LOCUS HSU04898 1950 bp mRNA linear HUM 07-MAR-1995
DEFINITION Human orphan hormone nuclear receptor RORalpha2 mRNA, complete cds.
ACCESSION U04898
VERSION U04898.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1950)
AUTHORS Giguere,V., Tini,M., Flock,G., Ong,E., Evans,R.M. and
Otulakowski,G.
TITLE Isoform-specific amino-terminal domains dictate DNA-binding
properties of ROR alpha, a novel family of orphan hormone nuclear
receptors
JOURNAL Genes Dev. 8 (5), 538-553 (1994)
PUBMED 7926749
REFERENCE 2 (bases 1 to 1950)
AUTHORS Giguere,V.
TITLE Direct Submission
JOURNAL Submitted (06-JAN-1994) Vincent Giguere, Endocrine Research,
Research Institute, Hospital for Sick Children, 555 University
Avenue, Toronto, Ontario M5G 1X8, Canada
FEATURES Location/Qualifiers
source 1..1950
/db_xref="H-InvDB:HIT000217573"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="lambdahT3"
/sex="male"
/tissue_type="testis"
/clone_lib="lambda gt11 human testis from CloneTech"
/dev_stage="adult"
5'UTR 1..89
CDS 90..1760
/codon_start=1
/product="RORalpha2"
/protein_id="AAA62659.1"
/translation="MNEGAPGDSDLETEARVPWSIMGHCLRTGQARMSATPTPAGEGA
RRDELFGILQILHQCILSSGDAFVLTGVCCSWRQNGKPPYSQKEDKEVQTGYMNAQIE
IIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQH
CRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPT
YNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEP
ICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQ
TFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAG
SLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTE
DEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVS
TLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG"
3'UTR 1761..1950
regulatory 1929..1934
/regulatory_class="polyA_signal_sequence"
BASE COUNT 604 a 431 c 450 g 465 t
ORIGIN
1 ccatctgtct gatcaccttg gactccatag tacactgggg caaagcacag ccccagtttc
61 tggaggcaga tgggtaacca ggaaaaggca tgaatgaggg ggccccagga gacagtgact
121 tagagactga ggcaagagtg ccgtggtcaa tcatgggtca ttgtcttcga actggacagg
181 ccagaatgtc tgccacaccc acacctgcag gtgaaggagc cagaagggat gaactttttg
241 ggattctcca aatactccat cagtgtatcc tgtcttcagg tgatgctttt gttcttactg
301 gcgtctgttg ttcctggagg cagaatggca agccaccata ttcacaaaag gaagataagg
361 aagtacaaac tggatacatg aatgctcaaa ttgaaattat tccatgcaag atctgtggag
421 acaaatcatc aggaatccat tatggtgtca ttacatgtga aggctgcaag ggctttttca
481 ggagaagtca gcaaagcaat gccacctact cctgtcctcg tcagaagaac tgtttgattg
541 atcgaaccag tagaaaccgc tgccaacact gtcgattaca gaaatgcctt gccgtaggga
601 tgtctcgaga tgctgtaaaa tttggccgaa tgtcaaaaaa gcagagagac agcttgtatg
661 cagaagtaca gaaacaccgg atgcagcagc agcagcgcga ccaccagcag cagcctggag
721 aggctgagcc gctgacgccc acctacaaca tctcggccaa cgggctgacg gaacttcacg
781 acgacctcag taactacatt gacgggcaca cccctgaggg gagtaaggca gactccgccg
841 tcagcagctt ctacctggac atacagcctt ccccagacca gtcaggtctt gatatcaatg
901 gaatcaaacc agaaccaata tgtgactaca caccagcatc aggcttcttt ccctactgtt
961 cgttcaccaa cggcgagact tccccaactg tgtccatggc agaattagaa caccttgcac
1021 agaatatatc taaatcgcat ctggaaacct gccaatactt gagagaagag ctccagcaga
1081 taacgtggca gaccttttta caggaagaaa ttgagaacta tcaaaacaag cagcgggagg
1141 tgatgtggca attgtgtgcc atcaaaatta cagaagctat acagtatgtg gtggagtttg
1201 ccaaacgcat tgatggattt atggaactgt gtcaaaatga tcaaattgtg cttctaaaag
1261 caggttctct agaggtggtg tttatcagaa tgtgccgtgc ctttgactct cagaacaaca
1321 ccgtgtactt tgatgggaag tatgccagcc ccgacgtctt caaatcctta ggttgtgaag
1381 actttattag ctttgtgttt gaatttggaa agagtttatg ttctatgcac ctgactgaag
1441 atgaaattgc attattttct gcatttgtac tgatgtcagc agatcgctca tggctgcaag
1501 aaaaggtaaa aattgaaaaa ctgcaacaga aaattcagct agctcttcaa cacgtcctac
1561 agaagaatca ccgagaagat ggaatactaa caaagttaat atgcaaggtg tctacattaa
1621 gagccttatg tggacgacat acagaaaagc taatggcatt taaagcaata tacccagaca
1681 ttgtgcgact tcattttcct ccattataca aggagttgtt cacttcagaa tttgagccag
1741 caatgcaaat tgatgggtaa atgttatcac ctaagcactt ctagaatgtc tgaagtacaa
1801 acatgaaaaa caaacaaaaa aattaaccga gacactttat atggccctgc acagacctgg
1861 agcgccacac actgcacatc ttttggtgat cggggtcagg caaaggaggg gaaacaatga
1921 aaacaaataa agttgaactt gtttttctca
//