCE 2 (bases 1 to 1915)
AUTHORS Giguere,V.
TITLE Direct Submission
JOURNAL Submitted (06-JAN-1994) Vincent Giguere, Endocrine Research,
Research Institute, Hospital for Sick Children, 555 University
Avenue, Toronto, Ontario M5G 1X8, Canada
FEATURES Location/Qualifiers
source 1..1915
/db_xref="H-InvDB:HIT000217574"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="lambdahT19"
/sex="male"
/tissue_type="testis"
/clone_lib="lambda gt11 from CloneTech"
/dev_stage="adult"
5'UTR 1..78
CDS 79..1725
/codon_start=1
/product="RORalpha3"
/protein_id="AAA62660.1"
/translation="MNEGAPGDSDLETEARVPWSIMGHCLRTGQARMSATPTPAGEGA
RSSSTCSSLSRLFWSQLEHINWDGATAKNFINLREFFSFLLPALRKAQIEIIPCKICG
DKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLA
VGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGL
TELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPAS
GFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIE
NYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIR
MCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSA
FVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGR
HTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG"
3'UTR 1726..1915
regulatory 1891..1895
/regulatory_class="polyA_signal_sequence"
BASE COUNT 592 a 428 c 442 g 453 t
ORIGIN
1 gaattcgggg actccatagt acactggggc aaagcacagc cccagtttct ggaggcagat
61 gggtaaccag gaaaaggcat gaatgagggg gccccaggag acagtgactt agagactgag
121 gcaagagtgc cgtggtcaat catgggtcat tgtcttcgaa ctggacaggc cagaatgtct
181 gccacaccca cacctgcagg tgaaggagcc agaagctctt caacctgtag ctccctgagc
241 aggctgttct ggtctcaact tgagcacata aactgggatg gagccacagc caagaacttt
301 attaatttaa gggagttctt ctcttttctg ctccctgcat tgagaaaagc tcaaattgaa
361 attattccat gcaagatctg tggagacaaa tcatcaggaa tccattatgg tgtcattaca
421 tgtgaaggct gcaagggctt tttcaggaga agtcagcaaa gcaatgccac ctactcctgt
481 cctcgtcaga agaactgttt gattgatcga accagtagaa accgctgcca acactgtcga
541 ttacagaaat gccttgccgt agggatgtct cgagatgctg taaaatttgg ccgaatgtca
601 aaaaagcaga gagacagctt gtatgcagaa gtacagaaac accggatgca gcagcagcag
661 cgcgaccacc agcagcagcc tggagaggct gagccgctga cgcccaccta caacatctcg
721 gccaacgggc tgacggaact tcacgacgac ctcagtaact acattgacgg gcacacccct
781 gaggggagta aggcagactc cgccgtcagc agcttctacc tggacataca gccttcccca
841 gaccagtcag gtcttgatat caatggaatc aaaccagaac caatatgtga ctacacacca
901 gcatcaggct tctttcccta ctgttcgttc accaacggcg agacttcccc aactgtgtcc
961 atggcagaat tagaacacct tgcacagaat atatctaaat cgcatctgga aacctgccaa
1021 tacttgagag aagagctcca gcagataacg tggcagacct ttttacagga agaaattgag
1081 aactatcaaa acaagcagcg ggaggtgatg tggcaattgt gtgccatcaa aattacagaa
1141 gctatacagt atgtggtgga gtttgccaaa cgcattgatg gatttatgga actgtgtcaa
1201 aatgatcaaa ttgtgcttct aaaagcaggt tctctagagg tggtgtttat cagaatgtgc
1261 cgtgcctttg actctcagaa caacaccgtg tactttgatg ggaagtatgc cagccccgac
1321 gtcttcaaat ccttaggttg tgaagacttt attagctttg tgtttgaatt tggaaagagt
1381 ttatgttcta tgcacctgac tgaagatgaa attgcattat tttctgcatt tgtactgatg
1441 tcagcagatc gctcatggct gcaagaaaag gtaaaaattg aaaaactgca acagaaaatt
1501 cagctagctc ttcaacacgt cctacagaag aatcaccgag aagatggaat actaacaaag
1561 ttaatatgca aggtgtctac attaagagcc ttatgtggac gacatacaga aaagctaatg
1621 gcatttaaag caatataccc agacattgtg cgacttcatt ttcctccatt atacaaggag
1681 ttgttcactt cagaatttga gccagcaatg caaattgatg ggtaaatgtt atcacctaag
1741 cacttctaga atgtctgaag tacaaacatg aaaaacaaac aaaaaaatta accgagacac
1801 tttatatggc cctgcacaga cctggagcgc cacacactgc acatcttttg gtgatcgggg
1861 tcaggcaaag gaggggaaac aatgaaaaca aataaagttg aacttgtttt tctca
//