LOCUS HSU03464 4449 bp mRNA linear HUM 23-APR-1997
DEFINITION Human P-type ATPase ATP7B mRNA, complete cds.
ACCESSION U03464
VERSION U03464.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4449)
AUTHORS Bull,P.C., Thomas,G.R., Rommens,J.M., Forbes,J.R. and Cox,D.W.
TITLE The Wilson disease gene is a putative copper transporting P-type
ATPase similar to the Menkes gene
JOURNAL Nat. Genet. 5 (4), 327-337 (1993)
PUBMED 8298639
REFERENCE 2 (bases 1 to 4449)
AUTHORS Cox,D.W.
TITLE Direct Submission
JOURNAL Submitted (12-NOV-1993) Diane W. Cox, Genetics, Research Institute,
The Hospital for Sick Children, 555, University Avenue, Toronto,
Ontario M5G 1X8, Canada
COMMENT On Apr 23, 1997 this sequence version replaced gi:434682.
FEATURES Location/Qualifiers
source 1..4449
/db_xref="H-InvDB:HIT000217501"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="13"
/map="q14.3"
CDS 1..4398
/function="P-type ATPase"
/codon_start=1
/product="ATP7B"
/protein_id="AAB52902.1"
/translation="MPEQERQITAREGASRKILSKLSLPTRAWEPAMKKSFAFDNVGY
EGGLDGLGPSSQVATSTVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKY
VPSVVCLQQVCHQIGDMGFEASIAEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSS
IEGKVRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAPLS
LGPIDIERLQSTNPKRPLSSANQNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIE
ENIGQLLGVQSIQVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGS
GTDHRSSSSHSPGSPPRNQVQGTCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISV
SLAEGTATVLYNPAVISPEELRAAIEDMGFEASVVSESCSTNPLGNHSAGNSMVQTTD
GTPTSLQEVAPHTGRLPANHAPDILAKSPQSTRAVAPQKCFLQIKGMTCASCVSNIER
NLQKEAGVLSVLVALMAGKAEIKYDPEVIQPLEIAQFIQDLGFEAAVMEDYAGSDGNI
ELTITGMTCASCVHNIESKLTRTNGITYASVALATSKALVKFDPEIIGPRDIIKIIEE
IGFHASLAQRNPNAHHLDHKMEIKQWKKSFLCSLVFGIPVMALMIYMLIPSNEPHQSM
VLDHNIIPGLSILNLIFFILCTFVQLLGGWYFYVQAYKSLRHRSANMDVLIVLATSIA
YVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIALGRWLEHLAKSKTSEALAKLMSL
QATEATVVTLGEDNLIIREEQVPMELVQRGDIVRVVPGGKFPVDGKVLEGNTMADESL
ITGEAMPVTKKPGSTVIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKAPIQ
QLADRFSGYFVPFIIIMSTLTLVVWIVIGFIDFGVVQKYFPNPNKHISQTEVIIRFAF
QTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTG
TITHGVPRVMRVLLLGDVATLPLRKVLAVVGTAEASSEHPLGVAVTKYCKEELGTETL
GYCTDFQAVPGCGIGCKVSNVEGILAHSERPLSAPASHLNEAGSLPAEKDAAPQTFSV
LIGNREWLRRNGLTISSDVSDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKQEAAL
AVHTLQSMGVDVVLITGDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQNKGKKV
AMVGDGVNDSPALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRR
IRINLVLALIYNLVGIPIAAGVFMPIGIVLQPWMGSAAMAASSVSVVLSSLQLKCYKK
PDLERYEAQAHGHMKPLTASQVSVHIGMDDRWRDSPRATPWDQVSYVSQVSLSSLTSD
KPSRHSAAADDDGDKWSLLLNGRDEEQYI"
