LOCUS HSU03877 2512 bp mRNA linear HUM 30-APR-1995
DEFINITION Human extracellular protein (S1-5) mRNA, complete cds.
ACCESSION U03877
VERSION U03877.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2512)
AUTHORS Lecka-Czernik,B., Lumpkin,C.K. Jr. and Goldstein,S.
TITLE An overexpressed gene transcript in senescent and quiescent human
fibroblasts encoding a novel protein in the epidermal growth
factor-like repeat family stimulates DNA synthesis
JOURNAL Mol. Cell. Biol. 15 (1), 120-128 (1995)
PUBMED 7799918
REFERENCE 2 (bases 1 to 2512)
AUTHORS Lecka-Czernik,B.
TITLE Direct Submission
JOURNAL Submitted (01-DEC-1993) Beata Lecka-Czernik, Medicine, University
of Arkansas for Medical Sciences, 4301 W. Markham, Little Rock, AR
72205-7199, USA
FEATURES Location/Qualifiers
source 1..2512
/db_xref="H-InvDB:HIT000217527"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="S1-5"
/sex="male"
/cell_line="WS8"
/cell_type="fibroblast"
/tissue_type="skin"
/clone_lib="sW8"
/dev_stage="adult"
gene 1..2512
/gene="S1-5"
mRNA 1..2512
/gene="S1-5"
5'UTR 1..237
/gene="S1-5"
CDS 238..1401
/gene="S1-5"
/function="stimulation of DNA synthesis in vitro"
/note="contains 5 EGF-like domains"
/codon_start=1
/product="extracellular protein"
/protein_id="AAA65590.1"
/translation="MATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIP
SNPSHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKR
GEQCVDIDECTIPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQ
QCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGY
QVVRSRTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVS
NAMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLR
QTSPVSAMLVLVKSLSGPREHIVDLEMLTVSSIGTFRTSSVLRLTIIVGPFSF"
sig_peptide 238..291
/gene="S1-5"
3'UTR 1399..2512
/gene="S1-5"
regulatory 1840..1845
/regulatory_class="polyA_signal_sequence"
/gene="S1-5"
polyA_site 1860..1876
/gene="S1-5"
regulatory 1936..1941
/regulatory_class="polyA_signal_sequence"
/gene="S1-5"
polyA_site 1955..1956
/gene="S1-5"
regulatory 2115..2120
/regulatory_class="polyA_signal_sequence"
/gene="S1-5"
regulatory 2475..2486
/regulatory_class="polyA_signal_sequence"
/gene="S1-5"
polyA_site 2496..2512
/gene="S1-5"
BASE COUNT 803 a 507 c 512 g 690 t
ORIGIN
1 caatgcactg acggatatga gtgggatcct gtgagacagc aatgcaaaga tattgatgaa
61 tgtgacattg tcccagacgc ttgtaaaggt ggaatgaagt gtgtcaacca ctatggagga
121 tacctctgcc ttccgaaaac agcccagatt attgtcaata atgaacagcc tcagcaggaa
181 acacaaccag cagaaggaac ctcaggggca accaccgggg ttgtagctgc cagcagcatg
241 gcaaccagtg gagtgttgcc cgggggtggt tttgtggcca gtgctgctgc agtcgcaggc
301 cctgaaatgc agactggccg aaataacttt gtcatccggc ggaacccagc tgaccctcag
361 cgcattccct ccaacccttc ccaccgtatc cagtgtgcag caggctacga gcaaagtgaa
421 cacaacgtgt gccaagacat agacgagtgc actgcaggga cgcacaactg tagagcagac
481 caagtgtgca tcaatttacg gggatccttt gcatgtcagt gccctcctgg atatcagaag
541 cgaggggagc agtgcgtaga catagatgaa tgtaccatcc ctccatattg ccaccaaaga
601 tgcgtgaata caccaggctc attttattgc cagtgcagtc ctgggtttca attggcagca
661 aacaactata cctgcgtaga tataaatgaa tgtgatgcca gcaatcaatg tgctcagcag
721 tgctacaaca ttcttggttc attcatctgt cagtgcaatc aaggatatga gctaagcagt
781 gacaggctca actgtgaaga cattgatgaa tgcagaacct caagctacct gtgtcaatat
841 caatgtgtca atgaacctgg gaaattctca tgtatgtgcc cccagggata ccaagtggtg
901 agaagtagaa catgtcaaga tataaatgag tgtgagacca caaatgaatg ccgggaggat
961 gaaatgtgtt ggaattatca tggcggcttc cgttgttatc cacgaaatcc ttgtcaagat
1021 ccctacattc taacaccaga gaaccgatgt gtttgcccag tctcaaatgc catgtgccga
1081 gaactgcccc agtcaatagt ctacaaatac atgagcatcc gatctgatag gtctgtgcca
1141 tcagacatct tccagataca ggccacaact atttatgcca acaccatcaa tacttttcgg
1201 attaaatctg gaaatgaaaa tggagagttc tacctacgac aaacaagtcc tgtaagtgca
1261 atgcttgtgc tcgtgaagtc attatcagga ccaagagaac atatcgtgga cctggagatg
1321 ctgacagtca gcagtatagg gaccttccgc acaagctctg tgttaagatt gacaataata
1381 gtggggccat tttcatttta gtcttttcta agagtcaacc acaggcattt aagtcagcca
1441 aagaatattg ttaccttaaa gcactatttt atttatagat atatctagtg catctacatc
1501 tctatactgt acactcaccc ataacaaaca attacaccat ggtataaagt gggcatttaa
1561 tatgtaaaga ttcaaagttt gtctttatta ctatatgtaa attagacatt aatccactaa
1621 actggtcttc ttcaagagag ctaagtatac actatctggt gaaacttgga ttctttccta
1681 taaaagtggg accaagcaat gatgatcttc tgtggtgctt aaggaaactt actagagctc
1741 cactaacagt ctcataagga ggcagccatc ataaccattg aatagcatgc aagggtaaga
1801 atgagttttt aactgctttg taagaaaatg gaaaaggtca ataaagatat atttctttag
1861 aaaatgggga tctgccatat ttgtgttggt ttttattttc atatccagcc taaaggtggt
1921 tgtttattat atagtaataa atcattgctg tacaacatgc tggtttctgt agggtatttt
1981 taattttgtc agaaatttta gattgtgaat attttgtaaa aaacagtaag caaaattttc
2041 cagaattccc aaaatgaacc agataccccc tagaaaatta tactattgag aaatctatgg
2101 ggaggatatg agaaaataaa ttccttctaa accacattgg aactgacctg aagaagcaaa
2161 ctcggaaaat ataataacat ccctgaattc aggcattcac aagatgcaga acaaaatgga
2221 taaaaggtat ttcactggag aagttttaat ttctaagtaa aatttaaatc ctaacacttc
2281 actaatttat aactaaaatt tctcatcttc gtacttgatg ctcacagagg aagaaaatga
2341 tgatggtttt tattcctggc atccagagtg acagtgaact taagcaaatt accctcctac
2401 ccaattctat ggaatatttt atacgtctcc ttgtttaaaa tctgactgct ttactttgat
2461 gtatcatatt tttaaataaa aataaatatt cctttagaag atcactctaa aa
//