BASE COUNT 1069 a 1157 c 1220 g 1003 t
ORIGIN
1 atgcctgaac aggagagaca gatcacagcc agagaagggg ccagtcggaa aatcttatct
61 aagctttctt tgcctacccg tgcctgggaa ccagcaatga agaagagttt tgcttttgac
121 aatgttggct atgaaggtgg tctggatggc ctgggccctt cttctcaggt ggccaccagc
181 acagtcagga tcttgggcat gacttgccag tcatgtgtga agtccattga ggacaggatt
241 tccaatttga aaggcatcat cagcatgaag gtttccctgg aacaaggcag tgccactgtg
301 aaatatgtgc catcggttgt gtgcctgcaa caggtttgcc atcaaattgg ggacatgggc
361 ttcgaggcca gcattgcaga aggaaaggca gcctcctggc cctcaaggtc cttgcctgcc
421 caggaggctg tggtcaagct ccgggtggag ggcatgacct gccagtcctg tgtcagctcc
481 attgaaggca aggtccggaa actgcaagga gtagtgagag tcaaagtctc actcagcaac
541 caagaggccg tcatcactta tcagccttat ctcattcagc ccgaagacct cagggaccat
601 gtaaatgaca tgggatttga agctgccatc aagagcaaag tggctccctt aagcctggga
661 ccaattgata ttgagcggtt acaaagcact aacccaaaga gacctttatc ttctgctaac
721 cagaatttta ataattctga gaccttgggg caccaaggaa gccatgtggt caccctccaa
781 ctgagaatag atggaatgca ttgtaagtct tgcgtcttga atattgaaga aaatattggc
841 cagctcctag gggttcaaag tattcaagtc tccttggaga acaaaactgc ccaagtaaag
901 tatgaccctt cttgtaccag cccagtggct ctgcagaggg ctatcgaggc acttccacct
961 gggaatttta aagtttctct tcctgatgga gccgaaggga gtgggacaga tcacaggtct
1021 tccagttctc attcccctgg ctccccaccg agaaaccagg tccagggcac atgcagtacc
1081 actctgattg ccattgccgg catgacctgt gcatcctgtg tccattccat tgaaggcatg
1141 atctcccaac tggaaggggt gcagcaaata tcggtgtctt tggccgaagg gactgcaaca
1201 gttctttata atcccgctgt aattagccca gaagaactca gagctgctat agaagacatg
1261 ggatttgagg cttcagtcgt ttctgaaagc tgttctacta accctcttgg aaaccacagt
1321 gctgggaatt ccatggtgca aactacagat ggtacaccta catctctgca ggaagtggct
1381 ccccacactg ggaggctccc tgcaaaccat gccccggaca tcttggcaaa gtccccacaa
1441 tcaaccagag cagtggcacc gcagaagtgc ttcttacaga tcaaaggcat gacctgtgca
1501 tcctgtgtgt ctaacataga aaggaatctg cagaaagaag ctggtgttct ctccgtgttg
1561 gttgccttga tggcaggaaa ggcagagatc aagtatgacc cagaggtcat ccagcccctc
1621 gagatagctc agttcatcca ggacctgggt tttgaggcag cagtcatgga ggactacgca
1681 ggctccgatg gcaacattga gctgacaatc acagggatga cctgcgcgtc ctgtgtccac
1741 aacatagagt ccaaactcac gaggacaaat ggcatcactt atgcctccgt tgcccttgcc
1801 accagcaaag cccttgttaa gtttgacccg gaaattatcg gtccacggga tattatcaaa
1861 attattgagg aaattggctt tcatgcttcc ctggcccaga gaaaccccaa cgctcatcac
1921 ttggaccaca agatggaaat aaagcagtgg aagaagtctt tcctgtgcag cctggtgttt
1981 ggcatccctg tcatggcctt aatgatctat atgctgatac ccagcaacga gccccaccag
2041 tccatggtcc tggaccacaa catcattcca ggactgtcca ttctaaatct catcttcttt
2101 atcttgtgta cctttgtcca gctcctcggt gggtggtact tctacgttca ggcctacaaa
2161 tctctgagac acaggtcagc caacatggac gtgctcatcg tcctggccac aagcattgct
2221 tatgtttatt ctctggtcat cctggtggtt gctgtggctg agaaggcgga gaggagccct
2281 gtgacattct tcgacacgcc ccccatgctc tttgtgttca ttgccctggg ccggtggctg
2341 gaacacttgg caaagagcaa aacctcagaa gccctggcta aactcatgtc tctccaagcc
2401 acagaagcca ccgttgtgac ccttggtgag gacaatttaa tcatcaggga ggagcaagtc
2461 cccatggagc tggtgcagcg gggcgatatc gtcagggtgg tccctggggg aaagtttcca
2521 gtggatggga aagtcctgga aggcaatacc atggctgatg agtccctcat cacaggagaa
2581 gccatgccag tcactaagaa acccggaagc actgtaattg cggggtctat aaatgcacat
2641 ggctctgtgc tcattaaagc tacccacgtg ggcaatgaca ccactttggc tcagattgtg
2701 aaactggtgg aagaggctca gatgtcaaag gcacccattc agcagctggc tgaccggttt
2761 agtggatatt ttgtcccatt tatcatcatc atgtcaactt tgacgttggt ggtatggatt
2821 gtaatcggtt ttatcgattt tggtgttgtt cagaaatact ttcctaaccc caacaagcac
2881 atctcccaga cagaggtgat catccggttt gctttccaga cgtccatcac ggtgctgtgc
2941 attgcctgcc cctgctccct ggggctggcc acgcccacgg ctgtcatggt gggcaccggg
3001 gtggccgcgc agaacggcat cctcatcaag ggaggcaagc ccctggagat ggcgcacaag
3061 ataaagactg tgatgtttga caagactggc accattaccc atggcgtccc cagggtcatg
3121 cgggtgctcc tgctggggga tgtggccaca ctgcccctca ggaaggttct ggctgtggtg
3181 gggactgcgg aggccagcag tgaacacccc ttgggcgtgg cagtcaccaa atactgtaaa
3241 gaggaacttg gaacagagac cttgggatac tgcacggact tccaggcagt gccaggctgt
3301 ggaattgggt gcaaagtcag caacgtggaa ggcatcctgg cccacagtga gcgccctttg
3361 agtgcaccgg ccagtcacct gaatgaggct ggcagccttc ccgcagaaaa agatgcagcc
3421 ccccagacct tctctgtgct gattggaaac cgtgagtggc tgaggcgcaa cggtttaacc
3481 atttctagcg atgtcagtga cgctatgaca gaccacgaga tgaaaggaca gacagccatc
3541 ctggtggcta ttgacggtgt gctctgtggg atgatcgcaa tcgcagacgc tgtcaagcag
3601 gaggctgccc tggctgtgca cacgctgcag agcatgggtg tggacgtggt tctgatcacg
3661 ggggacaacc ggaagacagc cagagctatt gccacccagg ttggcatcaa caaagtcttt
3721 gcagaggtgc tgccttcgca caaggtggcc aaggtccagg agctccagaa taaagggaag
3781 aaagtcgcca tggtggggga tggggtcaat gactccccgg ccttggccca ggcagacatg
3841 ggtgtggcca ttggcaccgg cacggatgtg gccatcgagg cagccgacgt cgtccttatc
3901 agaaatgatt tgctggatgt ggtggctagc attcaccttt ccaagaggac tgtccgaagg
3961 atacgcatca acctggtcct ggcactgatt tataacctgg ttgggatacc cattgcagca
4021 ggtgtcttca tgcccatcgg cattgtgctg cagccctgga tgggctcagc ggccatggca
4081 gcctcctctg tgtctgtggt gctctcatcc ctgcagctca agtgctataa gaagcctgac
4141 ctggagaggt atgaggcaca ggcgcatggc cacatgaagc ccctgacggc atcccaggtc
4201 agtgtgcaca taggcatgga tgacaggtgg cgggactccc ccagggccac accatgggac
4261 caggtcagct atgtcagcca ggtgtcgctg tcctccctga cgtccgacaa gccatctcgg
4321 cacagcgctg cagcagacga tgatggggac aagtggtctc tgctcctgaa tggcagggat
4381 gaggagcagt acatctgatg acttcaggca ggcgggccgg ggcagggact tgcctccact
4441 caccacaag
//